Journals / Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences / 2006 / Cilt: 22 - Sayı: 1

Renal ultrasonographic findings in dogs with experimentally induced ethylene glycol nephrosis

Köpeklerde deneysel oluşturulan etilen glikol nefrozisinde renal ultrasonografik bulgular

Pages
21–26
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Ultrasonographic findings were not considered pat-hognomonic of ethylene glyco! nephrosis however, increase of cortical echogenicity within 12. hours can be assessed as pri­mary alteration for oxalate nephrosis.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study renal ultrasonographic changes were evaluated in six dogs administered commercial antifreeze (95% ethylene glycol) 2 ml/day/kg of BW, PO, during 3 days.
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Key Findings & Data:Prior an hour and after antifreeze was applied in 12.,36.,60. and 84. hours totally five times studies were made.
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Conclusion & Impact:Ultrasonographic findings were not considered pat-hognomonic of ethylene glyco! nephrosis however, increase of cortical echogenicity within 12. hours can be assessed as pri­mary alteration for oxalate nephrosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:tanı teknikleri · köpek · nefroz

Abstract

In this study renal ultrasonographic changes were evaluated in six dogs administered commercial antifreeze (95% ethylene glycol) 2 ml/day/kg of BW, PO, during 3 days. Prior an hour and after antifreeze was applied in 12.,36.,60. and 84. hours totally five times studies were made. Blood and urine samples were collected from dogs besides ultrasonographic exa­minations. It was evaluated ultrosonographically that within twelfth hours after ethylene glycol administration in 2 dogs and wit­hin thirtysixth hours in 4 dogs renal cortical echogenicity increased from mild to middle degrees. On the other hand within six­tieth hours in one dog and within eightyfourth hours in a total of four dogs central medullar regions and corticomedullary junction were sonolucent (Halo sign). While gastrointestinal system irritation and severe calcium oxalate crystaluria for two dogs were observed within 12. hours, oliguria and severe crystaluria for all dogs were determined after 36. hours. Most cli-nicolaboratory values were support to ultrasonographic diagnosis. Ultrasonographic findings were not considered pat-hognomonic of ethylene glyco! nephrosis however, increase of cortical echogenicity within 12. hours can be assessed as pri­mary alteration for oxalate nephrosis.

Özet

Sunulan çalışmada 2 ml/gün/kg CA dozunda ve üç gün süreyle peros ticari antifriz (%95 etilen glikol içeren) verilen altı köpekte renal ultrasonografik bulgular değerlendirildi. Çalışma süresince; antifriz verilmeden bir saat önce ve verildikten sonra 12., 36., 60. ve 84. saatlerde, toplam beş örnekleme yapıldı. Sonografik muayeneye paralel olarak kan ve idrar örnekleri alındı. Ultrason muayenesinde iki köpekte 12., dört köpekte ise 36. saatte başlamak üzere hafif ve orta derecelerde renal kortikal ekojenite artışı tespit edildi. 60. saatte bir, 84. saatte ise yapılan ultrasonografik kontrolde dört köpekte sentral medullar bölge ve kortikomedullar bağlantı bölgesinin belirgin sonolucent yapıda (hiperekoik) olduğu (Halo işareti) gözlemlendi. Klinik-laboratuvar bulgu olarak ilk 12 saatlik dönemdo gastrointestinal sistem irritasyonu ve iki kepekte yoğun kalsiyum okzalat kris-talüri belirlenirken, 36. saat sonrası oligüri ve tüm köpeklerde yoğun kristalüri tespit edildi. Klinik-laboratuvar analiz sonuçları ult­rasonografik çıktı üzerinde konulan tanıyı destekler nitelikteydi. Ultrasonografik bulgular etilen glikol nefrozisi için patognomik olmamakla birlikte, 12. saatte gözlenen kortikal ekojenite artışı okzalat nefrozisi için kabul edilebilir ilk değişiklik olarak kay­dedildi.

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Cite This Article

CİVELEK, T., BİRDANE, F. M., ELİTOK, B. (2006). Renal ultrasonographic findings in dogs with experimentally induced ethylene glycol nephrosis. Veteriner Bilimleri Dergisi . Eurasian Journal of Veterinary Sciences, Cilt: 22 - Sayı: 1, 21–26. https://ajindex.com/articles/333303

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