SavedAdd your journal

Journals / Üroonkoloji Bülteni / 2016 / Cilt: 15 - Sayı: 3

Controversies in Radical Cystectomy: Meta-Analysis and Systemic Comparison of Open Surgery with Laparoscopic and Robotic Surgery

Radikal Sistektomide Karşıtlıklar: Laparoskopik ve Robotik Cerrahi ile Açık Cerrahinin Meta-Analiz ve Sistemik Analizler Eşliğinde Karşılaştırılması

MEHMET KAYNAR
SERDAR GÖKTAŞ
Pages
107–112
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Considering the results obtained in experienced centers as well as longterm oncologic outcomes of large patient series forming samples of the whole population, changes in the standard treatment modality of invasive bladder tumors seem to be unavoidable

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Open radical cystectomy (ORC) is the standard treatment modality in high-risk non-muscle-invasive and invasive bladder carcinoma.
📊
Key Findings & Data:Although it has some advantages, oncologic outcomes of ORC are associated with high morbidity and mortality risks.
💡
Conclusion & Impact:Considering the results obtained in experienced centers as well as longterm oncologic outcomes of large patient series forming samples of the whole population, changes in the standard treatment modality of invasive bladder tumors seem to be unavoidable
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Open radical cystectomy (ORC) is the standard treatment modality in high-risk non-muscle-invasive and invasive bladder carcinoma. Although it has some advantages, oncologic outcomes of ORC are associated with high morbidity and mortality risks. In line with recent developments in urotechnology, the minimally invasive treatment modalities, such as laparoscopic radical cystectomy (LRC) and robotic-assisted radical cystectomy (RARC) have emerged as an alternative to ORC. Compared to ORC, both treatment modalities have effective surgical and similar oncological outcomes as reported in various studies. However, due to inherent difficulties in the practice of LRC and high costs of RRC have hindered these two treatment modalities to become widespread. Considering the results obtained in experienced centers as well as longterm oncologic outcomes of large patient series forming samples of the whole population, changes in the standard treatment modality of invasive bladder tumors seem to be unavoidable

Özet

Kas invaziv ve yüksek riskli invaziv olmayan mesane kanserlerinin tedavisinde açık radikal sistektomi (ARS) standart tedavi yöntemidir. ARS avantajlı onkolojik sonuçlarına rağmen yüksek morbidite ve mortalite oranlarına sahiptir. Son yıllarda üroteknolojideki gelişmeler ile birlikte minimal invaziv tedavi seçeneklerinden laparoskopik radikal sistektomi (LRS) ve robot yardımlı radikal sistektomi (RYRS) mesane tümörlerinin tedavisinde ARS'ye alternatif olarak ortaya çıkmıştır. Her iki yöntemin etkin cerrahi ve benzer onkolojik sonuçlarının olduğu çeşitli çalışmalarda gösterilmiştir. Fakat LRS'deki uygulama zorluğu ve RYRS'deki yüksek maliyetler nedeni ile yaygınlaşması kısıtlanmaktadır. Deneyimli merkezlerin uygulamalarının yanında genel popülasyona dayalı geniş hasta serilerini içeren uzun süreli onkolojik sonuçların karşılaştırmalı olarak ortaya konması ile birlikte invaziv mesane tümörlerinin standart tedavisindeki manzaranın değişmesi kaçınılmaz görünmektedir.

🔖

Cite This Article

KAYNAR, M., GÖKTAŞ, S. (2016). Controversies in Radical Cystectomy: Meta-Analysis and Systemic Comparison of Open Surgery with Laparoscopic and Robotic Surgery. Üroonkoloji Bülteni, Cilt: 15 - Sayı: 3, 107–112. https://ajindex.com/articles/334406

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013;63:11-30.
  2. Witjes JA, Compérat E, Cowan NC, et al. Guidelines on muscle invasive and metastatic bladder cancer. EAU Guideline 2013:1-82.
  3. Stenzl A, Cowan NC, De Santis M. et al. Treatment of muscle-invasive and metastatic bladder cancer: update of the EAU guidelines. Eur Urol 2011;59:1009-1018.
  4. Cohen SA, Mirheydar HS, Parsons JK, et al. Minimally invasive cystectomy is associated with improved perioperative patient safety outcomes compared with open cystectomy in a national cohort. Urology 2014;84:314-319.
  5. Sanchez de Badajoz E, Gallego Perales JL, Reche Rosado A, et al. Radical cystectomy and laparoscopic ileal conduit. Arch Esp Urol 1993;46:621-624.
  6. Gill IS, Fergany A, Klein EA, et al. Laparoscopic radical cystoprostatectomy with ileal conduit performed completely intracorporeally: the initial 2 cases. Urology 2000;56:26-29.
  7. Gill IS, Kaouk JH, Meraney AM, et al. Laparoscopic radical cystectomy and continent orthotopic ileal neobladder performed completely intracorporeally: the initial experience. J Urol 2002;168:13-18.
  8. Guillotreau J, Gamé X, Mouzin M, et al. Radical cystectomy for bladder cancer: morbidity of laparoscopic versus open surgery. J Urol 2009;181:554-559.
  9. Fonseka T, Ahmed K, Froghi S, et al. Comparing robotic, laparoscopic and open cystectomy: a systematic review and meta-analysis. Arch Ital Urol Androl 2015;87:41-48.
  10. Aboumarzouk OM, Hughes O, Narahari K, et al. Safety and feasibility of laparoscopic radical cystectomy for the treatment of bladder cancer. J Endourol 2013;27:1083-1095.
  11. Tang K, Li H, Xia D, et al. Laparoscopic versus open radical cystectomy in bladder cancer: a systematic review and meta-analysis of comparative studies. PLoS One 2014;9:e95667. Khan MS, Gan C, Ahmed K, et al. A Single-centre Early Phase Randomised Controlled Three-arm Trial of Open, Robotic, and Laparoscopic Radical Cystectomy (CORAL). Eur Urol 2016;69:613-621.
  12. Haber GP, Campbell SC, Colombo JR Jr et al. Perioperative outcomes with laparoscopic radical cystectomy: "pure laparoscopic" and "open- assisted laparoscopic" approaches. Urology 2007;70:910-915.
  13. Gregori A, Galli S, Goumas I, et al. A cost comparison of laparoscopic versus open radical cystoprostatectomy and orthotopic ileal neobladder at a single institution. Arch Ital Urol Androl 2007;79:127-129.
  14. Ha US, Kim SI, Kim SJ, et al. Laparoscopic versus open radical cystectomy for the management of bladder cancer: mid-term oncological