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Journals / Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences / 1997 / Cilt: 13 - Sayı: 1

Determination of cyanide and thiocyanate levels in tissues in mice given SNP

Sodyum nitroprussit verilen farelerde dokulardaki siyanür ve tiyosiyanat düzeylerinin belirlenmesi

İbrahim PİRİNÇCİ
Sadettin TANYILDIZI
AHMET ATEŞŞAHİN
Haki KARA
Songül ÖZAYDIN
Pages
53–60
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The cyanide and thiocyanate levels in tissue samples increased after 12 h. and arrived the maximum levels at the different times according to doses.Then the cyanide and thiocyanate levels in samples decreased the same levels with control groups at 192 h.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, cyanide and thiocyanate levels at liver, spleen, kidney and muscle tissue samples obtained from mice which were given different doses sodium nitroprusside (SNP) were investigated.
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Key Findings & Data:Absorbances were measured at 532 nm.
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Conclusion & Impact:The cyanide and thiocyanate levels in tissue samples increased after 12 h. and arrived the maximum levels at the different times according to doses.Then the cyanide and thiocyanate levels in samples decreased the same levels with control groups at 192 h.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:fareler · kimyasal analizler · dalak

Abstract

In this study, cyanide and thiocyanate levels at liver, spleen, kidney and muscle tissue samples obtained from mice which were given different doses sodium nitroprusside (SNP) were investigated. The cyanide and thiocyanate levels in the samples were colorimetrically determined the oxidation of cyanide and thiocyanate by bromine water and coupling of pyridine - benzidine reagents. Absorbances were measured at 532 nm. The cyanide and thiocyanate levels in tissue samples increased after 12 h. and arrived the maximum levels at the different times according to doses.Then the cyanide and thiocyanate levels in samples decreased the same levels with control groups at 192 h.

Özet

Bu çalışmada farklı dozlarda sodyum nitroprussit (SNP) verilen farelerden elde edilen karaciğer, dalak, böbrek ve kas doku numunelerindeki siyanür ve tiyosiyanat düzeyleri araştırıldı. Numunelerdeki siyanür ve tiyosiyanat düzeyleri bu bileşiklerin bromlu su tarafından okside edilmesi ve piridin - benzidin bileşikleri ile bağlanması sonucu kolorimetrik olarak tayin edildi. Absorbansları 532 nm'de ölçüldü. Doku numunelerindeki siyanür ve tiyosiyanat düzeyleri 12. saatten itibaren yükselmeye başladı ve dozlara göre değişen zamanlarda maksimum düzeylere ulaştı. Daha sonra numunelerdeki siyanür ve tiyosiyanat düzeyleri 192. saatte kontrol guruplarına yakın düzeylere indi.

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Cite This Article

PİRİNÇCİ, İ., TANYILDIZI, S., ATEŞŞAHİN, A., KARA, H., ÖZAYDIN, S. (1997). Determination of cyanide and thiocyanate levels in tissues in mice given SNP. Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences, Cilt: 13 - Sayı: 1, 53–60. https://ajindex.com/articles/333567

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