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Journals / Üroonkoloji Bülteni / 2018 / Cilt: 17 - Sayı: 4

Genomic Evaluation of Testicular Germ Cell Tumors and its Role in Treatment Planning

Ilker KİLİCCİOGLU
ECE KONAÇ
Sinan SÖZEN
Pages
138–142
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we briefly discussed the current information on some risk factors and genomic factors involved in the development of TGCTs

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The incidence of testicular germ cell tumors (TGCT) has significantly increased over the last 40 years and continues to increase among the young male population.
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Key Findings & Data:Although TGCTs respond well to chemotherapy, 20-30% of patients display classical chemotherapy resistance.
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Conclusion & Impact:In this review, we briefly discussed the current information on some risk factors and genomic factors involved in the development of TGCTs
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

The incidence of testicular germ cell tumors (TGCT) has significantly increased over the last 40 years and continues to increase among the young male population. The geographical differences show that a combination of genetic and environmental factors play a role in the pathogenesis of TGCT. However, since the actual mechanisms involved in the development of this disease have still not been fully explained, studies at the genomic level have gained importance. Although TGCTs respond well to chemotherapy, 20-30% of patients display classical chemotherapy resistance. There exists a need for detailed investigation of the molecular mechanisms responsible for such resistance. In this review, we briefly discussed the current information on some risk factors and genomic factors involved in the development of TGCTs

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Cite This Article

KİLİCCİOGLU, I., KONAÇ, E., SÖZEN, S. (2018). Genomic Evaluation of Testicular Germ Cell Tumors and its Role in Treatment Planning. Üroonkoloji Bülteni, Cilt: 17 - Sayı: 4, 138–142. https://ajindex.com/articles/334354

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