Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2010 / Cilt: 16 - Sayı: 3

Çoklu travmalarda koagülopati

Coagulopathy in multiple traumas

Pages
198–202
DOI
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CONCLUSION The coagulation parameters were observed to diverge in patients with head trauma, but in cases with head injuries accompanying other local traumas, more coagulation parameters became abnormal.

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Objective & Hypothesis:BACKGROUND This study aimed at analyzing the effect on coagulation of head trauma and other local traumas in patients exposed to multiple traumas in the early stage, and also the relations of Glasgow Coma Scale (GCS) and Injury Severity Score (ISS) with coagulation parameters in these patients.
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Key Findings & Data:METHODS Fifty consecutive patients (9 women, 41 men) with multiple traumas were included in this study.
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Conclusion & Impact:CONCLUSION The coagulation parameters were observed to diverge in patients with head trauma, but in cases with head injuries accompanying other local traumas, more coagulation parameters became abnormal.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND This study aimed at analyzing the effect on coagulation of head trauma and other local traumas in patients exposed to multiple traumas in the early stage, and also the relations of Glasgow Coma Scale (GCS) and Injury Severity Score (ISS) with coagulation parameters in these patients. METHODS Fifty consecutive patients (9 women, 41 men) with multiple traumas were included in this study. The GCS, ISS and coagulation parameter levels were measured. Presence of a correlation between GCS and ISS with coagulation parameters was analyzed. Patients exposed to multiple traumas were assessed in four categories as the patients with no significant traumas (A), only head traumas (B), head trauma and other local traumas (C), and no head traumas but other local traumas (D). RESULTS A marked relationship was found between ISS and international normalized ratio (INR), activated partial thromboplastin time (aPTT), D-dimer, fibrin degradation product (FDP), antithrombin (AT), and fibrinogen (p<0.05). There was a statistically significant difference between Group C and the other groups in INR, D-dimer, fibrinogen, aPTT, and AT parameters (p<0.05). There was also a statistically significant difference between the groups with and without head trauma in INR, D-dimer and fibrinogen (p<0.05). CONCLUSION The coagulation parameters were observed to diverge in patients with head trauma, but in cases with head injuries accompanying other local traumas, more coagulation parameters became abnormal.

Özet

AMAÇ Erken dönemde genel vücut travmalı (GVT) hastalarda, kafa travmasının ve diğer bölge travmalarının koagülasyon üzerine etkisi ve bu hastalarda koagülasyon parametreleri ile Glaskow Koma Skoru (GCS) ve travma şiddet skoru (ISS) ilişkilerinin araştırılması amaçlandı. GEREÇ VE YÖNTEM Acil servise GVT ile başvuran, 50 hasta (9 kadın, 41 erkek) çalışmaya alındı. Hastaların GCS, ISS, koagülasyon parametreleri düzeyleri belirlendi. GCS, ISS ile koagülasyon parametreleri arasında korelasyon değerlendirildi. Hastalar; önemli bir travma tespit edilmeyen (A), sadece kafa travması olanlar (B), kafa travması ve diğer bölge travması olanlar (C), kafa travması olmayan ancak diğer bölge travmaları olanlar (D) olarak ayrıldı. BULGULAR ISS ile uluslararası normalize oranı (INR), aktif parsiyel tromboplastin zamanı (aPTT), D-dimer ve fibrin yıkım ürünleri (FDP) düzeyleri arasında pozitif, ISS ile antitrombin (AT) ve fibrinojen düzeyleri arasında negatif bir ilişki saptandı (p<0,05). C grubuyla diğer gruplardaki INR, D-dimer, fibrinojen, aPTT, AT parametreleri karşılaştırıldığında istatistiksel anlamlılık saptandı (p<0,05). Kafa travması olan ve olmayan gruplar arasındaki INR, D-dimer ve fibrinojen parametrelerinde istatistiksel anlamlılık saptandı (p<0,05). SONUÇ Kafa travması olan hastalarda koagülasyon parametrelerinin bozulduğu, ancak kafa travmasına diğer bölge travmaları eşlik ettiğinde koagülasyon parametrelerinin daha fazla anormalleştiği belirlendi.

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Cite This Article

TURTAY, M. G., KIRIMLIOĞLU, V., CEYLAN, C. (2010). Çoklu travmalarda koagülopati. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 16 - Sayı: 3, 198–202. https://ajindex.com/articles/324285

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