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Journals / Selçuk Tıp Dergisi / 2002 / Cilt: 18 - Sayı: 2

Effects of bilateral overektomy and unilateral nephrectomy on other renal tissue

Bilateral overektomi ve unilateral nefrektominin diğer böbrek dokusu üzerine olan etkileri

Canpolat Leyla KOYUTÜRK
Neriman ÇOLAKOĞLU
Pages
83–88
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our results showed that gonadal steroids may have a role in modulating acut renal ischaemia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The renin angiotensin system is thought to be modulated by gonadal steroids.
📊
Key Findings & Data:After unilateral nephrectomy and unilateral nephrectomy + bilateral ovariectomy, occured changes were investigated in this study.
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Conclusion & Impact:Our results showed that gonadal steroids may have a role in modulating acut renal ischaemia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Modeller · hayvan · Modeller

Abstract

The renin angiotensin system is thought to be modulated by gonadal steroids. After unilateral nephrectomy and unilateral nephrectomy + bilateral ovariectomy, occured changes were investigated in this study. Right nephrectomized and rigth nephrectomized + bilateral ovariectomized female rats left kidneys were examined histopathologically after four week. Severe inflammatory reaction was observed in only nephrectomized rats after four week. Moreover acut renal ischaemia was observed in the unilateral nephrectomized + total ovariectomized rats left kidney. Our results showed that gonadal steroids may have a role in modulating acut renal ischaemia.

Özet

Renin antiotensin sisteminin gonadal steroidlerle düzenlendiği düşünülmektedir. Bu çalışmada unilateral nefrektomi ve unilatreal nefrektomi + bilateral ovarektomi sonrasında diğer böbrek dokusunda meydana gelen histopatolojik değişiklikler araştırıldı. Dişi sıçanlara sağ nefrektomi ve bilateral overektomi uygulandı. Sol böbrekler ise bir ay sonra histolojik incelemelerde bulunmak üzere alındı. Sadece nefrektomi uygulaması, böbrek dokusunda, şiddetli inflamatuvar reaksiyon geliştirdi. Overektomi + unilateral nefrektomi, akut renal iskemiye neden oldu. Iskemi sonucu böbrek dokusunda hasar gelişti. Sonuçlarımız gonadal steroidlerin, akut renal iskemiyi düzenleyen bir role sahip olduğunu gösterdi.

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Cite This Article

KOYUTÜRK, C. L., ÇOLAKOĞLU, N. (2002). Effects of bilateral overektomy and unilateral nephrectomy on other renal tissue. Selçuk Tıp Dergisi, Cilt: 18 - Sayı: 2, 83–88. https://ajindex.com/articles/319370

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