Journals / Van Tıp Dergisi / 2017 / Cilt: 24 - Sayı: 2

Evaluation of Type 1 Diabetes Mellitus Patients

Tip 1 Diyabet Mellitus Olgularının Değerlendirilmesi

Pages
85–90
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: In our study, it was found that in our province type 1 DM is more common in boys than girls; ketoacidosis is more frequently seen at the time of diagnosis; the onset of diagnosis have 2 peaks under 5 years of age and at early puberty; most common comorbid disease is celiac disease; and most common chronic complication is nephropathy.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this retrospective study, we aimed to identify demographic characteristics, age at onset, metabolic control status, findings at diagnosis and comorbid conditions in patients (aged 0-18 years) with type 1 diabetes mellitus (DM).
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Key Findings & Data:Materials and Methods: The study included 101 patients aged 0-18 years with previous or recent diagnosis of type 1 DM based on WHO criteria who were followed in pediatric endocrinology department of Yüzüncü Yıl University Faculty of Medicine.
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Conclusion & Impact:Conclusions: In our study, it was found that in our province type 1 DM is more common in boys than girls; ketoacidosis is more frequently seen at the time of diagnosis; the onset of diagnosis have 2 peaks under 5 years of age and at early puberty; most common comorbid disease is celiac disease; and most common chronic complication is nephropathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this retrospective study, we aimed to identify demographic characteristics, age at onset, metabolic control status, findings at diagnosis and comorbid conditions in patients (aged 0-18 years) with type 1 diabetes mellitus (DM). Materials and Methods: The study included 101 patients aged 0-18 years with previous or recent diagnosis of type 1 DM based on WHO criteria who were followed in pediatric endocrinology department of Yüzüncü Yıl University Faculty of Medicine. Results: Of the patients with type 1 DM, there were 43 girls (42.6%) and 58 boys (57.4%). Mean age at diagnosis was 8.3 ± 8.0 years (min-max: 1-16 years). At the time of presentation, there was diabetic ketoacidosis in 51.6%, hyperglycemia in 27.7% and ketonemia in 20.7% of the patients. Celiac disease was detected in 6 patients with type 1 DM (%5.9) while no comorbid autoimmune disease was detected in 95 patients (94.1%). Diabetic nephropathy developed in 2 children with type 1 DM (1.9%) while no chronic complication of diabetes mellitus was observed in 99 children (98.1%). Metabolic control was considered to be good in 8 (7.9%), moderate in 29 (28.7%) and poor in 64 of children (63.4%). Conclusions: In our study, it was found that in our province type 1 DM is more common in boys than girls; ketoacidosis is more frequently seen at the time of diagnosis; the onset of diagnosis have 2 peaks under 5 years of age and at early puberty; most common comorbid disease is celiac disease; and most common chronic complication is nephropathy.

Özet

Amaç: Retrospektif olarak planlanan çalışmada; 0-18 yaş arası tip 1 diyabetes mellituslu (DM) hastalarda demografik özellikler, tanı yaşları, metabolik kontrol durumları, tanı anındaki bulguları ve diyabete eşlik eden hastalıklarının olup olmadığının belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmamıza, Yüzüncü Yıl Üniversitesi Tıp Fakültesi çocuk endokrinoloji polikliniğimizden takip ve tedavileri yapılan; "WHO" kriterlerine göre tanı konulmuş eski ve yeni tanılı 0-18 yaş aralığında, 101 tip 1 DM hastası çocuk alındı. Bulgular: Tip 1 DM' li hastaların 43'ü (%42.6) kız, 58'i (%57.4) erkekti. Tanı yaşı ortalaması 8.3 ± 8.0 yıl (min:1 yıl, max: 16 yıl) idi. Hastaların başvuru anında %51.6' sında diyabetik ketoasidoz, %27.7' sinde hiperglisemi ve %20.7' sinde ketonemi saptandı. Eşlik eden otoimmün hastalıklar açısından değerlendirildiğinde tip 1 DM'lu 6 kişide (5.9%) çölyak hastalığı tespit edilmişken, 95 kişide (94.1%) eşlik eden herhangi bir otoimmün hastalık saptanmamıştı. Tip 1 DM'lu çocukların 2'sinde (1.9%) diyabetik nefropati gelişmişken, 99'unda (98.1%) diyabetin herhangi bir kronik komplikasyonu saptanmamıştı. Hastaların 8'i (7.9%) iyi metabolik kontrollü, 29'u (28.7%) orta metabolik kontrollü, 64'ü (63.4%) kötü metabolik kontrollü olarak saptandı. Sonuçlar: Çalışmamızda tip 1 DM' nin ilimizde erkek çocuklarda kızlara göre daha sık olduğu, tanıda ketoasidozla başvurunun daha çok görüldüğü, diyabetin ortaya çıktığı doruk yaşların 5 yaş öncesi ve erken puberte yaşları olduğu, en sık eşlik eden otoimmun hastalığın çölyak hastalğı ve en sık kronik komplikasyon olarak da nefropati geliştiği saptanmıştır.

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Cite This Article

BALA, K. A., DİDİN, M., KABA, S., ASLAN, O., KARAMAN, S., KOCAMAN, S. K., DOĞAN, M. (2017). Evaluation of Type 1 Diabetes Mellitus Patients. Van Tıp Dergisi, Cilt: 24 - Sayı: 2, 85–90. https://ajindex.com/articles/334035

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