AI Summary & Key Takeaways
AI InsightImmunohistochemically, some tumour markers, such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), of the intermediate filament proteins, cytokeratin, and superficial antigens of hepatitis B virus was investigated, and alpha-fetoprotein (AFP) was founded to be positive.
📌 3 Key Takeaways
Abstract
Hepatocellular carcinoma, detected in a 4-years-old sheep, was described in the present study. Grossly, grayish-white coloured, 1.7x1.5x1cm in dimensions and well circumscribed, a solitary tumor mass were seen in the diaphragmatic aspect of the right lobe of liver. Microscopically, the neoplastic cells were arranged in solid pattern. Tumour was diagnosed as solid, poorly differentiated hepatocellular carcinoma. Immunohistochemically, some tumour markers, such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), of the intermediate filament proteins, cytokeratin, and superficial antigens of hepatitis B virus was investigated, and alpha-fetoprotein (AFP) was founded to be positive.
Özet
Bu raporda, 4 yaşındaki bir koyunda belirlenen HSK' olgusu tanımlandı. Makroskobik olarak, karaciğerin sağ lobunda grimtırak beyaz renkte, 1,7x1,5x1cm boyutlarında ve sınırlı soliter tümoral bir kitle görüldü. Mikroskobik olarak, tümör hücreleri genellikle solid yapılar, kimi bölgelerde de hepatik kordonlar oluşturmuştu. Tümör, az diferensiye solid HSK' olarak teşhis edildi. İmmunohistokimyasal olarak, tümör markerlerinden alpha-fetoprotein (AFP), karsinoembriyonik antijen (CEA), sitokeratin ve hepatit B virusu yüzey antigeni (HbsAg) araştırıldı. Bunlardan AFP tümör hücrelerinde, CEA ve sitokeratin ise sadece safra kapillarında pozitif bulundu.