Journals / Van Veterinary Journal / 2015 / Cilt: 26 - Sayı: 2

Investigation of Hematological and Biochemical Parameters, Clinical Findings and Rumen Content in The Different Phases of Experimental Ruminal Acidosis in Sheep

Koyunların Deneysel Ruminal Asidozisinin Farklı Safhalarında Klinik Bulgular, Rumen İçeriği, Hematolojik ve Biyokimyasal Parametrelerin Araştırılması

Pages
77–85
Publication Date
2015-08-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, evaluation of clinical and laboratory findings in ruminal acidotic animals those finding must be consideration for determination of prognosis and treatment planning was concluded

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to investigate clinical and laboratory findings of 12 g/kg and 18 g/kg of glucoseinduced different phases of experimental ruminal acidosis.
📊
Key Findings & Data:The materials of the study were consisted 12 healthy rams ages between 2-3 and 51-62 kg of weight.
💡
Conclusion & Impact:As a result, evaluation of clinical and laboratory findings in ruminal acidotic animals those finding must be consideration for determination of prognosis and treatment planning was concluded
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Koyun · Deneysel · Ruminal asidozis

Abstract

The aim of this study was to investigate clinical and laboratory findings of 12 g/kg and 18 g/kg of glucoseinduced different phases of experimental ruminal acidosis. The materials of the study were consisted 12 healthy rams ages between 2-3 and 51-62 kg of weight. Rams were divided into two groups. In the first group of 12 g/kg BW and the second 18 g/kg BW glucose were given orally for created ruminal acidosis. Loss of appetite, teeth grinding, groaning and forming a soft consistency stool or diarrhea were observed in acidotic sheep. Increased body temperature and pulse frequency, respiratory frequency, were not changed while rumen movements decreased. In the first group hematocrit value (only in 15 hours) and total white blood cell count were increased (p<0.05) meanwhile erythrocyte count, hematocrit value, hemoglobin concentration and total white blood cell count were increased significantly (p<0.05) in second group. Although in the both groups serum Na and Cl concentrations increased (p<0.05) while the concentration of K was found to decreased (p<0.05). Decreased were detected occurred in pH of rumen contents and statistical differences were determined when compared between two groups in 6., 9., 24., 32., 48. and 72. hours (respectively p<0.01, p<0.05, p<0.01, p<0.05, p<0.01, p<0.05). As while the rate of acetate were increased, propionate and butyrate rations decreased. In addition to increasing of glucose dose affects the rate of acetate (respectively in 2., 6. and 12. hours p<0.01, p<0.01, p<0.05) and propionate rations (in 2., 6. and 48. hours respectively p<0.01, p<0.01, p<0.05) but for butyrate (p>0.05) did not affected. As a result, evaluation of clinical and laboratory findings in ruminal acidotic animals those finding must be consideration for determination of prognosis and treatment planning was concluded

Özet

Bu araştırmada 12 g/kg ve 18 g/kg glikoz ile oluşturulan ruminal asidozisin farklı safhalarındaki klinik ve laboratuvar bulguların araştırılması amaçlanmıştır. Çalışmanın materyalini 2-3 yaşlarda, 51-62 kg canlı ağırlığında 12 adet sağlıklı koç oluşturdu. Koçlar iki gruba ayrıldı. 1. gruptakilere 12 g/kg CA, ikinci gruptakilere ise 18 g/kg CA dozunda glikoz oral yolla verilerek ruminal asidozis oluşturuldu. Ruminal asidozisli hayvanlarda iştahsızlık, diş gıcırdatma, inleme ve yumuşak kıvamlı dışkı veya ishalin şekillendiği gözlendi. Vücut ısısı ve nabız sayısının arttığı, solunum sayısının etkilenmediği, rumen hareketleri sayısının ise azaldığı saptandı. 1. grupta hematokrit değer (sadece 15. saatte) ile total lökosit sayısında artış (p

🔖

Cite This Article

ŞİMŞEK, A., SEKİN, S. (2015). Investigation of Hematological and Biochemical Parameters, Clinical Findings and Rumen Content in The Different Phases of Experimental Ruminal Acidosis in Sheep. Van Veterinary Journal, Cilt: 26 - Sayı: 2, 77–85. https://ajindex.com/articles/32686

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Ahrens FA (1967). Histamine, lactic acid, and hypertonicity as factors in the development of ruminitis in cattle. Am J Vet Res, 28, 1335–1342.
  2. Allen MS (1997). Relationship between fermentation acid production in the Rumen and the requirement for physically effective fiber. J Dairy Sci, 80, 1447-1462.
  3. Anonim (2011). Ruminal acidosis-aetiopathogenesis, prevention and treatment. http://www.dairyaustralia.com.au, erişim tarihi:15.02.2011.
  4. Andersen PH, Hesselholt M, Jarlov N (1994). Endotoxin and arachidonic acid metabolites in portal, hepatic and arterial blood of cattle with acute ruminal acidosis. Acta Vet Scand, 35, 223-234.
  5. Aytuğ CN, Alaçam E, Görgül S, Tuncer ŞD, Gökçen H, Yılmaz K (1991). Sığır Hastalıkları, 2. Baskı,
  6. Tümvet Ltd. Şti, Teknografik Matbaası, İstanbul.
  7. Bal MA (2008). Ruminantlarda Sindirim. In: Dukes Veteriner Fizyoloji. Yıldız S (Çeviri Ed), 439-474, 12. Baskı,
  8. Medipres Matbaacılık Ltd Şti, Malatya. Bramley E (2004). Ruminal acidosis in Southern Australian dairy cattle. Doctoral Thesis, Faculty of Veterinary Science, University of Sydney. Braun U, Rihs T, Schefer U (1992). Ruminal lactic acidosis in sheep and goats. Vet Rec, 130:343-349.
  9. Brossard L, Martin C, Michalet Doreau B (2003). Ruminal fermentative parameters and blood acido-basic balance changes during the onset and recovery of induced latent acidosis in sheep. Anim Res, 52, 513530. Brown MS, Hallford DM, Galyean ML, Krehbiel CR, Duff G (1999). Effect of ruminal glucose infusion on dry matter intake, urinary nitrogen composition, and serum metabolite and hormone profiles in Ewes. J Anim Sci, 77, 3068-3076.
  10. Cakala S, Brokowski T, Alybrycht A (1974). Rumen acidosis in sheep induced by different doses of saccharose. Pol Arch Weter, 17, 117-130.
  11. Cao GR, English PB, Flippich LJ, Inglish S (1987). Experimentally induced lactic acidosis in the goat. Aust Vet J, 64(12), 367-370.
  12. Choudri PC, Randhawa S, Sand Mishra SK (1980). Effect of lactic acidosis on electrolyte changes in blood and rumen liqour in buffalo calves. Zbl Vet Med, 27A, 358-363.
  13. Çelik MY (2011).
  14. Biyoistatistik, Bilimsel Araştırma, SPSS. Dicle Üniversitesi,
  15. Diyarbakır. Dirksen G (1970). Acidosis. In: Proc. International Symposium on Physiology of Digestion and Metabolism in The Ruminant. Phillipson AT (Ed), 612-625, Proc. International Symposium on Physiology of Digestion and Metabolism in The Ruminant. Oriel Pres, Newcastle, UK. Dirksen G (1989). Rumen function and disorders related to production disease. VII. Int Conf Dis