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Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2009 / Cilt: 15 - Sayı: 6

Siyanoakrilat yardımlı arteriyotomi kapama tekniğinin konvansiyonel kapama tekniği ile karşılaştırılması

Comparison of cyanoacrylate-assisted arteriotomy closure with conventional closure technique

Ömer Faik ERSOY
Hüseyin Ayhan KAYAOĞLU
Alper ÇELİK
NAMIK ÖZKAN
Neşe LORTLAR
Sana ÖMEROĞLU
Pages
535–540
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It also does not lead to increased myointimal hyperplasia.

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND We aimed to compare conventional suture closure of arteriotomy with N-butyl-cyanoacrylate-assisted suture closure.
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Key Findings & Data:In the first group, arteriotomy was closed by 3 stitches with 45° between each and in the second by two stitches with 0.1 ml (12-12.5 mg) cyanoacrylate.
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Conclusion & Impact:It also does not lead to increased myointimal hyperplasia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Aort · abdominal · Kanama

Abstract

BACKGROUND We aimed to compare conventional suture closure of arteriotomy with N-butyl-cyanoacrylate-assisted suture closure. METHODS Forty Wistar rats were randomly divided into two groups. Standard arteriotomy was performed to the abdominal aorta through a midline incision. In the first group, arteriotomy was closed by 3 stitches with 45° between each and in the second by two stitches with 0.1 ml (12-12.5 mg) cyanoacrylate. Amount of blood loss, operation time and severity of myointimal hyperplasia by immunohistochemistry on aorta segments were measured on postoperative days 7 and 30. RESULTS Mean anastomotic time was 13.5±1.64 in the first and 13.0±1.75 min in the second group (p=0.356). Operation time was 23.45±3.63 in the control and 21.0±3.09 min in the second group (p=0.027). Mean amount of bleeding was 473.75± 260.5 in the first and 327.5± 155.36 μl in the second group (p=0.037). Intimal thickness on the 7th day was 80.62±7.92 in the first and 83.24±3.42 μm in the second group, and on the 30th day was 81.64±5.11 in the first and 88.77±11.03 μm in the second group. The early and late intimal thicknesses were similar (p=0.35 and 0.87, respectively). CONCLUSION Reconstruction of arteriotomies with fewer sutures in combination with cyanoacrylate is a safe method associated with less blood loss and shorter operation time. It also does not lead to increased myointimal hyperplasia.

Özet

AMAÇ Arteriyotomi sonrası, konvansiyonel dikiş tekniği ile n-bütil-2-siyanoakrilat yardımlı kapama tekniği karşılaştırıldı. GEREÇ VE YÖNTEM Kırk adet Wistar sıçan randomize olarak 2 gruba ayrıldı. Orta hat kesisiyle abdominal aortaya standart arteriyotomi uygulandı. Arteriyotomi, birinci grupta aralarında 45° açıyla 3 adet; ikinci grupta ise 60° açıyla 2 adet dikişle kapatıldı. İkinci gruba 0,1 ml (12-12,5 mg) siyanoakrilat uygulandı. Operasyon zamanı, kanama miktarı ve aortanın çıkarılan anastomotik segmentinde cerrahi sonrası 7. ve 30. günlerde immünohistokimyasal olarak miyointimal hiperplazinin şiddeti değerlendirildi. BULGULAR Ortalama anastomoz zamanı 1. grupta 13,5±1,64 dk, 2. grupta 13,0±1,75 dk idi (p=0,356). Ameliyat süresi kontrol grubunda 23,45±3,63 dk, tedavi grubunda 21,0±3,09 dk olarak saptandı (p=0,027). Ortalama kanama miktarı 1. grupta 473,75±260,5 μl, 2. grupta 327,5±155,36 μl idi (p=0,037). Yedinci günde yapılan ölçümde intima kalınlığı 1. grupta 80,62±7,92 μm, 2. grupta 83,24±3,42 μm; 30. günde 1. grupta 81,64±5,11 μm, 2. grupta 88,77±11,03 μm olarak bulundu. Erken ve geç ölçümlerde intima kalınlıkları benzer düzeylerdeydi (sırasıyla p=0,35 ve p=0,87). SONUÇ Arteriyotomilerin daha az dikişle, n-bütil-2-siyanoakrilat birleşimiyle rekonstrüksiyonu, daha az kanama ve daha kısa ameliyat süreleri ile seyreden güvenilir bir yöntemdir. Ayrıca, miyointimal hiperplazide artışa neden olmamıştır.

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Cite This Article

ERSOY, Ö. F., KAYAOĞLU, H. A., ÇELİK, A., ÖZKAN, N., LORTLAR, N., ÖMEROĞLU, S. (2009). Siyanoakrilat yardımlı arteriyotomi kapama tekniğinin konvansiyonel kapama tekniği ile karşılaştırılması. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 15 - Sayı: 6, 535–540. https://ajindex.com/articles/324613

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