Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2009 / Cilt: 19 - Sayı: 2

The risk factors, premalignant lesions and chemoprevention oral cavity cancers

Oral kavite kanserlerinde risk faktörleri, premalign lezyonlar ve kemoprevensiyon

Pages
117–126
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were many studies about oral cancer prevention with the use of vitamins (retinoids, beta caroten, alpha tokopherol), and COX inhibitors, and its chemopreventive effects.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The frequency of oral squamous cell carcinoma is increasing worldwide.
📊
Key Findings & Data:Nowadays early detection of premalignant lesions and primary and secondary chemoprevention strategies of oral cancers are investigated.
💡
Conclusion & Impact:There were many studies about oral cancer prevention with the use of vitamins (retinoids, beta caroten, alpha tokopherol), and COX inhibitors, and its chemopreventive effects.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Karsinom · yassı hücreli · Risk faktörleri

Abstract

The frequency of oral squamous cell carcinoma is increasing worldwide. The major risk factors are smoking and alcohol. The other etiologic factors are genetic factors, viral pathogens, nutritional habits. Oral premalignant lesions especially oral leukoplakia can transform into malignant lesions. Despite the advances in therapy, prognosis of oral cancers remains poor. Nowadays early detection of premalignant lesions and primary and secondary chemoprevention strategies of oral cancers are investigated. There were many studies about oral cancer prevention with the use of vitamins (retinoids, beta caroten, alpha tokopherol), and COX inhibitors, and its chemopreventive effects.

Özet

Oral Skuamöz hücreli kanser sıklığı toplumda giderek artmaktadır. En önemli risk faktörleri sigara ve alkol kullanımı olup bazı genetik faktörler, viral ajanlar, beslenme alışkanlıkları etyolojide yer almaktadır. Başta oral lökoplaki olmak üzere oral premalign lezyonlar kansere dönüşme riski taşırlar. Erken tanı ve tedavi yöntemlerine rağmen oral kanserlerin prognozu oldukça kötüdür. Premalign lezyonların erken saptanması, primer ve sekonder prevensiyon stratejileri ile oral kanser gelişiminin engellenmesi güncel araştırma konularıdır. Vitaminler (retinoidler, beta karoten, alfa tokaferol) ve COX inhibitörlerinin oral kanser kemoprevensiyonunda kullanımı ile ilgili çalışmalar mevcuttur.

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Cite This Article

ÖZTÜRK, B., COŞKUN, U., YAMAN, E., KAYA, A. O., YILDIZ, R., BENEKLİ, M., BÜYÜKBERBER, S. (2009). The risk factors, premalignant lesions and chemoprevention oral cavity cancers. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 19 - Sayı: 2, 117–126. https://ajindex.com/articles/323005

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