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Journals / Selçuk Tıp Dergisi / 2002 / Cilt: 18 - Sayı: 2

Aerobic bacterial microorganism and antibiotic susceptibility in febril neutropenic patients

Ateşli nötropenik hastalarda aerobik bakteriyel infeksiyon etkenleri ve antibiyotik duyarlılıkları

Nebahat DİKİCİ
Onur URAL
Şamil ECİRLİ
Ümran ÇALIŞKAN
Pages
103–108
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As there are differences in infectious agents and infection sites from one to another center each center must define its own infectious agents, infection sites and antibiotic susceptibilies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to evaluate aerobic bacterial infections which were ocurred in febrile neutropenic patients, infectious agents and their antibiotic susceptibilies.
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Key Findings & Data:Eighty-two febrile neutropenic attacks in 67 patients (42 male, 25 female) between age 2-82 years were evaluated in this study.
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Conclusion & Impact:As there are differences in infectious agents and infection sites from one to another center each center must define its own infectious agents, infection sites and antibiotic susceptibilies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Nötropeni · İlaç direnci · bakteriyel

Abstract

The aim of this study was to evaluate aerobic bacterial infections which were ocurred in febrile neutropenic patients, infectious agents and their antibiotic susceptibilies. Eighty-two febrile neutropenic attacks in 67 patients (42 male, 25 female) between age 2-82 years were evaluated in this study. Two hundred and forty-nine samples were evaluated and 45 pathogen agents (21 from urine, 16 from blood, 3 from wound, 2 from throat, 2 from abcess and 1 from palate sputum) were isolated. 33.3% of these pathogens were gram-positive and 66.7% of them were gram-negative microorganisms. Escherichia coli is the most commonly isolated pathogen and than Staphylococcus aureus, Enterobacter cloaca, Klebsiella pneumoniae are isolated. Staphylococcus aureus was the most common organism isolated from blood. As there are differences in infectious agents and infection sites from one to another center each center must define its own infectious agents, infection sites and antibiotic susceptibilies.

Özet

Bu çalışmada ateşli nötropenik olgularda gelişen aerobik bakteriyel infeksiyonlar, infeksiyon etkenleri ve antibiyotik duyarlılıklarının incelenmesi amaçlanmıştır. Çalışmada 2-82 yaşları arasında 42 erkek, 25 kız toplam 67 hastada 82 ateşli nötropenik atak değerlendirildi. Alınan 249 numuneden 21'i idrar, 16'sı kan, 2'si boğaz, 3'ü yara, 2'si apse ve 1'i damaktan olmak üzere toplam 45 patojen izole edilmiştir. Bunların 15 (%33.3)'i gram-pozitif, 30 (%66.7)'u gram-negatif organizmalardır. Kan kültürlerinden izole edilen patojenlerin ise 9 (%56.25)'u gram-pozitif ve 7 (%43.75)'si gram negatiftir. En sık Escherichia coli ve bunu takiben Staphylococcus aureus, Enterobacter cloaca ve Klebsiella pneumoniae izole edildi. Kandan en sık Staphylococcus aureus izole edildi. infeksiyon etkenleri ve infeksiyon yeri yönünden merkezler arasında farklılıklar izlendiğinden, her merkez kendi infeksiyon etkenlerini, infeksiyon bölgesini ve antibiyotik duyarlılıklarını belirlemelidir.

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Cite This Article

DİKİCİ, N., URAL, O., ECİRLİ, Ş., ÇALIŞKAN, Ü. (2002). Aerobic bacterial microorganism and antibiotic susceptibility in febril neutropenic patients. Selçuk Tıp Dergisi, Cilt: 18 - Sayı: 2, 103–108. https://ajindex.com/articles/319372

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References (15)

  1. Cnanock SJ, Pizzo PA. Fever in the neutropenic host. Infect Dis Clin North Am 1996; 10: 777-93
  2. Akova M. Kanser hastalarında bakteriyel infeksiyonlara yaklaşım ve empirik antimikrobiyal tedavi. Flora 1998; 3:3-13
  3. Brown AE. Neutropenia, fever and infection. Am J Med 1984; 76: 421-8
  4. Hughes WT, Armstrong D, Bodey GP, Feld R, Mandell GL, Meyers JD et al. Guidelines for the use of antimi¬ crobial agents in neutropenic patients with unexplained fever. J Infect Dis 1990; 161: 381-96
  5. Glauser MP. Neutropenia: clinical implications and modulation. Intensive Care Med 2000; 26: 103-10
  6. Aygen B. Febril nötropenik hastalarda ampirik antibiy¬ otik tedavisi. İn: Bal Ç, Gür D, Söylebir G, Sünerkan B, Dündar V. editors. Klinik laboratuvar uygulamaları, IV. Antibiyotik Kemoterapi Günleri İstanbul: Dinç ofset; 1999: p. 38-50
  7. De Pauw BE, Donnelly JP. Infections in the immuno- compromised host: general principles. In: Mandell GL, Dolin R, Bennett JE, editors. Principles and Practice of Infectious Diseases. 5th ed. New York: Churchill Livingstone; 2000: p. 3079-89
  8. Vartivarin S, Bodey GP. Infections associated with malignancy. In: Gorbach SL, Bartlett JG, Blacklow, edi¬ tors. Infectious Diseases, First edition. WB Saunders Company; 1992; p. 1035-9
  9. Pizzo PA. Evaluation of fever in the patient with cancer. Eur J Cancer Clin Oncol 1989; 25: 9-16
  10. De Pauw BE, Meunier F. Infections in petients with acute leukemia and lymphoma. In: Mandell GL, Dolin R, Bennett JE, editors. Principles and Practice of Infectious Diseases. 5th ed. New York: Churchill Livingstone, 2000; p. 3090-102
  11. Lucas KG, Brown AE, Armstrong DA, Chapman D, Heller G. The identification of febrile, neutropenic chil¬ dren with neoplastic disease at low risk for bacteremia and complications of sepsis. Cancer 1996; 77: 791-8
  12. Jones GR, Konsler GK, Dunaway RP, Dunaway RP, Pusek SN. Infection risk factors in febrile, neutropenic children and adolescents. Pediatr Hematol Oncol 1996; 13:217-29
  13. Petrilli AS, Melaragno R, Barros KTV. Fever and neu¬ tropenia in children with cancer: a therapeutic approach related to the underlying disease. Pediatr Infect Dis J 1993; 12:916-21
  14. Rubin SJ. Specimen collection and processing. In: Howard BJ, editor. Clinical and Pathogenic Microbiology. First edition, Toronto: Washington D.C, The C.V. Mosby Company, 1987: p. 207-30
  15. Sonnewirth AC. Collection and culture of specimens and guides for bacterial identification. In: Sonnewirth AC, Tare