Journals / Ulusal Cerrahi Dergisi / 2015 / Cilt: 31 - Sayı: 4

How to approach phyllodes tumors of the breast?

Memenin filloides tümörlerinde tedavi yaklaşımları nasıl olmalı?

Pages
197–201
DOI
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Due to high rates of local recurrence and potential for malignancy, preoperative diagnosis and accurate management are important

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Objective & Hypothesis:Objective: Phyllodes tumor of the breast is a rare fibroepithelial breast tumor that comprise 0.3-0.9% of primary breast neoplasms.
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Key Findings & Data:In this study, we aimed to present clinicopathologic symptoms of our patients along with their treatment modality.Material and Methods: Clinicopathologic properties and treatment modality of 20 phyllodes tumor patients who underwent surgery between January 2008 and January 2013 were retrospectively evaluated.Results: Median patient age was 47 years .
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Conclusion & Impact:Due to high rates of local recurrence and potential for malignancy, preoperative diagnosis and accurate management are important
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Phyllodes tumor of the breast is a rare fibroepithelial breast tumor that comprise 0.3-0.9% of primary breast neoplasms. In this study, we aimed to present clinicopathologic symptoms of our patients along with their treatment modality.Material and Methods: Clinicopathologic properties and treatment modality of 20 phyllodes tumor patients who underwent surgery between January 2008 and January 2013 were retrospectively evaluated.Results: Median patient age was 47 years . Fine-needle aspiration biopsy was applied to 19 patients. Biopsy results were reported as suspicious in four, malignant in three, benign in 11, and as non-diagnostic in one patient. Final histopathology reports revealed two benign, one malignant and one borderline tumor out of the four patients with suspicious findings on fine needle aspiration biopsy; all patients with malignant cytology had malignancy. There were two borderline and nine benign lesions within the benign biopsy group. Sixteen patients underwent segmental mastectomy, four patients underwent mastectomy with/without axillary dissection. The median tumor size was 6 cm. Histopathologically, 11 (55%) tumors were benign, 5 (25%) were borderline, and 4 (20%) were malignant. Two of the four patients with malignancy underwent radiotherapy and chemotherapy, and one patient only received chemotherapy as adjuvant treatment.Conclusion: Phyllodes tumors are rare, mix-type breast tumors. Due to high rates of local recurrence and potential for malignancy, preoperative diagnosis and accurate management are important

Özet

Amaç: Memenin filloides tümörü, tüm primer meme neoplazmlarının %0,3-0,9'unu oluşturan, nadir görülen fibroepitelyal bir meme tümörüdür. Bu çalışmada filloides tanılı hastalarımızın klinikopatolojik bulgularını ve tedavi yaklaşımımızı sunmayı amaçladık.Gereç ve Yöntemler: Ocak 2008-Ocak 2013 tarihleri arasında ameliyat ettiğimiz filloides tanılı 20 hastanın klinikopatolojik özellikleri ve tedavi yaklaşımları retrospektif olarak değerlendirilmiştir.Bulgular: Hastaların ortanca yaşı 47 olarak saptanmıştır. Hastalardan 19 tanesine ince iğne aspirasyon biyopsisi (İİAB) uygulanmıştır. İİAB'lerin 4'ü kuşkulu sitoloji, 3'ü malign sitoloji, 11'i benign sitoloji ve 1'i de nondiagnostik olarak raporlandı. Hastaların kesin histopatolojik sonucu; kuşkulu sitolojilerin 2'si benign, 1'i malign, 1'i de borderline olarak, malign sitolojilerin hepsi malign, benign sitolojilerin de 2'si borderline 9'u benign olarak bildirildi. Cerrahi uygulanan hastalardan; 16'sına geniş kitle eksizyonu (segmental mastektomi), 4'üne de mastektomi (± aksiller diseksiyon) uygulanmıştır. Ortanca tümör boyutu 6 cm'dir. Histopatolojik olarak tümörlerin 11'i (%55) benign, 5'i (%25) borderline, 4'ü (%20) malign olarak sınıflandırılmıştır. Cerrahi sonrası adjuvan olarak 4 malign hastadan 2'sine radyoterapi ve kemoterapi,1'ine sadece kemoterapi verilmiştir.Sonuç: Filloides tümörler nadir görülen mikst meme tümörleridir. Lokal rekürrens oranlarının fazlalığı ve malign potansiyelleri nedeniyle preoperatif tanı ve dikkatli yönetim önemlidir

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Cite This Article

ACAR, T., TARCAN, E., HACIYANLI, M., KAMER, E., PEŞKERSOY, M., YİĞİT, S., GÜR, E. Ö., CİN, N., AKDER, A. S., TATAR, F. (2015). How to approach phyllodes tumors of the breast?. Ulusal Cerrahi Dergisi, Cilt: 31 - Sayı: 4, 197–201. https://ajindex.com/articles/325371

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