Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2014 / Cilt: 20 - Sayı: 1

Hem otogreft hem de allogreft 4:1 oranında meşlendiğinde bile otohomogreftleme başarılı olabilir

Auto-/homografting can work well even if both autograft and allograft are meshed in 4:1 ratio

Pages
33–38
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The actual expansion rate was 43.7% of the predicted expansion rate.CONCLUSION: In this study, we demonstrated that the donor site morbidities were reduced and successful epithelialization was completed on the eighth day after using both autograft and allograft meshed with a 4:1 ratio.

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: Patients suffering major burns of more than 50% total burn surface area lack an adequate skin graft donor site to resurface extensive burn wounds and usually need widely meshed autografting and allografting.
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Key Findings & Data:Anything over the 3:1 expansion ratio is strongly associated with low graft take, poor or delayed epithelialization, and hypertrophic scarring.
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Conclusion & Impact:The actual expansion rate was 43.7% of the predicted expansion rate.CONCLUSION: In this study, we demonstrated that the donor site morbidities were reduced and successful epithelialization was completed on the eighth day after using both autograft and allograft meshed with a 4:1 ratio.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: Patients suffering major burns of more than 50% total burn surface area lack an adequate skin graft donor site to resurface extensive burn wounds and usually need widely meshed autografting and allografting. Anything over the 3:1 expansion ratio is strongly associated with low graft take, poor or delayed epithelialization, and hypertrophic scarring. METHODS: In this study, both autografts and allografts were expanded at a 4:1 ratio. We aimed to use skin grafts effectively and to decrease the morbidity due to graft harvesting. Nine patients with major burns were treated with this method. Graft gain ratio and percentage of actual expansion to predicted expansion were calculated.RESULTS: Ten auto-allografting procedures were performed on a mean of day 16. Graft take was over 95% successful. Five patients survived, and four patients died. The mean total burn surface area was 58.8% in patients who recovered, and 77.5% in the patients who died. The graft gain ratio was 74.8%. The actual expansion rate was 43.7% of the predicted expansion rate.CONCLUSION: In this study, we demonstrated that the donor site morbidities were reduced and successful epithelialization was completed on the eighth day after using both autograft and allograft meshed with a 4:1 ratio.

Özet

AMAÇ: Vücut yüzey alanının %50'sinden fazlasının yandığı majör yanıklı hastalarda geniş yanık alanlarının tedavisinde deri grefti donör alanları yetersiz kalır ve bu hastalar genellikle genişçe meşlenmiş otogreftleme ve allogreftlemeye ihtiyaç duyarlar. 3:1'in üzerindeki meşleme oranları kuvvetle az greft tutması, kötü veya gecikmiş epitelizasyon ve hipertrofik skar ile beraberlik gösterir. GEREÇ VE YÖNTEM: Bu çalışmada otogreftler ve allogreftler 4:1 oranında meşlendi. Deri greftlerini daha efektif kullanmayı ve greft alınmasına bağlı morbiditeyi azaltmayı amaçladık. Majör yanıklı 9 hasta bu yöntemle tedavi edildi. Greft kazanç oranları ve gerçek greft genişleme oranının beklenen genişleme oranına olan yüzdesi hesaplandı. BULGULAR: Ortalama 16. günde ve toplam 10 oto-allogreftleme ameliyatı gerçekleştirildi. Greft tutma oranı %95 idi. Beş hasta yaşamaya devam ederken 4 hasta çalışma esnasında hayatını kaybetti. Yaşayan hastalarda ortalama toplam vücut yanık alan yüzdesi %58.8 iken ölen hastalarda bu oran %77.5 idi. Greft kazanç oranı %74.8 oldu. Gerçek greft genişleme oranı beklenenin %43.7'si olarak bulundu. TARTIŞMA: Bu çalışmada, otogreftler ve allogreftler 4:1 oranında meşlendiğinde, donör alan morbiditesinin azaltıldığı ve 8. günde başarılı epitelizasyonun sağlandığı gösterilmiştir.

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Cite This Article

ŞAHİN, İ., ALHAN, D., NIŞANCI, M., ÖZER, F., IŞIK, S., IŞIK, S. (2014). Hem otogreft hem de allogreft 4:1 oranında meşlendiğinde bile otohomogreftleme başarılı olabilir. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 20 - Sayı: 1, 33–38. https://ajindex.com/articles/324089

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