Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2013 / Cilt: 23 - Sayı: 1

Modifiye-ayakta tedavi tekniği ile tüm vücut ışınlaması: Yarı-iletken diyotlarla in-vivo dozimetri

Total body irradiation using a modified standing technique: İn vivo dosimetry with semiconductor diodes

Pages
43–48
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The observed heterogeneity is acceptable, the technique does not require additional shields or bolus material, the dosimetric verification is simple and fast, the set-up of the patient is easily reprodu cible, and the treatment time is within the acceptable limits for a non-dedicated treatment machine.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to establish a fast and simple online dosimetric verification method for total body irradiation (TBI) using semiconductor diodes.
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Key Findings & Data:Twenty one patients were treated with fractionated TBI (12 Gy, 2 Gy BID) using a modified standing techniqu ebetween February 2010 and March 2012.
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Conclusion & Impact:The observed heterogeneity is acceptable, the technique does not require additional shields or bolus material, the dosimetric verification is simple and fast, the set-up of the patient is easily reprodu cible, and the treatment time is within the acceptable limits for a non-dedicated treatment machine.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to establish a fast and simple online dosimetric verification method for total body irradiation (TBI) using semiconductor diodes. Twenty one patients were treated with fractionated TBI (12 Gy, 2 Gy BID) using a modified standing techniqu ebetween February 2010 and March 2012. The prescribed dose was administered to the patient’s mid-plane at the level of the umbilicus. The lungs were shielded to allow only the absorption of an 8 Gy dose. To verify the dose administered during TBI, 12 s emiconductor diodes were attached to the patient’s skin to measure the entrance and exit doses at six anatomical reference points (umbilicus, lungs, neck, forehead, hand, and knee). An adapted version of the arithmetic method which uses a correction factor was used to calculate the mid-plane doses from the entrance and exit dose measurements. The mid-plane doses were then compared with the expected doses. The results of in vivo dosimetry showed that the mid-plane dose calculations conducted using the adap- ted arithmetic method were consistent with the expectations of the treatment plan. The average percentage dose differences and standard deviations were -0.5 ± 5.3 % for the neck, -2.1 ± 3.7 % for the umbilicus, 2.8 ± 5.2 % for the forehead, and -5.9 ± 11 .1% for the lungs. The extremity doses (hand and knee) were not calculated in the treatment planning program; however they were measured for documentary purposes. In vivo dose verification under TBI conditions was efficiently conducted through the use of semiconductor diodes. The measurement results were consistent with treatment plan dose calculations. The modified standing tech- nique provides a practical method for TBI treatments. The observed heterogeneity is acceptable, the technique does not require additional shields or bolus material, the dosimetric verification is simple and fast, the set-up of the patient is easily reprodu cible, and the treatment time is within the acceptable limits for a non-dedicated treatment machine.

Özet

Bu çalışmada amaç tüm vücut ışınlamasında (TVI) hızlı, kolay ve eşzamanlı bir dozimetrik doğrulama yöntemi olan yarı iletken diyotları klinik uygulamaya geçirmektir. fiubat 2010 ve Mart 2012 tarihleri arasında 21 hastaya modifiye-ayakta tedavi tekniği ile fr aksiyone TVI uygulanmıştır (12 Gy, 2 Gy BID). Tanımlanan doz umbilikus hizasında orta-hatta olacak şekilde uygulandı. Akciğerler toplamda sadece 8 Gy doz soğurulacak şekilde korundu. TVI sırasında verilen dozu doğrulamak için 12 yarı iletken diyot cilt yüzeyine, giriş ve çıkış dozlarını ölçecek şekilde, altı farklı anatomik referans noktasına (umbilikus, akciğer, boyun, alın, el ve diz) yerleştirildi. Orta-hatdozları aritmetik metodun düzeltme faktörü içeren bir uyarlaması ile giriş ve çıkış doz ölçümleri kullanılarak hesaplandı. Daha sonra orta-hat dozları beklenen dozlar ile karşılaştırıldı. İn vivo ölçümler sonucu orta-hat dozu hesabında düzeltme faktörlü aritmetik metod kullanımı ile tedavi planları arasında uyum görülmüştür. Ortalama yüzde farkları ve standart sapmaları boyunda %-0.5 ± 5.3, umbilikusta % -2.1 ± 3.7, alında %2.8 ± 5.2 ve akciğerde %-5.9 ± 11,1 olarak bulunmuştur. Ekstremite dozları (el ve diz) tedavi planlamasında hesaplanmamış, fakat kayıt amaçlı ölçülmüşlerdir. TVI koşullarında in vivo doz doğrulaması yarı iletken diyotlar kullanılarak etkin bir biçimde yapılabilmektedir. Tedavi planlam asından gelen hesaplarla ölçüm sonuçları birbirleriyle uyumludur. Modifiye-ayakta TVI pratik bir tedavi tekniğidir. Heterojenite ek koruma veya bolus gerektirmeden kabul edilebilir değerlerde kalmaktadır. Dozimetrik doğrulama ölçümleri kolay ve hızlı bir biçimde yapıl abilmektedir. Tedavi kolayca tekrarlanabilmekte ve tedavi süresi TVI’a adanmamış tedavi cihazları için makul değerlerde kalabilmektedir.

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Cite This Article

CECEN, Y., SINDIR, B., AKSU, M. G., ÖZDEMİR, B. S., KORCUM, A., TUNÇEL, N., YAVUZ, M. N. (2013). Modifiye-ayakta tedavi tekniği ile tüm vücut ışınlaması: Yarı-iletken diyotlarla in-vivo dozimetri. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 23 - Sayı: 1, 43–48. https://ajindex.com/articles/322897

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