Journals / Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences / 2005 / Cilt: 21 - Sayı: 3

The importance of arterial blood gases in the diagnosis of experimentally induced respiratory tract diseases in lambs

Kuzularda deneysel oluşturulan akut solunum sistemi enfeksiyonlarının teşhisinde arteriyal kan gazlarının önemi

Pages
119–125
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results of this study showed that, arterial blood gases did not influenced in acute respiratory enfection, but venouse blood gases did more influenced in acute res­piratory disease, therefore, evaulation of venouse blood gases in the diagnosis of respiratory disease was found to more benifical.

📌 3 Key Takeaways

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Objective & Hypothesis:The importance of arterial and venouse blood gas in the diagnosis of experimentally induced respiratory tract diseases in lambs and to the most reliable Which parameters in the diagnosis of disaese were aimed to determine in this study.
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Key Findings & Data:Hie lambs divided to control (6 lambs) and experimental (7 lambs) groups.
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Conclusion & Impact:The results of this study showed that, arterial blood gases did not influenced in acute respiratory enfection, but venouse blood gases did more influenced in acute res­piratory disease, therefore, evaulation of venouse blood gases in the diagnosis of respiratory disease was found to more benifical.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:vücut sıcaklığı · kalp hızı · parainfluenza 3 virüsü

Abstract

The importance of arterial and venouse blood gas in the diagnosis of experimentally induced respiratory tract diseases in lambs and to the most reliable Which parameters in the diagnosis of disaese were aimed to determine in this study. Hie lambs divided to control (6 lambs) and experimental (7 lambs) groups. Pasteurella haemolytica (8x $10^8$ CFU/ ml), Clebsiella pneurnoniae (8x $10^8$ CFU/ml) and Paraenfluenza 3 virüse were inoculated by intratracheal for induced res­piratory tract diseases in the lambs (experimental groups). Blood samples were taken from tie femoral arteria and the ju­gular vein once in the control group of lambs. Blood samples were taken from the femoral arteria and the jugular vein on days 1th , 2th, 3th, and 4th of the infection in the experimental group of lambs. The WBC (p<0.001), body temperature (p<0.OO1), respiratory rate (p<0.001), and heart rate (p<0.01) were significantly increased in tie experimental group of lambs compared with the control group of lambs. pH (p<0.O1), pCO2 (p<0.O1), pO2 (p<0.05), and oxygen saturation (p<0.05) in venouse blood were significantly different in tie the experimental group of lambs compared with tie control group of lambs. pCO2 (p<0.01) in arterial blood was significantly different in the tie experimental group of lambs compared with the control group of lambs. In the histopaihoiogic examination, interstitial pneumonia and pneumonia with ab-cessation was determined in the lung of experimental group of the lambs. The results of this study showed that, arterial blood gases did not influenced in acute respiratory enfection, but venouse blood gases did more influenced in acute res­piratory disease, therefore, evaulation of venouse blood gases in the diagnosis of respiratory disease was found to more benifical.

Özet

Bu araştırmada, kuzularda deneysel oluşturulan solunum sistemi enfeksiyonlarının teşhisinde arteriyal ve venöz kan gazlarının önemini belirlemek ve hangi parametrelerin hastalığın teşhisinde daha güvenilir olduğunu ortaya koymak amaçlanmıştır. Kuzular deneme (7 kuzu) ve kontrol (6 kuzu) grubu olmak üzere 2 gruba ayrıldı. Kuzulara Pastorella hemolitica (8x $10^8$ bakteri/ml), Klebsiella pnömoni (8x $10^8$ bakteri/ml) ve Paraînfuenza 3 virus suşları traka içi verilerek en­feksiyon oluşturuldu. Kontrol grubundaki kuzulardan bir kez arteriyai ve vemz kan örnekleri alınırken, deneme grubundaki kuzulardan enfeksiyonun 1., 2., 3. ve 4. günlerinde arteriyai ve venöz kan örnekleri alındı. Deneme grubu kuzuların WBC sayısı (p<0.001), beden ısısı (p<0.001), kalp (p<0.O1) ve solunum sayılan (p<0.001) kontrol grubuna göre önemli oranda yüksekti. Arteriyai kan gazlarında sadece pCO2'de farklılık (p<0.01) gözlenirken, venöz kan gazlannda pH (p<0.O1), pCO2 (p<0.01), pO2(p<0.05) ve O2SAT (p<0.05) düzeylerinde kayda değer farklılık tespit edildi. Histopatolojik muayenede de­neme grubu kuzulann akciğerlerinde intertisiyal ve apseli pnömoni gözlendi. Sonuç olarak, kuzuların akut akciğer en­feksiyonlarında arteriyal kan gazların çok fazla etkilenmediği ve çoğunlukla venöz kan gazlannın etkilendiği, bu yüzden has­talığın teşhisinde venöz kan gazlannın değerlendirilmesi İle daha sağlıklı sonuç alınabileceği kanısına varıldı.

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Cite This Article

OK, M., GÜZELBEKTEŞ, H., ŞEN, İ., COŞKUN, A. (2005). The importance of arterial blood gases in the diagnosis of experimentally induced respiratory tract diseases in lambs. Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences, Cilt: 21 - Sayı: 3, 119–125. https://ajindex.com/articles/333679

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References (13)

  1. Adams, R., Holland, M.D., Aldridge, B., Garry, F.B., and Ödde, K.G. (1991). Arterial blood sample collection from newborn calf. Vet. Res. Com., 15,5, 387-394.
  2. Apley, M.D. (2003). Susceptibility testing for bovine res­piratory and enteric diseases. Vet. din. Food Anim. 19, 625-645.
  3. Aslan, V., Ok, M., Maden, M. Sevinç, M. ve Kurtoğlu, F. (1993). Pneumo-enteritli buzağılarda kan proteinleri ve glutaraldehit testinin teşhis ve prognozdaki önemi. S.Ü. Vet. Fak. Derg. 9,1,36-40.
  4. Aslan, V., Maden, M., Erganiş, O., Birdane, F.M. ve Çorlu, M (2002). Clinical efficacy of florfenicol in the treatment of calf respiratory tract infections. Vet. Quart., 24,1,35-39.
  5. Aytuğ, N.C. (1987). Koyunların enzootik pneumonisi. S.Ü. Vet. Fak. Derg., 113-119.
  6. Ball, H.J., Connolly, M and Cassidy J. (1993). Pasteurella haemolitica serotypes isolated in Northern Ireland During 1989-1991. Br. Vet.,149, 561-570.
  7. Birdane, FM. (2001). Buzağılarda solunum yolu en­feksiyonlarının tanısında bronkoalveolar lavaj sıvısı mu­ayenelerinin önemi. Doktora tezi, S.Ü. Sağ. Bil. Enstitüsü. Konya. Gassier, E.F., Rudolph, K.M., Fowler, P., Coggins, V.L, Hunter, D.I. and Miller, M.W. (2001). Evaluation of ewe as a tool for increasing bighorn lamb survival following pas-teurellosis epizootics. Wildl Dis., 37,1, 49-57.
  8. Coghe.J., Uystepruyst, C.H., Bureau, F., detalleux, J., Art, T and Lekeux, P. (2000). Validation and prognostic value of plasma lactate measurement in bovine respiratory di­seases. Vet. J., 160, 2,139-146. Collie, d.D.S (1991). Blood gases and asid-base values in calves sampled from the brachial and coccygeal arteries. Br. Vet. J., 147,232-37.
  9. Constable, P.D., Streeter, R.N., Koenig, G.J., Perkins, N.R., Gothar, H.M. and Morin, D.E. (1997). Determinants and utility of the anion gap in predicting hyperlactatemia in cattle. J. Vet. Intern. Med., 11,2, 71-79.
  10. Çimtay, L, Şahin, T, Arserimkaya, N.B. (2000). Enzootik pnömonili besi sığırların tedavisinde amoksisilin'in et­kinliğinin araştırılması. Y.Y.Ü. Vet. Fak. Derg., 11, 2, 113116. Davies, R.L, Watson, P.J. and Caffrey, B. (2003). Com­parative analyses of pasteuralla multocida starins as­sociated with respiratory and vaginal trackts. Vet. Rec, 152, 1,7-10.
  11. Entin, P.L Robertshaw, D. And Rawson, R.E. (1998). Thermal drive contributes to hiperventilation during exer­cise in sheep. J. App. Physiology. 7,318-325.
  12. Gilmour, N.J.L (1978). Pasteurellosis in sheep. Vet. Rec,102, 100-102.
  13. Gilmour, N.J.L.(1990) Pasteurella heamolitica infections in young s