Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2012 / Cilt: 22 - Sayı: 2

Arteriovenöz malformasyonların manajmanında stereotaktik radyocerrahi: Tek menkez deneyimi

Management of arteriovenous malformations by stereotactic radiosurgery: A single center experience

Pages
107–112
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

SRS comprises an effective alternative to surgery for the treatment of particularly small AVMs inaccessible with surgery.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this monoinstitutional study is to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of arteriovenous malformations (AVM).
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Key Findings & Data:Between June 1998 and July 2011, 51 patients with AVM were treated with linear accelerator-based SRS at our department.
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Conclusion & Impact:SRS comprises an effective alternative to surgery for the treatment of particularly small AVMs inaccessible with surgery.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of this monoinstitutional study is to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of arteriovenous malformations (AVM). Between June 1998 and July 2011, 51 patients with AVM were treated with linear accelerator-based SRS at our department. All patients were preevaluated for AVM size, location, neurological status, previous history of hemorrhage and Spetzler-Martin grading. Treated patients then underwent follow-up to evaluate obliteration and clinical status. Median followup time was 32 months (range; 20-93 months). Spetzler-Martin grade I-II and AVM sizes below 3 cm were associated with increased obliteration rate (p=0.01). The annual hemorrhage risk was 1.9%. No patients experienced deterioration of neurological status at follow-up. LINAC-based SRS is a safe and effective treatment modality in the management of cerebral AVMs. SRS comprises an effective alternative to surgery for the treatment of particularly small AVMs inaccessible with surgery.

Özet

Bu tek merkezli çalışmanın amacı stereotaktik radyocerrahinin (SRS) arteryovenöz malformasyon (AVM) manajmanındaki etkinliğinin değerlendirilmesidir. Kliniğimizde Haziran 1998 ile Temmuz 2011 tarihleri arasında arteryovenöz malformasyonlu 51 hasta Linak tabanlı stereotaktik radyocerrahi ile tedavi edilmiştir. Tedavi öncesinde tüm hastalar AVM boyutu, lokalizasyonu, nörolojik durum, önceden kanama öyküsü ve Spetzler-Martin derecelendirilmesi açısından değerlendirilmiştir. Tedavi sonrasında hastalar obliterasyon durumu ve klinik durum değerlendirmesi için takip edilmiştir. Medyan takip süresi 32 ay (sınırlar; 20-93 ay) idi. Spetzler-Martin derece I-II ve AVM boyutunun 3 cm’den küçük olması artmış obliterasyon oranı ile ilişkiliydi (p=0.01). Yıllık kanama oranı %1.9 idi. Takip süresinde hiçbir hastada nörolojik durumda kötüleşme gözlenmedi. LINAC tabanlı stereotaktik radyocerrahi serebral AVM manajmanı nda güvenli ve efektif bir tedavi modalitesidir. Stereotaktik radyocerrahi özellikle cerrahi ile ulaşılamayan küçük AVM’lerin tedavisi için cerrahiye efektif bir alternatif oluşturmaktadır.

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Cite This Article

DINCOGLAN, F., SAĞER, Ö., GAMSIZ, H., DEMİRAL, S., UYSAL, B., SÜRENKÖK, S., ŞİRİN, S., OYSUL, K., BEYZADEOĞLU, M. M. (2012). Arteriovenöz malformasyonların manajmanında stereotaktik radyocerrahi: Tek menkez deneyimi. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 22 - Sayı: 2, 107–112. https://ajindex.com/articles/323311

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