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Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2016 / Cilt: 22 - Sayı: 6

Cinsiyet Fournier gangreni prognozuna etkili bir faktör değildir: Olgu-eşleme çalışması

Gender does not affect the prognosis of Fournier's gangrene: a case-matched study

Pınar SARKUT
ÖZGEN IŞIK
Ersin ÖZTÜRK
BARIŞ GÜLCÜ
İLKER ERCAN
Tuncay YILMAZLAR
Pages
541–544
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Overall mortality rate was 28.1% (18 of 64 patients).

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: Female gender is accepted as a poor prognostic factor for Fournier's gangrene (FG).
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Key Findings & Data:This case-matched study was designed to investigate the impact of gender on outcomes of FG.METHODS: Study patient data were retrieved from 120-patient, prospectively maintained database.
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Conclusion & Impact:Overall mortality rate was 28.1% (18 of 64 patients).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: Female gender is accepted as a poor prognostic factor for Fournier's gangrene (FG). However, there is a paucity of data in the literature regarding this matter. This case-matched study was designed to investigate the impact of gender on outcomes of FG.METHODS: Study patient data were retrieved from 120-patient, prospectively maintained database. Thirty-two female patients with FG were case-matched to 32 male patients based on symptom duration (days), FG severity index score, patient age, etiology, and presence of diabetes mellitus (DM) terms. Outcomes of FG were compared between the 2 groups.RESULTS: Median age was 57 years (range: 22-80 years), and 35 (54.7%) patients had DM. Patients underwent average of 3 debridement procedures (range: 1-9 debridements), and 15 (23.4%) received diverting stoma. Overall mortality rate was 28.1% (18 of 64 patients). Female gender was associated with widespread disease (p=0.009), increased need for consecutive debridements (p=0.005), prolonged length of intensive care unit stay (p=0.035), and increased requirement for split-thickness skin graft reconstruction (p=0.040). However, mortality rates were comparable between genders (p=0.264).CONCLUSION: FG is often more extensive in females and seems to be associated with anatomical features of female pelvis. However, female gender is not a factor affecting prognosis of patients with FG.

Özet

AMAÇ: Kadın cinsiyet Fournier gangreni (FG) için olumsuz bir prognostik faktör olarak görülmektedir. Ancak literatürde bu konuya özgün yeterli veri yoktur. Bu olgu-eşleme çalışması kadın cinsiyetin FG prognozuna etkisini incelemek için yapıldı. GEREÇ VE YÖNTEM: Çalışmaya alınan hastalar kliniğimizin 120 hastalık ileriye yönelik olarak tutulan veritabanından çekildi. Otuz iki kadın hasta aşağıdaki kriterler baz alınarak 32 erkek hastayla eşleştirildi: Semptom süresi, FG severity indeks (FGSI) skoru, hasta yaşı, etiyoloji ve eşlik eden diyabetes mellitus (DM) varlığı. Daha sonra iki grup hasta klinik sonuçlar açsından karşılaştırıldı. BULGULAR: Medyan yaş 57 (22-80) idi ve 35 (%54.7) hastada DM vardı. Hastalara ortalama 3 (1-9) debridman yapıldı ve 15 hastaya (%23.4) saptırıcı stoma açıldı. Mortalite oranı %28.1 (64'te 18 hasta) idi. Kadınlarda FG daha yaygındı (p=0.009), daha fazla debridmana ihtiyaç duyulmuştu (p=0.005), kadınlar yoğun bakım ünitesinde daha fazla oranda kalmıştı (p=0.035) ve kadınlarda split thickness skin graft (STSG) ile rekonstrüksiyon daha fazla oranda yapılmıştı (p=0.040), ancak mortalite oranları iki grup arasında benzerdi (p=0.264). TARTIŞMA: Fournier gangreni kadınlarda erkeklere

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Cite This Article

SARKUT, P., IŞIK, Ö., ÖZTÜRK, E., GÜLCÜ, B., ERCAN, İ., YILMAZLAR, T. (2016). Cinsiyet Fournier gangreni prognozuna etkili bir faktör değildir: Olgu-eşleme çalışması. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 22 - Sayı: 6, 541–544. https://ajindex.com/articles/324021

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