Journals / Ulusal Cerrahi Dergisi / 2016 / Cilt: 32 - Sayı: 1

Sentinel lymph node biopsy under fluorescent indocyanin green guidance: Initial experience

Floresan ışıkla görüntülenen indosiyanin yeşili rehberliğinde sentinel lenf nodu biyopsisi: İlk deneyimimiz

Pages
50–53
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no complication during and after the operation related to the method.Conclusion: According to our limited experience, sentinel lymph node biopsy under fluorescent indocyanine green guidance, which has an advantage of simultaneous visualization, is technically feasible.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Sentinel lymph node biopsy can be applied by using either blue dye or radionuclide method or both in breast cancer.
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Key Findings & Data:The median number of excised sentinel lymph node was 2 .
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Conclusion & Impact:There was no complication during and after the operation related to the method.Conclusion: According to our limited experience, sentinel lymph node biopsy under fluorescent indocyanine green guidance, which has an advantage of simultaneous visualization, is technically feasible.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Sentinel lymph node biopsy can be applied by using either blue dye or radionuclide method or both in breast cancer. Fluorescent imaging with indocyanine green is a new defined method. This study evaluates the applicability of sentinel lymph node biopsy via fluorescent indocyanine green.Material and Methods: IC-VIEW (Pulsion Medical Systems AG, Munich, Germany) infrared visualization system was used for imaging. Two mL of indocyanine green was injected to visualize sentinel lymph nodes. After injection, subcutaneous lymphatics were traced and sentinel lymph nodes were found with simultaneous imaging. Sentinel lymph nodes were excised under fluorescent light guidance, and excised lymph nodes were examined histopathologically. Patients with sentinel lymph node metastases underwent axillary dissection.Results: Four patients with sentinel lymph node biopsy due to breast cancer were included in the study. Sentinel lymph nodes were visualized with indocyanine green in all patients. The median number of excised sentinel lymph node was 2 . Two patients with lymph node metastasis underwent axillary dissection. No metastasis was detected in lymph nodes other than the sentinel nodes in patients with axillary dissection. There was no complication during and after the operation related to the method.Conclusion: According to our limited experience, sentinel lymph node biopsy under fluorescent indocyanine green guidance, which has an advantage of simultaneous visualization, is technically feasible.

Özet

bine edilerek yapılabilmektedir. İndosiyanin yeşili kullanılarak yapılan floresan görüntüleme ise yeni tanımlanan bir metottur. Bu çalışma floresan ışıkla görüntülenen indosiyanin yeşili rehberliğinde yapılan sentinel lenf nodu biyopsisinin uygulanabilirliğini değerlendirmektedir.Gereç ve Yöntemler: Görüntüler için kızıl ötesini gösteren IC-VIEW sistemi (Pulsion Medical Systems AG, Münih, Almanya) kullanıldı. Sentinel lenf nodlarının görüntülenmesi için 2 mL indosiyanin yeşili enjeksiyonu yapılİstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İstanbul, Türkiyedı. Enjeksiyon sonrası eş zamanlı görüntü ile subkutan lenfatikler takip edilerek sentinel lenf nodlarına ulaşıldı. Floresan ışık rehberliğinde sentinel lenf nodları eksize edilerek histopatolojik inceleme yapıldı. Sentinel lenf nodunda metastaz saptanan hastalara aksiller diseksiyon yapıldı.Bulgular: Çalışmada meme kanseri nedeniyle sentinel lenf nodu biyopsisi yapılan dört hasta yer aldı. İndosiyanin yeşili ile tüm hastalarda sentinel lenf nodları görüntülendi. İndosiyanin yeşili ile eksize edilen ortanca sentinel lenf nodu sayısı 2 olarak bulundu. Lenf nodu metastazı saptanan iki hastaya aksiller diseksiyon yapıldı. Aksiller diseksiyon yapılan hastaların sentinel dışındaki lenf nodlarında metastaz görülmedi. Ameliyat sırasında ve sonrasında metoda bağlı komplikasyon görülmedi.Sonuç: Sınırlı tecrübemize göre eş zamanlı görüntüleme avantajına sahip olan indosiyanin yeşili rehberliğinde yapılan sentinel lenf nodu biyopsisi teknik olarak uygulanabilir görülmektedir.

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Cite This Article

AYDOĞAN, F., ARIKAN, A. E., AYTAÇ, E., VELİDEDEOĞLU, M., YILMAZ, M. H., SAĞER, M. S., ÇELİK, V., URAS, C. (2016). Sentinel lymph node biopsy under fluorescent indocyanin green guidance: Initial experience. Ulusal Cerrahi Dergisi, Cilt: 32 - Sayı: 1, 50–53. https://ajindex.com/articles/325333

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