Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2011 / Cilt: 21 - Sayı: 2

İran Mashhad’de yenidoğanlarda hematolojik referans değerlerinin belirlenmesi

Determination of hematologic reference values of neonates in Mashhad - Iran

Pages
101–105
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Especially RBCs and hemoglobin were higher and MCV, WBC and absolute neutrophil count were lower.

📌 3 Key Takeaways

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Objective & Hypothesis:The results of laboratory tests have little practical utility unless clinical studies have ascribed various states of health and disease to intervals of values.
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Key Findings & Data:Between September 2007 and March 2008, 447 healthy neonates with more than 2500 g weight were selected and cord blood specimen was taken using EDTA as the anticoagulant.
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Conclusion & Impact:Especially RBCs and hemoglobin were higher and MCV, WBC and absolute neutrophil count were lower.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

The results of laboratory tests have little practical utility unless clinical studies have ascribed various states of health and disease to intervals of values. Several factors affect hematologic values, including race, environment, time of sampling, test method, blood collection site, gestational age and maternal factors. Since these factors vary in various populations, they can cause differences in reference hematologic values. Between September 2007 and March 2008, 447 healthy neonates with more than 2500 g weight were selected and cord blood specimen was taken using EDTA as the anticoagulant. Complete blood count, hemoglobin, hematocrit, and RBC indices were measured by Sysmex cell counter. Differential leukocyte counts were determined in peripheral blood smear. Data were analyzed by SPSS software (version 11.50). A p value < 0.05 was considered to be significant. Mean values and reference ranges of hematologic parameters were as follows: WBC (x103&#956;l)= 11.62 (5.16-18.2), RBC (x106 &#956;l)= 4.45 ( 3.61-5.29), Hb (g/dl)=15.9 (13-18.8), Hct (%)= 48.3 (39.6-56.9), MCV (fl)= 108.7 (97.5-119.8), MCH (pg)= 35.8 (31.7-40), MCHC (g/dl)= 33 (30.1- 35.2), RDW (%)= 17.1 (14.1-20.3). We observed some differences in hematologic values of neotanal cord blood in comparison with other references which are in use in daily clinical practice. Especially RBCs and hemoglobin were higher and MCV, WBC and absolute neutrophil count were lower.

Özet

Farklı klinik durumlarda interval değerlerinin önemi gösterilmeden laboratuar test sonuçlarının pratik kullanımı mümkün değildir. Irk, çevre, örnek alım zamanı, test yöntemi, kanın örneğinin alındığı bölge, hamilelik yaşı ve anneye ait faktörler hematolojik değerleri etkilemektedir. Bu faktörler toplumlar arasında farklılık gösterdiğinden referans hematolojik değerler de farklı olmaktadır. Eylül 2007 ile mart 2008 tarihleri arasında 2500 gram üzerindeki 447 sağlıklı yenidoğanın kord kanı EDTA’lı tüplere alındı. Sysmex cell counter kullanılarak tam kan sayımı, hemoglobin, hematokrit ve eritrosit indeksleri ölçüldü. Periferik yayma yapılarak diferansiyel lökosit sayılarına bakıldı. Veriler SPSS programı (version 11.5) ile analiz edildi. Anlamlılık düzeyi p <0.05 olarak alındı. Hematolojik parametrelerin ortanca ve aralık değerleri şu şekilde idi: WBC (x103μl)= 11.62 (5.16-18.2), RBC (x106 μl)= 4.45 ( 3.61-5.29), Hb (g/dl)=15.9 (13-18.8), Hct (%)= 48.3 (39.6-56.9), MCV (fl)= 108.7 (97.5-119.8), MCH (pg)= 35.8 (31.7-40), MCHC (g/dl)= 33 (30.1- 35.2), RDW (%)= 17.1 (14.1-20.3). Yeni doğan kord kan örneklerindeki hematolojik değerlerin günlük klinik uygulamada kulanılan diğer referans değerlerden farklı olduğunu bulduk. Eritrosit ve hemoglobin daha yüksek iken, MCV, WBC ve absolü notrofil sayılarının daha düşük olduğu saptandı.

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Cite This Article

KERAMATİ, M. R., MOHAMMADZADEH, A., FARHAT, A. S., SADEGHI, R. (2011). İran Mashhad’de yenidoğanlarda hematolojik referans değerlerinin belirlenmesi. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 21 - Sayı: 2, 101–105. https://ajindex.com/articles/323202

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