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Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2011 / Cilt: 21 - Sayı: 3

t(12;21)(p13;q22) translokasyonu ve Near Tetraplodi Bulunan Çocukluk Çağı Akut Lenfoblastik Lösemili Bir Olgu Sunumu

Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report

Mutlu KARKUCAK
Tahsin YAKUT
Birol BAYTAN
Tuna GÜLTEN
A. Mera GÜNEŞ
Pages
192–195
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.

📌 3 Key Takeaways

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Objective & Hypothesis:Fluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL).
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Key Findings & Data:Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Ne ar-tetraploidy.
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Conclusion & Impact:Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Fluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL). Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Ne ar-tetraploidy. Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.

Özet

Pre- B Akut Lenfoblastik Lösemi tanısı konulan 11 yaşında erkek olguda, Floresans insitu hibridizasyon analizinde t(12;21)(p13;q22) translokasyonu ve near-tetraploidi beraber olduğu gösterilmiştir. Bazı çalışmalarda t(12;21)(p13;q22) trans lokasyonunun iyi prognostik etki oluşturduğu belirtmelerine rağmen near-tetraploidinin prognostik etkisi hakkında çok az bil gi vardır. Burada Pre-B Akut Lenfoblastik Lösemili olguda t(12;21)(p13;q22) translokasyonu ile birlikte near tetraplodi bulgu larının birlikte etkisi tartışılmaktadır.

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Cite This Article

KARKUCAK, M., YAKUT, T., BAYTAN, B., GÜLTEN, T., GÜNEŞ, A. M. (2011). t(12;21)(p13;q22) translokasyonu ve Near Tetraplodi Bulunan Çocukluk Çağı Akut Lenfoblastik Lösemili Bir Olgu Sunumu. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 21 - Sayı: 3, 192–195. https://ajindex.com/articles/323275

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