Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2016 / Cilt: 22 - Sayı: 1

Akut apandisit ve renal kolik ayırımında çok değerli laboratuvar markırları vardır

Laboratory markers has many valuable parameters in the discrimination between acute appendicitis and renal colic

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17–22
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In ROC curve analysis, the area under AUCs for WBC, neutrophil, NLR and PLR were 0.896, 0.916, 0.888 and 0.725, respectively (p<=0.05).CONCLUSION: In the discrimination between patients with renal colic and those without any illness, WBC, RDW, MPV, neutrophil and NLR; in the differentiation between the patients with AA and healthy individuals, WBC, RDW, MPV, neutrophil, lymphocyte, NLR and PLR; and more importantly in the discrimination between patients with AA and those with renal colic who presented to emergency services with abdominal pain WBC, neutrophil, lymphocyte, PLR and NLR can be useful parameters

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: Only one diagnostic parameter is not available for acute appendicitis.
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Key Findings & Data:For the establishment of diagnosis, combination of medical history, clinical, laboratory tests, and radiological imaging modalities are used so as to decrease the rates of negative laparotomy and morbidity secondary to delay in diagnosis.
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Conclusion & Impact:In ROC curve analysis, the area under AUCs for WBC, neutrophil, NLR and PLR were 0.896, 0.916, 0.888 and 0.725, respectively (p<=0.05).CONCLUSION: In the discrimination between patients with renal colic and those without any illness, WBC, RDW, MPV, neutrophil and NLR; in the differentiation between the patients with AA and healthy individuals, WBC, RDW, MPV, neutrophil, lymphocyte, NLR and PLR; and more importantly in the discrimination between patients with AA and those with renal colic who presented to emergency services with abdominal pain WBC, neutrophil, lymphocyte, PLR and NLR can be useful parameters
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: Only one diagnostic parameter is not available for acute appendicitis. For the establishment of diagnosis, combination of medical history, clinical, laboratory tests, and radiological imaging modalities are used so as to decrease the rates of negative laparotomy and morbidity secondary to delay in diagnosis. Thepresent study aimed to determine haematological and inflammatory markers which will be used in the discrimination of acute appendicitis (AA) and renal colic which are the most frequent and indistinguishable causes of abdominal pain in patients applying to the emergency service.METHODS: A total of 215 patients who presented with abdominal pain and who were histopathologically diagnosed as AA, and 200 patients who presented with abdominal pain and who were diagnosed as renal colic were included into the study. Control group consisted of 61 patients without any complaints who came to the outpatient clinics of internal medicine only for blood counts. Analyzed blood samples were WBC, RDW, Hb, MCV, MPV, neutrophil, lymphocyte, NLR and PLR. All differences associated with a chance probability of.05 or less were considered statistically significant.RESULTS: A statistically significant intergroup difference was seen between AA and renal colic groups as for age, WBC, Hb, MCV, neutrophil, lymphocyte, NLR and PLR. A statistically significant intergroup difference was seen between AA and control groups regarding age, WBC, Hb, RDW, MPV, neutrophil, lymphocyte, NLR and PLR. A statistically significant intergroup difference was seen between renal colic and control groups as for age, WBC, RDW, MPV, neutrophil and NLR. In ROC curve analysis, the area under AUCs for WBC, neutrophil, NLR and PLR were 0.896, 0.916, 0.888 and 0.725, respectively (p<=0.05).CONCLUSION: In the discrimination between patients with renal colic and those without any illness, WBC, RDW, MPV, neutrophil and NLR; in the differentiation between the patients with AA and healthy individuals, WBC, RDW, MPV, neutrophil, lymphocyte, NLR and PLR; and more importantly in the discrimination between patients with AA and those with renal colic who presented to emergency services with abdominal pain WBC, neutrophil, lymphocyte, PLR and NLR can be useful parameters

Özet

AMAÇ: Akut apandisitte tek başına tanı koydurucu bir parametre yoktur. Tanıda anamnez, klinik, laboratuvar testleri, radyolojik görüntüleme yöntemleri bir arada kullanılarak negatif laparatomi oranını azaltmak ve tanıda gecikme nedeniyle morbidite oranını artırmamak hedeflenmektedir. Ayırıcı tanıları ekarte etmek bu amaca yardımcı olmaktadır. Biz bu çalışmayla karın ağrısının en sık sebepleri olan apandist ve renal koliğin ayırımında kullanılacak inflamatuvar markerları değerlendirerek ayırıcı tanıda bize sağlayabileceği katkıları irdelemeyi amaçladık.GEREÇ VE YÖNTEM: Çalışmamızda karın ağrısı şikayeti ile gelmiş ve incelemeleri sonucu akut apandisit ön tanısı konularak ameliyata alınan ve patolojik tanısı da akut apandisit olan 215 hastanın verileri ile yine aynı şikayetlerle acil servisimize başvurup yapılan incelemeleri sonucunda renal kolik tanısı konan 200 hastanın verileri geriye dönük olarak yeniden değerlendirildi. Kontrol grubu olarak dâhiliye polikliniğine herhangi bir şikayeti olmayıp, sadece kan sayımı yaptırmak için başvuran 61 hastanın verileri gene geriye dönük olarak değerlendirmeye alındı. Olguların acil servise geliş anında alınan WBC, RDW, Hb, MCV, MPV, nötrofil, lenfosit, NLR ve PLR değerleri incelenmiş olup, p<=0.05 istatistiksel olarak anlamlı kabul edildi. Her bir grup kontrol grubuyla ve birbiriyle karşılaştırıldı. Karşılaştırılmalar yapılırken grupların dağılımına bakıldı, dağılımı normal olan gruplara para-metrik, dağılımı normal olmayan gruplarda nonparametrik testler yapıldı.BULGULAR: Akut apandisit (n=215) ve renal kolik (n=200) grubunda; yaş, WBC, Hb, MCV, nötrofil, lenfosit, NLR ve PLR arasında istatistiksel olarak anlamlı değişiklik olduğu, akut apandisit (n=215) ve kontrol grubunda; yaş, WBC, Hb, RDW, MPV, nötrofil, lenfosit NLR ve PLR arasında istatistiksel anlamlı fark olduğu ve yine renal kolik ve kontrol grubunda; yaş, WBC, RDW, MPV, nötrofil ve NLR arasında istatistiksel fark olduğu görüldü. Hastalara ROC curve analizi yapıldığında WBC, nötrofil, NLR ve PLR'nin AUC altında kalan alanları sırasıyla 0.896, 0.916, 0.888 ve 0.725 olarak tespit edildi.TARTIŞMA: WBC, RDW, MPV, nötrofil ve NLR'nin renal kolik ile herhangi bir rahatsızlığı olmayan hastaların ayırımında ve WBC, Hb, RDW, MPV, nötrofil, lenfosit, NLR ve PLR'nin akut apandist hastalarının herhangi bir rahatsızlığı olmayan hastalardan ayırımında, daha da önemlisi WBC, Hb, nötrofil, lenfosit, PLR ve NLR'nin acil servislerde karın ağrısı ile başvuran hastalarda akut apandisit ile renal kolik ayırımında kullanışlı bir parametre olabileceğini düşünmekteyiz

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Cite This Article

ACAR, E., ÖZCAN, Ö., DELİKTAŞ, H., BEYDİLLİ, H., KIRLI, İ., ALATAŞ, Ö. D., ŞAHİN, C., YILDIRIM, B., BELLİ, A. K. (2016). Akut apandisit ve renal kolik ayırımında çok değerli laboratuvar markırları vardır. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 22 - Sayı: 1, 17–22. https://ajindex.com/articles/323730

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