Journals / Üroonkoloji Bülteni / 2020 / Cilt: 19 - Sayı: 2

The Effect of Tumor Localization and Clinicopathological Factors on Intravesical Recurrence and Survival in Primary Upper Urinary Tract Urothelial Tumors

Pages
85–91
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ten-year overall survival of patients with ureteral tumors was 50% (35.4% side effect) (Log rank test=0.012).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to investigate the factors affecting intravesical recurrence and survival in patients undergoing radical nephroureterectomy and bladder cuff excision due to primary upper urinary system urothelial tumor (UUST) in our clinic.
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Key Findings & Data:Materials and Methods: The data of 52 patients who were operated for primary UUST between 2008 and 2018 were retrospectively evaluated.
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Conclusion & Impact:Ten-year overall survival of patients with ureteral tumors was 50% (35.4% side effect) (Log rank test=0.012).
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: We aimed to investigate the factors affecting intravesical recurrence and survival in patients undergoing radical nephroureterectomy and bladder cuff excision due to primary upper urinary system urothelial tumor (UUST) in our clinic. Materials and Methods: The data of 52 patients who were operated for primary UUST between 2008 and 2018 were retrospectively evaluated. All patients underwent preoperative computed tomography and magnetic resonance urography. Tumor localizations were grouped according to the ureteropelvic compound. During the follow-up period after radical surgery, the patients underwent physical examination, routine blood tests and radiological evaluation. The patients were followed up quarterly in the first two years, every six months for the next two years and then yearly with cystoscopy. Results: Thirteen female and 39 male patients with an average age of 60.5±10.35 years were included in the study. Mean follow-up time was 66.8±38.2 months. Thirty (58%) patients had renal tumors, 13 (25%) patients had ureteral tumors and 9 (17%) patients had multifocal tumors. Intravesical recurrence was detected in 9 (69%) patients with ureteral tumor (p=0.047). Ten-year overall survival of patients with ureteral tumors was 50% (35.4% side effect) (Log rank test=0.012). Recurrent-free survival was significantly worse in ureteral tumors (Hazard ratio:3, p=0.04). Conclusion: The ureteral tumor group was significantly worse in terms of postoperative intravesical recurrence and overall survival and recurrence-free survival.

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Cite This Article

İZOL, V., KIZILGÖK, B., DEĞER, M., BAYAZIT, Y., TANSUĞ, M. Z. (2020). The Effect of Tumor Localization and Clinicopathological Factors on Intravesical Recurrence and Survival in Primary Upper Urinary Tract Urothelial Tumors. Üroonkoloji Bülteni, Cilt: 19 - Sayı: 2, 85–91. https://ajindex.com/articles/334425

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References (13)

  1. Siegel RL1, Miller KD, Jemal A., et al. Cancerstatistics, 2015. CA Cancer J Clin 2015;65:5-29
  2. Behfar Ehdaie, Shahrokh F. Shariat, Caroline, Savage, Jonathan Coleman, Guido Dalbagni. Postoperative Nomogram for Disease Recurrenceand Cancer-Specific Death for Upper Tract Urothelial Carcinoma: Comparisonto American Joint Committee on Cancer Staging Classification. Urology Journal 2014;11:2
  3. Seisen T, Granger B, Colin P, et al. A Systematic Reviewand Metaanalysis of Clinicopathologic Factors Linked to Intravesical Recurrence After Radical Nephroureterectomy to Treat Upper Tract Urothelial Carcinoma. EurUrol 2015;67:1122-1133
  4. Sagalowsky A, Jarrett T. Üst Üriner Yol ve ÜreterinÜrotelyal Tümörleri, Campbell-WalshUrology, Tenth Edition 2014;1530
  5. Bayazıt Y, İzol V, Laparoskopik radikal nefroüreterektomi sırasında hücre ekimi riskini azaltmada distalüreter ve mesane irrigasyon tekniği.10. Üroonkoloji Kongresi Bildiri Özetleri Kitabı, P-18, 131, Antalya, 26-30 Ekim 2011
  6. Margulis V, Shariat SF, Matin SF, et al. Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration. Cancer 2009;115:1224-1233
  7. Simsir A, Sarsik B, Cureklibatur İ, et al. Prognostic factors for upper urinary tracturo the lial carcinomas: stage, grade, andsmokingstatus. IntUrolNephrol 2011;43:1039
  8. Zou L, Zhang L, Zhang H, Jiang H, Ding Q. Comparison of postoperative intravesical recurrence and oncological outcomes after open versus laparoscopic nephroureterectomy for upper urinary tracturo the lial carcinoma. World J Urol 2014;32:565-570
  9. Tanaka N, Kikuchi E, Kanao K, et al. Thepredictivevalue of positive urinecytology for outcomes following radical nephroureterectomy in patients with primary upper tracturo the lial carcinoma: a multi institutional study. Urol Oncol 2014;32:19-26
  10. Shariat, SF, Godoy G, Lotan Y, et al. Advanced patientage is associated within ferior cancer-specific survival after radical nephroureterectomy. BJU Int 2010;105:1672
  11. World Health Organization (2015) World Report on Ageingand Health
  12. Yafi FA, Novara G, Shariat SF, et al. Impact of tumour location versus multifocality in patients with upper tract uro the lial carcinomatre ated with nephroureterectomy and bladder cuffexcision: a homogeneous series without perioperative chemotherapy. BJU Int 2012;110:7-13
  13. Ouzzane A, Colin P, Xylinas E, et al. Ureteral and multifocaltumours have worse prognosis than renal pelvictumours in urothelialcarc