Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2015 / Cilt: 25 - Sayı: 3

Endometrium ve Overin Eşzamanlı Primer Kanserleri: Tek Merkezin Sonuçları

Coexisting Primary Cancers of Endometrium and Ovary: Experience of Single Institution

Pages
172–177
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Median follow up was 86.5 months and the 10 year overall survival (OS) rates were 86.0% for patients with SEOC.

📌 3 Key Takeaways

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Objective & Hypothesis:Synchronous primary cancers of the endometrium and ovary (SEOC) occur in approximately 10% of all women with ovarian cancer and 5% of all women with endometrial cancer.
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Key Findings & Data:We aimed to demonstrate the clinic-pathological characteristics and prognosis of patients diagnosed as SEOC.
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Conclusion & Impact:Median follow up was 86.5 months and the 10 year overall survival (OS) rates were 86.0% for patients with SEOC.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Synchronous primary cancers of the endometrium and ovary (SEOC) occur in approximately 10% of all women with ovarian cancer and 5% of all women with endometrial cancer. Diagnosis of these tumors as independent primaries or metastases is necessary for appropriate staging and treatment. We aimed to demonstrate the clinic-pathological characteristics and prognosis of patients diagnosed as SEOC. Clinico-pathological data of cases with SEOC were retrieved from the computerized database of Etlik Zubeyde Hanim Women’s Health and Research Hospital. Twenty-six patients with SEOC who underwent comprehensive surgical staging between 1998 and 2014 were included in study. Mean age at diagnosis of women with primary SEOC in our study was 50.9. Median follow up was 86.5 months and the 10 year overall survival (OS) rates were 86.0% for patients with SEOC. Among the variables only omental involvement independently affected OS (p= 0.008). Most of the tumors were well-differentiated, early stage and of endometrioid cell type. In this study we showed that women with SEOC was often young and mostly have an excellent prognosis.

Özet

Endometrium ve overin senkron gelişen primer tümorleri (SEOT); tüm over kanserli kadınların %10’unda, endometrium kanserli olguların ise %5‘inde görülmektedir. Uygun evreleme ve tedavi için olguların bağımsız primer kanser veya metastatik olup olmadıkları ortaya konmalıdır. Çalışmamızda SEOT tanısı alan olguların klinik ve patolojik özellikleri ile prognozlarının ortaya konması amaçlanmıştır. Hastaların bilgileri Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi bilgisayar kayıtlarından çıkarıldı. 1998 ile 2014 yılları arasında cerrahi evrelendirme yapılmış ve SEOT tanısı almış, toplam yirmialtı hasta çalışmaya dahil edildi. Tanı esnasında ortalama yaş 50.9 idi. Medyan takip süresi 86.5 ay ve 10 yıllık sağkalım oranı %86 olarak bulundu. Prognostik değişkenler içinde, yalnız omental tutulumun genel sağkalımı bağımsız olarak etkilediği görüldü (p= 0.008). Tümörlerin büyük çoğunluğu iyi diferansiye, erken evre ve endometrioid tipte idi. Sonuç olarak SEOT tanısı alan kadınların çoğunlukla genç yaşta oldukları ve prognozlarının yalnız başına over kanserlerine göre belirgin olarak daha iyi olduğu ortaya konmuştur.

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Cite This Article

NARIN, M. A., KARALÖK, M. A., BAŞARAN, D., ÜREYEN, I., TÜRKMEN, O., TURAN, A. T., TULUNAY, G. (2015). Endometrium ve Overin Eşzamanlı Primer Kanserleri: Tek Merkezin Sonuçları. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 25 - Sayı: 3, 172–177. https://ajindex.com/articles/323154

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