Journals / Van Tıp Dergisi / 2019 / Cilt: 26 - Sayı: 3

Rhombencephalitis due to Listeria Monocytogenes Infection in the Immunocompetent Patient: A Case Report

İmmün Yetmezliği Olmayan Hastada Listeria Monocytogenes Enfeksiyonuna Bağlı Rhombensefalit: Olgu Sunumu

Pages
377–380
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early recognition and treatment is the most important prognostic factor.

📌 3 Key Takeaways

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Objective & Hypothesis:Listeria monocytogenes is a gram positive microorganism that can cause multiorgan involvement.
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Key Findings & Data:Progressive brainstem symptoms and seizures can be added. 27 year old male patient was presented with dizziness and ataxia lasting for 15 days.
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Conclusion & Impact:Early recognition and treatment is the most important prognostic factor.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Listeria monocytogenes is a gram positive microorganism that can cause multiorgan involvement. If brainstem involvement due to this microorganism occurs, it is called rhombencephalitis. There are nonspecific prodromal symptoms at the begining. Progressive brainstem symptoms and seizures can be added. 27 year old male patient was presented with dizziness and ataxia lasting for 15 days. It was learned that he had traveled to Saudi Arabia 2 months ago. Restricted abduction of left eye, left facial hemihypoesthesia, ataxia, dysmetria and bilateral Babinski sign positive were detected. In brain imaging, hyperintensity was detected at T2, DWI and FLAIR sequences in mesencephalon, pons and bulbus localization. Listeria monocytogenes in blood culture was detected. Immune deficit was not detected. Intravenous 150 mg/kg/day ampicillin was started. On the 12th day of admission, the patient died associated with respiratory deficit. Listeria monocytogenes should be considered in patients with resistant of classical antibiotic treatment cases who present with atypical brainstem symptoms. Typical brainstem involvement on brain imaging can be useful for diagnosis. Early recognition and treatment is the most important prognostic factor.

Özet

Listeria monositogenes; birçok organ tutulumu yapabilen gram pozitif bir bakteridir. Bu mikroorganizmaya bağlı beyin sapı tutulumu meydana gelirse buna rombensefalit adı verilmektedir. Başlangıçta nonspesifik prodromal semptomlar görülür. Sonrasında progresif beyin sapı semptomları ve nöbetler izlenebilir. Yirmi yedi yaşında erkek hasta, 15 gündür olan baş dönmesi ve denge bozukluğu yakınması ile başvurdu. Özgeçmişinden, 2 ay önce Suudi Arabistan’a seyahat etmiş olduğu öğrenildi. Sol gözde abdüksiyon kısıtlılığı, sol yüz yarısında hipoestezi, ataksi, dismetri ve bilateral Babinski bulgusu pozitifliği saptandı. Beyin görüntülemede mezensefalon, pons ve bulbus lokalizasyonunda T2, DWI ve FLAIR sekanslarda hiperintensite saptandı. Kan kültüründe Listeria monositogenes üredi. İmmün defisit saptanmadı. İntravenöz 150 mg/kg/gün dozunda ampisilin başlandı. Yatışının 12. günü solunum yetmezliği nedeni ile kaybedildi. Atipik beyin sapı belirtileri ile başvuran ve klasik antibiyotik tedaviye dirençli olgularda Listeria monositogenes düşünülmelidir. Beyin görüntülemedeki tipik beyin sapı tutulumu tanı için yararlı olabilmektedir. Hızlı tanınması ve tedavinin sağlanması en önemli prognostik unsurdur.

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Cite This Article

EREN, F., ÖZTÜRK, Ş. (2019). Rhombencephalitis due to Listeria Monocytogenes Infection in the Immunocompetent Patient: A Case Report. Van Tıp Dergisi, Cilt: 26 - Sayı: 3, 377–380. https://ajindex.com/articles/333898

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