Forrest tip 2b duodenal ülserlerde profilaktik enjeksiyon tedavisi gereklidir

Objective & Hypothesis:Objective: To assess the effect of prophylactic injection therapy during the index gastroscopy on upper gastrointestinal bleeding due to Forrest type 2b duodenal ulcer.

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Key Findings & Data:Methods: The patients who were admitted with upper gastrointestinal bleeding and who had emergency gastroscopy between January 2004 and January 2011 were retrospectively recruited to the study.

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Conclusion & Impact:Conclusion: We recommend prophylactic injection therapy in patients with upper gastrointestinal bleeding who have Forrest type 2b duodenal ulcer.

🔬Design:Research Article

📍Scope:2004 Verileri

⚙️Variables:Domain Parameters

Abstract

Objective: To assess the effect of prophylactic injection therapy during the index gastroscopy on upper gastrointestinal bleeding due to Forrest type 2b duodenal ulcer. Methods: The patients who were admitted with upper gastrointestinal bleeding and who had emergency gastroscopy between January 2004 and January 2011 were retrospectively recruited to the study. Among those, the patients with Forrest type 2b duodenal ulcer were selected and divided into two groups. The patients in Group 1 had only diagnostic gastroscopy, whereas those in Group 2 had prophylactic injection therapy during the index gastroscopy. Results: Eighty seven patients were included to the study. There were 41 patients in Group 1 and 46 patients in Group 2. There was a significant difference in the incidence of rebleeding (26.8% versus 6.5%, p=0.017). The mortality rate was similar in both groups (9.7% versus 2.1%, p=0.184). Conclusion: We recommend prophylactic injection therapy in patients with upper gastrointestinal bleeding who have Forrest type 2b duodenal ulcer.

Özet

AMAÇ Bu çalışmada Forrest tip 2b duodenal ülserlerde ilk endos- kopi işlemi esnasında yapılan profilaktik enjeksiyon teda- visinin ülserin tekrar kanama oranı üzerine etkisinin belir- lenmesi amaçlandı. GEREÇ VE YÖNTEM Çalışmaya hastanemizde 2004-2011 yılları arasında üst gastrointestinal sistem kanaması nedeniyle yapılan acil endoskopilerinde Forrest tip 2b duodenal ülser belirlenmiş hastalar alındı. Olgular rastgele olmayan iki gruba ayrıldı. Birinci gruba yalnızca tanısal endoskopi yapılan hastalar ve ikinci gruba tanısal endoskopiye ek olarak profilaktik enjeksiyon tedavisi yapılan hastalar alındı. Çalışmadaki birincil sonuç ölçütleri yeniden kanama ve ölüm oranı idi. BULGULAR Çalışmaya 87 hasta alındı. Bunlardan 41’i birinci, 46’sı ikin- ci grupta idi. Tekrar kanama oranı açısından her iki grup ara- sında anlamlı fark saptanırken (%26,8 ve %6,5, p=0,017), ölüm oranı açısından iki grup arasında istatistiksel anlam taşıyan bir farklılık gözlenmedi (%9,5 ve %2,1, p>0,05). SONUÇ Yeniden kanama riskini anlamlı düzeyde azalttığı için, For- rest tip 2b duodenal ülserlerde profilaktik enjeksiyon teda- visi uygulanmalıdır.

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Cite This Article

ÖNER, O. Z., GÖNENÇ, M., KALAYCI, M. U., BOZKURT, M. A., KAPAN, S., ALIŞ, H. (2013). Forrest tip 2b duodenal ülserlerde profilaktik enjeksiyon tedavisi gereklidir. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 19 - Sayı: 1, 29–32. https://ajindex.com/articles/324136

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