Journals / Ulusal Cerrahi Dergisi / 2016 / Cilt: 32 - Sayı: 2

Incidental gallbladder cancers: Our clinical experience and review of the literature

İnsidental safra kesesi kanserleri: Klinik deneyimimiz ve literatürün gözden geçirilmesi

Pages
107–110
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The relatively low rates that have been reported in our population may be due to geographical differences and problems in study design.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Gallbladder carcinomas are rare and aggressive neoplasms.
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Key Findings & Data:We aimed to evaluate incidental gallbladder cancers in our clinic, in terms of patients' demographics, diagnosis, treatment and follow-up, and compared our results with the literature.Material and Methods: Patients who underwent laparoscopic cholecystectomy in the last 9 years were retrospectively reviewed, and features of the patients diagnosed with gallbladder cancer after histopathological evaluation were further evaluated.Results: Thirteen patients were female and two were male.
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Conclusion & Impact:The relatively low rates that have been reported in our population may be due to geographical differences and problems in study design.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Gallbladder carcinomas are rare and aggressive neoplasms. They are usually advanced at the time of diagnosis. We aimed to evaluate incidental gallbladder cancers in our clinic, in terms of patients' demographics, diagnosis, treatment and follow-up, and compared our results with the literature.Material and Methods: Patients who underwent laparoscopic cholecystectomy in the last 9 years were retrospectively reviewed, and features of the patients diagnosed with gallbladder cancer after histopathological evaluation were further evaluated.Results: Thirteen patients were female and two were male. The mean age was 67 years. Additional treatment was applied in seven patients. All patients were operated on laparoscopically, with conversion to open surgery in four patients. The rate of incidental gallbladder cancer was 0.17% in our patients. Survival rates were found to be 22.2% in patients who had been operated at least 5 years ago.Conclusion: Surgery is the only curative treatment in gallbladder cancers; however, they are usually at advanced stages at the time of diagnosis. In incidental gallbladder cancers, survival can be prolonged with appropriate treatment models if they are identified at early stages. The relatively low rates that have been reported in our population may be due to geographical differences and problems in study design.

Özet

Amaç: Safra kesesi kanserleri nadir görülen ve agresif seyirli kanserlerdir. Tanı aldıklarında genellikle ileri evrelerdedir. Kliniğimizde rastladığımız insidental safra kesesi kanserlerini hasta özellikleri, tanı, tedavi ve takip açısından incelemeyi amaçladık ve ulaştığımız sonuçları literatürle karşılaştırdık.Gereç ve Yöntemler: Dokuz yıllık süre içerisinde laparoskopik kolesistektomi yapılan hastaların dosyaları geriye dönük olarak incelendi ve postoperatif histopatolojik inceleme ile kanser tanısı alan hastaların özellikleri değerlendirildi.Bulgular: Hastaların 13 tanesi kadın, 2 tanesi erkekti, yaş ortalamaları 67 olarak hesaplandı. Yedi hastaya postoperatif dönemde ek tedavi uygulandı. Tüm ameliyatlara laparoskopik yöntemle başlandı, 4 hastada açık olarak tamamlandı. İnsidental safra kesesi kanseri %0,17 olarak saptandı. Ameliyatının üzerinden en az 5 yıl geçmiş ve ulaşılabilen hastalarda sağkalımın %22,2 olduğu görüldü.Sonuç: Safra kesesi kanserlerinde tek küratif tedavi yöntemi cerrahidir ancak tanı aldıklarında genellikle ileri evrededirler. İnsidental safra kesesi kanserleri erken evre olduklarında uygun tedavi ile hastaların sağkalımı uzatılabilir. Ülkemizden bildirilen düşük oranların altında yatan sebep coğrafi farklılık ve çalışma dizaynındaki sorunlar olabilir.

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Cite This Article

DÜZKÖYLÜ, Y., BEKTAŞ, H., KOZLUKLU, Z. D. (2016). Incidental gallbladder cancers: Our clinical experience and review of the literature. Ulusal Cerrahi Dergisi, Cilt: 32 - Sayı: 2, 107–110. https://ajindex.com/articles/325630

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