Journals / Selçuk Tıp Dergisi / 2008 / Cilt: 24 - Sayı: 2

Sensory neuropathy developing consequence of contact N-hexane contained materials for long term

N-heksan bulunduran maddelere uzun süreli temas sonucu gelişen duyusal nöropati

Pages
105–108
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the history of the patient without any known systemic diseases, it was found out that the patient was a cell phone technician for the last 3 years, and that he was particularly exposed to hexan-based chemicals for the purpose of the stabilization of electrical pressure circuits on cell phones in very inappropriate conditions and for a long time.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: N-hexane is a commonly used alyphatic hydrocarbon derivative due to being an expensive solvent, and known as having neurotoxic characteristics.
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Key Findings & Data:Case Report: A 50 year old man applied to the Neurology policlinic with the complaint of numbness first starting on the feet, then radiating to the legs and hands 3 years ago.
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Conclusion & Impact:In the history of the patient without any known systemic diseases, it was found out that the patient was a cell phone technician for the last 3 years, and that he was particularly exposed to hexan-based chemicals for the purpose of the stabilization of electrical pressure circuits on cell phones in very inappropriate conditions and for a long time.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Orta yaşlı · Erkek · Polinöropatiler

Abstract

Aim: N-hexane is a commonly used alyphatic hydrocarbon derivative due to being an expensive solvent, and known as having neurotoxic characteristics. A case being exposed to hexane based chemicals for the purpose of the stabilization of electrical pressure circuits on cell phones and developing sensory neuropathy owing to the exposure was aimed to be discussed in the light of the literature. Case Report: A 50 year old man applied to the Neurology policlinic with the complaint of numbness first starting on the feet, then radiating to the legs and hands 3 years ago. On his neurologic examination, no pathologic findings were found except for the finding in the form of glove-sock hypoesthesy. In the history of the patient without any known systemic diseases, it was found out that the patient was a cell phone technician for the last 3 years, and that he was particularly exposed to hexan-based chemicals for the purpose of the stabilization of electrical pressure circuits on cell phones in very inappropriate conditions and for a long time. On the examination of his EMG, widespread peripheric pure sensory neuropathy was determined. Other causes leading to sensory neuropathy were excluded. It was thought that sensory neuropathy may be dependent on the longterm exposure to hexan-based chemicals for the purpose of the stabilization of electrical pressure circuits on cell phones in inappropriate conditions. Conclusion: Dependent on long- term n-hexane exposure, peripheric sensory neuropathy may develop in those dealing with cell phones becoming widely used in recent years, and the maintenance of these cell phones after their mechanic defects.

Özet

Amaç: N- Heksan, ucuz bir çözücü olması nedeniyle oldukça yaygın olarak kullanılan alifatik bir hidrokarbon türevi olup nörotoksik özellikleri olduğu bilinmektedir. Cep telefonu elektrik baskı devrelerinin stabilizasyonu amaçlı heksan içerikli kimyasal maddelere uzun süreli maruz kalan ve buna bağlı duyusal nöropati gelişen bir olgunun literatür ışığında tartışılması amaçlandı. Olgu Sunumu: 50 yaşında erkek hasta 3 yıl önce ayak tabanından başlayan bacaklarına ve ellerine yayılan uyuşukluk yakınması ile başvurdu. Nörolojik muayenede, eldiven-çorap tarzında hipoestezi dışında patoloji tespit edilmedi. Bilinen sistemik hastalık öyküsü olmayan hastanın özgeçmişinde son 3 yıldır cep telefonu tamirciliği yaptığı ve özellikle cep telefonu elektrik baskı devrelerinin stabilizasyonu amaçlı heksan içerikli kimyasal maddelere uzun süreli ve uygunsuz koşullarda maruz kaldığı öğrenildi. EMG’de yaygın periferik duyusal nöropati saptandı. Duyusal nöropatiye yol açabilecek diğer nedenler dışlandı. Duyusal nöropatinin özgeçmişindeki özellikle cep telefonu elektrik baskı devrelerinin stabilizasyonu amaçlı heksan içerikli kimyasal maddelere uzun süreli ve uygunsuz koşullarda maruz kalmasına bağlı olabileceği düşünüldü. Sonuç: Son yıllarda oldukça geniş ve sık kullanım alanına giren cep telefonu ve bunların mekanik arızaları sonrası bakımları ile uğraşanlarda uzun süreli n-heksan maruziyetine bağlı periferik duyusal nöropati gelişebilir.

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Cite This Article

GÜNEY, F., KOZAN, H. H., İLHAN, N. (2008). Sensory neuropathy developing consequence of contact N-hexane contained materials for long term. Selçuk Tıp Dergisi, Cilt: 24 - Sayı: 2, 105–108. https://ajindex.com/articles/319161

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References (10)

  1. Hormes JT, Filley CM, Rosenberg NL. Neurologic sequelae of chronic solvent vapor abuse. Neurology 1986; 36: 698-702
  2. Paulson GW, Waylonis GW. Polyneuropathy due to n-hexane. Arch Int Med 1976; 136: 880-2
  3. Dittmer DK, Jhamandas JH, Johnson ES. Gluesniffing neuropathies. Can Fam Physician 1993;39: 1965-71
  4. Altenkirch H, Mager J, Stoltenburg G, Helmbrecht J. Toxic polyneuropathies after sniffing a glue thinner. J Neurol 1977; 214: 137-52
  5. Schaumburg H, Spencer PS. Degeneration in central and peripheral nervous system produced by pure n-hexane: An experimental study. Brain 1976; 99: 183-92
  6. Anthony DC, Boekelheide K, Graham DG. The effect of 3,4- dimethyl substitution on the neurotoxicity of 2,5- hexanedionne. Toxicol Appl Pharmacol 1983; 71: 362-71
  7. Ruff RL, Petito CK, Acheson LS. Neuropathy associated with chronic low level exposure to n-hexan. Clin Toxicol 1981; 18: 515-9
  8. Graham DG, Anthony DC, Szakal-Quin G, Gottfried MR, Boekelheide K. Covalent crosslinking of neurofilaments in the pathogenesis of n-hexane neuropathy. Neurotoxicol 1985; 6: 55-64
  9. Selkoe D, Luckenbill-Edds L, Shelanski ML. Effects of neurotoxic ındustrial solvents on cultured neuroblastoma cells: methyl n-butylketone, n-hexan and derivatives. Brain 1978; 105: 768-89
  10. Oh SJ. N-Hexan Neuropathy. In: Clinical Electromyography: Nerve Conduction Studies. 2nd ed. USA: Williams Wilkins; 1993: 604.