Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2009 / Cilt: 19 - Sayı: 4

Spinal anestezinin eritrosit sedimentasyon hızına etkisi

The effects of spinal anesthesia on erythrocyte sedimentation rate

Pages
237–241
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

In conclusion, we suggest that spinal anesthesia does not lead to a significant alteration in ESR, which may be accounted for the low amount of local anesthetics used in this technique and the low peak plasma concentrations of those were reached in the blood.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to investigate the effect of spinal anesthesia on erythrocyte sedimantation rate (ESR).
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Key Findings & Data:After approval by the local ethics committee and written informed patient consent, patients between the ages between the ages of 18-65 and American Society of Anesthesiologists (ASA) physical status classification, Class I-II scheduled for ilioinguinal and anorectal surgery under spinal anesthesia were included in the study.
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Conclusion & Impact:In conclusion, we suggest that spinal anesthesia does not lead to a significant alteration in ESR, which may be accounted for the low amount of local anesthetics used in this technique and the low peak plasma concentrations of those were reached in the blood.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anestezi · spinal · Kan sedimentasyonu

Abstract

The aim of this study was to investigate the effect of spinal anesthesia on erythrocyte sedimantation rate (ESR). After approval by the local ethics committee and written informed patient consent, patients between the ages between the ages of 18-65 and American Society of Anesthesiologists (ASA) physical status classification, Class I-II scheduled for ilioinguinal and anorectal surgery under spinal anesthesia were included in the study. Six patients in whom adequate anesthesia level could not be obtained were excluded from the study. Investigation was completed with the remaining 54 patients (12 female, 42 male). Blood samples were obtained just before spinal anesthesia and after the onset time of sensory blockade for surgery. ESR was measured within two hours with automated Sed Rate Greener device parallel to Westergreen method. Mean ESR values were found to be 7.54±6.35 in the first blood samples and 7.37±6.25 in the second blood samples. There was no statistically significant difference between the two ESR values. In conclusion, we suggest that spinal anesthesia does not lead to a significant alteration in ESR, which may be accounted for the low amount of local anesthetics used in this technique and the low peak plasma concentrations of those were reached in the blood.

Özet

Bu çalışmanın amacı spinal anestezinin eritrosit sedimentasyon hızı üzerine etkisini araştırmaktır. Etik kurul izni ve bilgilendirilmiş hasta oluru alındıktan sonra, spinal anestezi ile ilioinguinal ve anorektal cerrahi planlanan 18–65 yaş arası, Amerikan Anestezistler Derneği (ASA) fiziksel durum sınıflaması, Klas I-II hastalar çalışmaya alındı. Cerrahi için yeterli anestezi düzeyi elde edilemeyen 6 hasta çalışma dışı bırakıldı. Geriye kalan 12 kadın, 42 erkek toplam 54 hasta ile araştırma tamamlandı. Hastalardan spinal anestezi için girişim yapılmadan ve cerrahi için duyusal blok başlama zamanından sonra kan örneği alınıp en geç 2 saat içinde eritrosit sedimentasyon hızı, Westergren metoduna paralel otomatize Sed Rate Screener cihazı ile ölçüldü. Ortalama ESR değerleri; 1. kan örnekleri için 7.54 ± 6.35, 2. kan örnekleri için ise 7.37 ± 6.25 mm/saat bulundu. Ancak bu iki değer arasında anlamlı bir fark tespit edilemedi. Sonuç olarak, bu anestezi tekniğinde kullanılan düşük miktardaki ilaç ve bunun kanda ulaşabildiği düşük konsantrasyon nedeniyle spinal anestezinin ESR de önemli bir değişikliğe yol açmadığını düşünüyoruz.

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Cite This Article

HORASANLI, E., BAKIR, F., KILCI, O., ÇİMENCAN, M., ÖZÇİFTÇİ, S., GÖĞÜŞ, N. (2009). Spinal anestezinin eritrosit sedimentasyon hızına etkisi. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 19 - Sayı: 4, 237–241. https://ajindex.com/articles/323080

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