SavedAdd your journal

Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2007 / Cilt: 17 - Sayı: 3

Botriyoid tip embriyonal nazofaringeal rabdomyosarkomanın olağandışı beyin ve temporal kemik metastazı

Unusual brain and temporal bone metastases of a botryoid type of embryonal nasopharyngeal rhabdomyosarcoma

Mustafa KAZKAYASI
Fulya KÖYBAŞOĞLU
Pages
157–162
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We believe that this tumor may spread to distant sites by different ways, and its biological course is typically fatal, particularly if recognized in advanced stages.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We present a 2 year-old boy with a botryoid type of embryonal nasopharyngeal rhabdomyosarcoma with an unusual outcome.
📊
Key Findings & Data:Temporal bone metastasis with brain invasion was detected one year after therapy had been completed.
💡
Conclusion & Impact:We believe that this tumor may spread to distant sites by different ways, and its biological course is typically fatal, particularly if recognized in advanced stages.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Süt çocuğu · Erkek · Neoplazm metastazı

Abstract

We present a 2 year-old boy with a botryoid type of embryonal nasopharyngeal rhabdomyosarcoma with an unusual outcome. Temporal bone metastasis with brain invasion was detected one year after therapy had been completed. Despite multidisciplinary therapeutic approach, distant metastases occurred in the mastoid and squamous portions of the temporal bone with invasion of the temporal lobe. We review the clinical features of head and neck rhabdomyosarcoma and emphasize the importance of distant tumor metastasis. We believe that this tumor may spread to distant sites by different ways, and its biological course is typically fatal, particularly if recognized in advanced stages.

Özet

Olağan dışı klinik seyir gösteren botriyoid tip embriyonal nazofaringeal rabdomyosarkomu bulunan 2 yaşındaki hasta sunulmuştur. Tedavi tamamlandıktan bir yıl sonra beyin invazyonu ve temporal kemik metastazı bulundu. Multi-disipliner terapötik yaklaşıma rağmen, hastada temporal kemiğin skuamöz ve mastoid parçası ve temporal lobda uzak metastaz gelişti. Baş boyun rabdomyosarkomları hakkında literatür gözden geçirildi ve uzak metastazların önemini vurgulandı. Bu tümör farklı yollarla uzak metastaz yayılımını yapabilmekte ve özellikle ileri evrelerde belirlendiğinde biyolojik seyri tipik olarak ölümcül olmaktadır.

🔖

Cite This Article

KAZKAYASI, M., KÖYBAŞOĞLU, F. (2007). Botriyoid tip embriyonal nazofaringeal rabdomyosarkomanın olağandışı beyin ve temporal kemik metastazı. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 17 - Sayı: 3, 157–162. https://ajindex.com/articles/323038

References (14)

  1. Ito F, Watanabe Y, Harada T, Horibe K. Cerebral metastasis of alveolar rhabdomyosarcoma in an infant with multipl skin nodules. J Pediatr Hematol Oncol 19: 466-469, 1997
  2. Pappo AS, Bowman LC, Furman WL, et al. A phase II trial of high-dose methotrexate in previously untreated children and adolescents with high-risk unresectable or metastatic rhabdomyosarcoma. J Pediatr Hematol Oncol 19: 438-442, 1997
  3. Weiss SW, Goldblum JR. Rhabdomyosarcoma. In: Enzinger and Weiss's Soft Tissue Tumors. 4th ed. Missouri, Mosby, 2001: 785-835
  4. Cemiloglu R, Tekalan SA, Patiroglu T, Unlu Y. Rhabdomyosarcoma of the temporal bone: clinical report. Arch Otorhinolaryngol 244: 195-197, 1987
  5. Wells SC. Embryonal rhabdomyosarcoma of the ear: A review of the literature and case history. J Laryngol Otol 98: 1261-1266, 1984
  6. R. Corbett, J. Pritchard, P.N. Plowman. Sarcomas of the head and neck. Tumours of the head and neck, In: Scott-Brown’s Otolaryngology. Kerr AG, Adams DA, Cinnamond MJ (eds). 6th ed. Oxford, Butterworth-Heinemann, Vol.6, Chp.31, 1997: 6-9
  7. Kraus DH, Saenz NC, Gollamudi S, et al. Pediatric rhabdomyosarcoma of the head and neck. Am J Surg 174: 556-560, 1997
  8. Said H, Phang KS, Razi A, et al. Rhabdomyosarcoma of the middle ear and mastoid in children. J Laryngol Otol 102: 614-619, 1988
  9. Newton WA Jr, Gehan EA, Webber BL, et al. Classification of rhabdomyosarcomas and related sarcomas: pathologic aspects and proposal for a new classification- an Intergroup Rhabdomyosarcoma Study. Cancer 76: 1073-1085, 1995
  10. Goto TK, Yoshiura K, Tanaka T, et al. A followup of rhabdomyosarcoma of the infratemporal fossa region in adults based on the magnetic resonance imaging findings. Case reports. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86: 616-625, 1998
  11. Maurer HM, Beltangady M, Gehan EA, et al. The Intergroup Rhabdomyosarcoma Study-1: a final report. Cancer 61: 209-220, 1988
  12. Baker KS, Anderson JR, Link MP, et al. Benefit of intensified therapy for patients with local or regional embryonal rhabdomyosarcoma: results from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol 18: 2427-2434, 2000
  13. DelBalso AM, Weinstein ZR, Deal JL, et al. Nasopharyngeal rhabdomyosarcoma in an adult with intracranial and intraorbital extension. Ear Nose Throat J 65: 420-423, 1986
  14. Shimada H, Newton WA Jr, Soule EH, et al. Pathology of fatal rhabdomyosarcoma. Report from Intergroup Rhabdomyosarcoma Study (IRS-I and IRS-II). Cancer 59: 459-465, 1987. 15