Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2010 / Cilt: 20 - Sayı: 2

Böbrek hücreli karsinomun izole inferior vena cava tutulumuyla görülen geç rekürrensi

Isolated late recurrence of renal cell carcinoma in the inferior vena cava

Pages
115–118
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we report this case and discuss it in the light of current literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Renal cell carcinoma is an urologic malignancy with poor prognosis.
📊
Key Findings & Data:Dissemination to inferior vena cava via renal vein is seen in 4-10% of the patients.
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Conclusion & Impact:Here, we report this case and discuss it in the light of current literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Renal cell carcinoma is an urologic malignancy with poor prognosis. Local invasion and distant metastasis determine the prognosis of the disease. Dissemination to inferior vena cava via renal vein is seen in 4-10% of the patients. The role of radiotherapy and chemotherapy is limited, surgery is the only curative treatment option and patients with liver metastasis also benefit from surgery. In patients with vena cava trombosis, cavotomy and trombectomy should be done to prolong survival, if nodal or visseral metastasis is not present. Surgical procedure differs according to location of trombus in inferior vena cava. In our case report, a patient treated with right nephrectomy due to renal cell carcinoma 3 years ago who was re-operated for vena caval trombus is mentioned. Operation was done without using Pringle technique (clamping of hepatic pedicle) by mobilization of the liver with piggy back technique, and after cavotomy and trombus excision, defect in vena cava was reconstructed with PTFE prosthetic graft. Here, we report this case and discuss it in the light of current literature.

Özet

Böbrek hücreli karsinom (BHK) prognozu kötü olan ürolojik malignitedir. Hastalığın prognozunu tümörün lokal yayılımı ve uzak metastazları belirlemektedir. %4-10 olguda renal ven aracılığıyla inferior vena cavaya (VCI) yayılım görülmektedir. Hastalığın tedavisinde radyoterapi ve kemoterapinin rolü sınırlı olduğundan tek tedavi şekli cerrahidir ve karaciğer metastazlı olgularda cerrahi tedaviden yarar görür. VCI trombüsü olan olgularda eğer nodal yada visseral metastaz yok ise sağ kalım avantajı elde etmek için cavatomi+trombektomi yapılması gerekmektedir. Trombüsün VCI’daki yerleşimine göre cerrahi teknik farklılık göstermektedir ve literatürde farklı teknikler sunulmaktadır. Çalışmamızda 3 yıl önce böbrek hücreli karsinom nedeniyle sağ nefrektomi uygulanan olguda pringle manevrasını (hepatik pedikül klempajı) kullanmaksızın karaciğer mobilizasyonu için piggy back tekniği kullanılarak cavatomi+trombüs eksizyonundan sonra cava’daki defekt PTFE prosthetik greft ile rekonstrükte edilen olgu sunulmuş ve literatür eşliğinde tartışılmıştır.

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Cite This Article

KAZIMİ, M., UĞUZ, A., YAKAN, S., NART, D., ZEYTUNLU, M., GÖKER, E., ÇOKER, A. (2010). Böbrek hücreli karsinomun izole inferior vena cava tutulumuyla görülen geç rekürrensi. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 20 - Sayı: 2, 115–118. https://ajindex.com/articles/323074

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References (17)

  1. Golimbu M, Joshi P, Sperber A, et al. Renal cell carcinoma: survival and prognostic factors. Urology 27: 291-301, 1986
  2. Motzer RJ, Bander NH, Nanus DM. Renal-cell carcinoma. N Engl J Med 335: 865-875, 1996
  3. Hatcher PA, Paulson DF, Anderson EE. Accuracy in staging of renal cell carcinoma involving vena cava. Urology 39: 27-30,1992
  4. Swierzewski DJ, Swierzewski MJ, Libertino JA. Radical nephrectomy in patients with renal cell carcinoma with venous, vena caval, and atrial extension. Am J Surg 168: 205-209, 1994
  5. Berg AA. Malignant hypernephroma of the kidney, its clinical course and diagnosis, with a description of the author’s method of radical operative cure. Surg Gynecol Obstet 17: 463-471, 1913
  6. Nesbitt JC, Soltero ER, Dinney CP. Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus. Ann Thorac Surg 63: 1592-1600, 1997
  7. Hatcher PA, Anderson EE, Paulson DF, et al. Surgical management and prognosis of renal cell carcinoma invading the vena cava. J Urol 145: 20-24, 1991
  8. Guinan P, Sobin LH, Algaba F. TNM staging of renal cell carcinoma: Workgroup no
  9. Union International Contre le Cancer and the American Joint Committee on Cancer. Cancer 80: 992-993, 1997
  10. Karavias D, Tepetes K, Karatzas T, et al. Liver resection for metastatic non-colorectal non-neuroendocrine hepatic neoplasms. Eur J Surg Oncol 28: 135-139, 2002
  11. Detry O, Warzee F, Polus M, et al. Liver Resection for Noncolorectal, Nonneuroendocrine Metastases. Acta chir belg 103: 458-462, 2003
  12. Neves RJ, Zincke H. Surgical treatment of renal cancer with vena cava extension. Br J Urol 59: 390-395, 1987
  13. Staehler M, Rohrmann K, Bachmann A, et al. Therapeutic approaches in metastatic renal cell carcinoma. BJU Int 95: 1153-61, 2005
  14. Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 349: 427-34, 2003
  15. Patel PH, Chaganti RS, Motzer RJ. Targeted therapy for metastatic renal cell carcinoma. Br J Cancer 94: 614-9, 2006
  16. Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 24: 16-24, 2006
  17. Belis JA, Pae WE Jr, Rohner TJ Jr, et al. Cardiovascular evaluation before circulatory arrest for removal of vena caval extension of re