Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2010 / Cilt: 16 - Sayı: 1

Prognostic factors for hospital mortality in patients with acute mesenteric ischemia who undergo intestinal resection due to necrosis

Nekroz nedeniyle bağırsak rezeksiyonu uygulanan akut mezenterik iskemili olgularda hastane mortalitesi için prognostik faktörler

Pages
63–70
DOI
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A total of 67 patients (34 female, overall mean age 66 years) were evaluated in the study.

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND The purpose of this study was to review our experience in patients with acute mesenteric ischemia (AMI) and to identify prognostic factors associated with hospital mortality.
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Key Findings & Data:A total of 67 patients (34 female, overall mean age 66 years) were evaluated in the study.
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Conclusion & Impact:Early evaluation in high-risk patients and resection for necrosed intestinal segments as soon as possible prior to sepsis may reduce the hospital mortality rate.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND The purpose of this study was to review our experience in patients with acute mesenteric ischemia (AMI) and to identify prognostic factors associated with hospital mortality. METHODS Clinical data of patients with AMI were reviewed and analyzed retrospectively. A total of 67 patients (34 female, overall mean age 66 years) were evaluated in the study. RESULTS Small bowel necrosis was detected in all patients, while colonic involvement was present in 21 (31.3%). Necrosed small bowels were resected in 59 (88%) in the first intervention. Embolectomy was also performed in 2 (3%) of these cases. Anastomosis was established in 22 (32.8%). Secondlook operation was performed in 31 (46.3%) and primary resection and re-resection were performed in 8 (11.9%) and 11 (16.4%) patients, respectively. Hospital mortality rate was 56.7% (n=38). Logistic regression analysis showed prolonged symptom duration (>24h) (p=0.000), sepsis (p=0.022) and colonic necrosis accompanied with small bowel necrosis (p=0.002) as the independent prognostic factors in hospital mortality. CONCLUSION AMI has a high hospital mortality rate due to late diagnosis and sepsis. Another risk factor is colonic involvement. Early evaluation in high-risk patients and resection for necrosed intestinal segments as soon as possible prior to sepsis may reduce the hospital mortality rate.

Özet

MAÇ Nekroz nedeniyle bağırsak rezeksiyonu yapılan akut mezenterik iskemili (AMİ) hastalardaki deneyimlerimiz sunuldu ve hastane mortalitesi ile ilgili prognostik faktörler değerlendirildi. GEREÇ VE YÖNTEM AMİ’li hastaların klinik kayıtları gözden geçirildi ve retrospektif olarak analiz edildi. Bu çalışmada, 67 hasta (34’ü kadın ve ortalama yaş 66) incelendi. BULGULAR Hastaların tümünde ince bağırsak nekrozu, 21’inde (%32,3) kolon tutulumu belirlendi. Olguların 59’unda (%88) nekrotik ince bağırsaklar ilk girişim sırasında rezeke edildi. Bu hastalardan 2’sine (%3) embolektomi de uygulandı. Olguların 22’sine (%32,8) anastomoz yapıldı. Olguların 31’ine (%46,3) second look operasyon yapılarak 8’ine (%11,9) primer rezeksiyon, 11’ine (%16,3) re-rezeksiyon uygulandı. Hastane mortalite oranı %56,7 (n=38) bulundu. Lojistik regresyon testinde semptom süresinin >24 saat olmasının (p=0,000), başvuru sırasında sepsis saptanmasının (p=0,022) ve ince bağırsak nekrozuna kolon tutulumunun da eklenmiş olmasının (p=0,002) hastane mortalitesi için bağımsız prognostik faktörler olduğu gösterildi. SONUÇ Geç tanı konması ve sepsis nedeniyle AMİ’de hastane mortalitesi oranı yüksektir. Diğer bir risk faktörü kolon tutulumudur. Yüksek riskli hastalara erken ve agresif yaklaşım ve sepsis gelişmeden önce nekrotik bağırsakların olabildiğince erken rezeke edilmesi hastane mortalite oranlarını düşürebilir.

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Cite This Article

ÜNALP, H. R., ATAHAN, K., KAMER, E., YAŞA, H., TARCAN, E., ÖNAL, M. A. (2010). Prognostic factors for hospital mortality in patients with acute mesenteric ischemia who undergo intestinal resection due to necrosis. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 16 - Sayı: 1, 63–70. https://ajindex.com/articles/324552

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