AI Summary & Key Takeaways
AI InsightConclusion: It is postulated that intestinal ischaemia may be of more importance in the development of abdominal pain in carcinoid tumors than that has generally been accepted, and that it is a result of the functional and structural changes in the mesenteric blood vessels, caused by substances secreted by the carcinoid tumor.
📌 3 Key Takeaways
Abstract
Background: Carcinoid tumors are rare, slow-growing neuroendocrine neoplasms that often are indolent and may not become clinically apparent until there has been metastatic spread or evidence of carcinoid syndrome. Case report: A 44-year old man who presented to our clinic with chronic crampy left lower quadrant pain, mass and severe anemia had a history of previous cancer operation from the left colon. The MR scan demonstrated a calcified mesenteric mass sized 12*8*10 cm, with surrounding left colon mesenteric infiltration. The liver was normal. A case of ischaemic ileal necrosis associated with elastic vascular sclerosing substances secreted by mesenteric metastases of an ileal carcinoid tumor is presented here. Conclusion: It is postulated that intestinal ischaemia may be of more importance in the development of abdominal pain in carcinoid tumors than that has generally been accepted, and that it is a result of the functional and structural changes in the mesenteric blood vessels, caused by substances secreted by the carcinoid tumor.
Özet
Karsinoid tümörler seyrek rastlanan, yavaş büyüyen nöroendokrin tümörler olup metastatik yayılım yapmadığı veya karsinoid sendrom gelişmediği takdirde klinik olarak belirti vermezler. Sol kolon kanseri nedeniyle ameliyat öyküsü bulunan 44 yaşında erkek hasta kliniğimize kronik sol alt kadran ağrısı, kitle ve anemi nedeniyle başvurmuştur. Magnetik rezonans bulgularında kolon mezenteriyle çevrelenmiş yaklaşık 12x8x10 cm boyutlarında kalsifiye kitle saptanmıştır. İleal karsinoid tümörün mezenterik metastazları tarafından salgılanan elastik vasküler sklerozan maddelere bağlı gelişen iskemik ileal nekroz olgusu sunulmuştur. Sonuç: Karsinoid tümörler nedeniyle oluşan intestinal iskemiye bağlı abdominal ağrılar önemsenmelidir. Bu ağrıların nedeni karsinoid tümörler tarafından salgılanan ürünler nedeniyle mezenterik damarlarda oluşan yapısal ve fonksiyonel değişikliklerdir.