Journals / Türk Yoğun Bakım Dergisi / 2019 / Cilt: 17 - Sayı: 4

Retrospective Evaluation of Intensive Care Patients with H1N1 Virus

Yoğun Bakımda Takip Edilen H1N1 Olgularının Retrospektif Değerlendirilmesi

Pages
197–203
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The severity of pulmonary symptoms was the most important determinant of prognosis in patients with H1N1 and mortality increased in the presence of an underlying risk factor.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It is known that infections caused by influenza viruses are important public health problems all over the world.
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Key Findings & Data:In this study, the general features of influenza A (H1N1) virus infections were reviewed and the data of severe cases treated in intensive care unit were summarized.
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Conclusion & Impact:Conclusion: The severity of pulmonary symptoms was the most important determinant of prognosis in patients with H1N1 and mortality increased in the presence of an underlying risk factor.
🔬Design:Review & Systematic Survey
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: It is known that infections caused by influenza viruses are important public health problems all over the world. In this study, the general features of influenza A (H1N1) virus infections were reviewed and the data of severe cases treated in intensive care unit were summarized. Materials and Methods: Demographic characteristics, clinical, laboratory and radiological findings of 12 patients with H1N1 who were followed up in the intensive care unit between 2009 and 2013 were evaluated retrospectively. Results: The mean age was 33.9 years and 66% of the cases (n=8) were female. In 75% of the cases (n=9), an underlying cause such as respiratory, metabolic disease or pregnancy was detected. Eleven patients (92%) had acute respiratory distress syndrome, and ten patients (83%) had multi-organ failure and septic shock. Encephalitis was detected in two patients and peripheral circulatory defect was observed in two patients. The most common finding in the radiological examinations was infiltration of the lower and central zones of the lung. The length of intensive care stay was 1 to 18 days, and the mortality rate was 83% (n=10). Conclusion: The severity of pulmonary symptoms was the most important determinant of prognosis in patients with H1N1 and mortality increased in the presence of an underlying risk factor.

Özet

Amaç: İnfluenza virüslerinin neden olduğu enfeksiyonların tüm dünyada önemli bir halk sağlığı sorunu olduğu bilinmektedir. Bu çalışmada influenza A (H1N1) virüsünün neden olduğu enfeksiyonun genel özellikleri gözden geçirilmiş, yoğun bakımda tedavi edilen ağır olgulara ait veriler özetlenmiştir. Gereç ve Yöntem: Anesteziyoloji ve Reanimasyon Yoğun Bakım Ünitesi’nde 2009-2013 yılları arasında H1N1 tanısı ile takip edilen 12 olgunun demografik özellikleri, klinik, laboratuvar ve radyolojik bulguları retrospektif olarak değerlendirilmiştir. Bulgular: Olguların %66’sı (n=8) kadın ve yaş ortalaması 33,9 idi. Olguların %75’inde (n=9) solunumsal, metabolik hastalık veya gebelik gibi altta yatan bir neden tespit edildi. Olguların %92’sinde (n=11) akut solunum sıkıntısı sendromu, %83’ünde (n=10) çoklu organ yetmezliği ve septik şok tablosu mevcuttu. Takip sırasında iki olguda ensefalit, iki olguda periferik dolaşım bozukluğu tespit edildi. Olguların radyolojik incelemesinde en yaygın bulgunun akciğer alt ve santral zonların tutulması olduğu gözlendi. Yoğun bakım kalış süresi 1-18 gün arasında ve mortalite oranı %83 (n=10) idi. Sonuç: H1N1 olgularında prognozu belirleyen en önemli etkenin akciğer semptomlarının şiddeti olduğu ve altta yatan bir risk faktörü olması durumunda mortalitenin arttığı gözlenmiştir.

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Cite This Article

TÜRKTAN, M., KILIÇKAYA, R., GÜNDÜZ, H. M., ÖZCENGİZ, D. (2019). Retrospective Evaluation of Intensive Care Patients with H1N1 Virus. Türk Yoğun Bakım Dergisi, Cilt: 17 - Sayı: 4, 197–203. https://ajindex.com/articles/327735

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References (13)

  1. Simonsen L. The global impact of influenza on morbidity and mortality. Vaccine 1999;17(Suppl 1):S3-10
  2. Hsieh YH, Kelen GD, Dugas AF, Chen KF, Rothman RE. Emergency Physicians’ Adherence to Center for Disease Control and Prevention Guidance During the 2009 Influenza A H1N1 Pandemic. West J Emerg Med 2013;14:191-9
  3. Myers KP, Olsen CW, Gray GC. Cases of swine influenza in humans: a review of the literature. Clin Infect Dis 2007;44:1084-8
  4. Hegde NR, Kumar D, Rao PP, Kumari PK, Kaushik Y, Ravikrishnan R, et al. Development and preclinical testing of HNVAC, a cell culture-based H1N1 pandemic influenza vaccine from India. Vaccine 2014;32:3636-43
  5. Kilbourne ED. Influenza pandemics of the 20th century. Emerg Infect Dis 2006;12:9-14
  6. World Health Organisation. Clinical management of human infection with pandemic (H1N1) 2009: revised guidance. Last Accessed Date: 10.01.2010. Available from: http://www. who.int/csr/resources/publications/ swineflu/clinical_management/en/index. html 7. Libster R, Bugna J, Coviello S, Hijano DR, Dunaiewsky M, Reynoso N, et al. Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. N Engl J Med 2010;362:45- 55
  7. Chowell G, Bertozzi SM, Colchero MA, Lopez-Gatell H, Alpuche-Aranda C, Hernandez M, et al. Severe respiratory disease concurrent with the circulation of H1N1 iInfluenza. N Engl J Med 2009;361:674-9
  8. Grijalva-Otero I, Talavera JO, SolorzanoSantos F, Vazquez-Rosales G, Vladislavovna-Doubova S, Pérez-Cuevas R, et al. Critical analysis of deaths due to atypical pneumonia during the onset of the influenza A (H1N1) virus epidemic. Arch Med Res 2009;40:662-8
  9. Kojicic M, Kovacevic P, Bajramovic N, Batranovic U, Vidovic J, Aganovic K, et al. Characteristics and outcome of mechanically ventilated patients with 2009 H1N1 influenza in Bosnia and Herzegovina and Serbia: impact of newly established multidisciplinary intensive care units. Croat Med J 2012;53:620-6
  10. Kumar TC, Shivakumar NS, Deepak TS, Krishnappa R, Goutam MS, Ganigar V. H1N1-infected Patients in ICU and Their Clinical Outcome. N Am J Med Sci 2012;4:394-8
  11. Paredes G, Cevallos C. Acute respiratory distress syndrome during the 2009 H1N1 influenza A pandemic in Ecuador. Med Intensiva 2010;34:310-7
  12. Rohani P, Jude CM, Chan K, Barot N, Kamangar N. Chest Radiological Findings of Patients With Severe H1N1 Pneumonia Requiring Intensive Care. J Intensive Care Med 2016;31:51-60
  13. Louie JK, Acosta M, Jamieson DJ, H