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Journals / Ulusal Cerrahi Dergisi / 2009 / Cilt: 25 - Sayı: 1

Efficacy of clinoptilolite on hepatic parenchymal bleeding

Karaciğer parankim kanamasının önlenmesinde Clinoptilolite'in etkinliği

Erhan AYŞAN
Hasan BEKTAŞ
Arslan KAYGUSUZ
Gülben Erdem HUQ
Pages
7–10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinoptilolite is not effective on hepatic parenchymal bleeding.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: Hepatic bleeding following abdominal trauma and hepatic surgery is a serious problem.
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Key Findings & Data:Materials and Methods: Hepatic resection model was performed on 20 Wistar albino female rats.
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Conclusion & Impact:Clinoptilolite is not effective on hepatic parenchymal bleeding.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Karaciğer · Sıçan · Wistar

Abstract

Purpose: Hepatic bleeding following abdominal trauma and hepatic surgery is a serious problem. Aim of this research is to evaluate of clinoptilolite on hepatic parenchymal bleeding. Materials and Methods: Hepatic resection model was performed on 20 Wistar albino female rats. The efficacy of hemostasis with clinoptilolite has been evaluated through the comparison of perioperative bleeding amount and preoperative and postoperative hematocrit levels. Results: Peroperative bleeding amounts were 0.3ml (0.18-0.4) in the control group, 0.2ml (0.1-0.3) in the clinoptilolite group (p>0.05). Preoperative and postoperative hematocrit differences were 9 (4- 12.3) in control group and 8 (4.75-10.5) in clinoptilolite group (p>0.05). Conclusions: Clinoptilolite decreases peroperative and postoperative hepatic parenchymal bleeding, but is not statistically significant. Clinoptilolite is not effective on hepatic parenchymal bleeding.

Özet

Amaç: Karaciğer parankim kanamasının önlenmesinde clinoptilolite'in etkinliğini değerlendirmek. Durum Değerlendirmesi: Karaciğer parankim kanaması travmalarda ve karaciğere yönelik cerrahi girişimlerde önemli bir sorundur. Yöntem: Yirmi adet Wistar albino dişi sıçan üzerinde çalışıldı. Karaciğer laserasyon modeli oluşturulduktan sonra bu bölge kontrol grubundaki sıçanlarda (n=10) %0.9 NaCl emdirilmiş gazlı bezlerle, çalışma grubundaki sıçanlarda ise (n=10) 1g clinoptilolite emdirilmiş gazlı bezlerle 3dk. süreyle komprese edildi. Peroperatif kanama miktarları mililitre olarak ölçülerek, postoperatif kanama miktarları ise hematokrit değerleri karşılaştırılarak belirlendi. Bulgular: Kontrol grubunda peroperatif kanama miktarı 0.3ml (0.18-0.4) iken, clinoptilolite grubunda 0.2ml (0.1-0.3) idi (p>0.05). Grupların preoperatif/postoperatif hematokrit farkları karşılaştırıldığındaysa bu değer, kontrol grubunda 9 (4-12.3) iken, clinoptilolite grubunda 8 (4.75-10.5) idi (p>0.05). Sonuç: Clinoptilolite peroperatif ve postoperatif kanama miktarlarında bir miktar azalmaya neden olmaktadır ancak bu istatistiksel olarak anlamlı düzeyde değildir. Clinoptilolite, karaciğer parankim kanamasının önlenmesi ya da azaltılmasında etkin değildir

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Cite This Article

AYŞAN, E., BEKTAŞ, H., KAYGUSUZ, A., HUQ, G. E. (2009). Efficacy of clinoptilolite on hepatic parenchymal bleeding. Ulusal Cerrahi Dergisi, Cilt: 25 - Sayı: 1, 7–10. https://ajindex.com/articles/325519

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