Journals / Türk Yoğun Bakım Dergisi / 2020 / Cilt: 18 - Sayı: 1

Macrophage Activation Syndrome in COVID-19 Intensive Care: A Case Report

Yoğun Bakımda COVID-19 Seyrinde Makrofaj Aktivasyon Sendromu Gelişen Olgu: Olgu Sunumu

Pages
57–60
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

He showed no sequela and has completely recovered.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:T Macrophage activation syndrome is a life-threatening condition resulting from the destruction of organs and tissues secondary to excessive activation of the immune system.
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Key Findings & Data:We have reported here the case of a 44-yearold patient who was treated with tocilizumab for hemophagocytic syndrome that developed during his corona virus infection.
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Conclusion & Impact:He showed no sequela and has completely recovered.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

T Macrophage activation syndrome is a life-threatening condition resulting from the destruction of organs and tissues secondary to excessive activation of the immune system. The cytokine storm that develops during a corona virus infection has some overlapping laboratory and clinical findings to the hemophagocytic syndrome. It is curcial to support the diagnosis and differential diagnosis of this disease with successive measurements of the inflammation markers so as to initiate the treatment process immediately. We have reported here the case of a 44-yearold patient who was treated with tocilizumab for hemophagocytic syndrome that developed during his corona virus infection. The patient was sucessfully treated and monitored as per the pandemic requirement and then discharged. He showed no sequela and has completely recovered.

Özet

Z Makrofaj aktivasyonu sendrom, immün sitemin aşırı şekilde aktivasyonuna sekonder organ ve dokularda oluşan yıkım nedeniyle hayatı tehdit eden bir durumdur. Koronavirüs enfeksiyonu sırasında gelişen sitokin fırtınasında da hemofagositik sendroma benzer aynı zamanda farklı labaratuvar ve klinik bulgular görülür. Bu nedenle hastalığın tanı ve ayırıcı tanısının enflamasyon belirteçlerinin ardışık ölçümleri ile desteklenmesi ve acilen tedaviye başlanması gerekmektedir. Kırk dört yaşında olan olguya, koronavirüs enfeksiyonu sırasında gelişen hemofagositik sendrom nedeniyle tocilizumab tedavisi uygulandı. Hasta, yapılan takiplerinde tamamen düzelmesi üzerine tekrar pandemi servisine alınıp, sonrasında sekelsiz bir şekilde taburcu edildi.

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Cite This Article

ÇAKIR, T., GÜRSOY, C., TOPÇUOĞLU, N. (2020). Macrophage Activation Syndrome in COVID-19 Intensive Care: A Case Report. Türk Yoğun Bakım Dergisi, Cilt: 18 - Sayı: 1, 57–60. https://ajindex.com/articles/327675

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