Journals / Selçuk Tıp Dergisi / 2008 / Cilt: 24 - Sayı: 3

The effects of intraarticular administration of sufentanil, morphine and plasebo on postoperative pain and analgesic requirements

İntraartikuler sufentanil, morfin ve plasebonun postoperatif ağrı ve analjezik kullanımı üzerine etkileri

Pages
139–143
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a result we concluded that intraarticular sufentanil using in artroscopic knee procedures is simple, effective, safe and well tolerated analgesic techinique.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of this study was to evaluate the effects of intraarticular administration of sufentanil and morphine on postoperative pain and analgesic requirements after artroscopic knee procedures.
📊
Key Findings & Data:A standart general anesthesia was used for all patients At the end the surgery , before the artroscope was removed the following solutions were administerd in 20 ml of normal saline.
💡
Conclusion & Impact:Conclusion: As a result we concluded that intraarticular sufentanil using in artroscopic knee procedures is simple, effective, safe and well tolerated analgesic techinique.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Analjezikler · Ağrı · ameliyat sonrası

Abstract

Aim: The aim of this study was to evaluate the effects of intraarticular administration of sufentanil and morphine on postoperative pain and analgesic requirements after artroscopic knee procedures. Material and Method: Sixty patients scheduled for artroscopic knee surgery were randomised into three groups. A standart general anesthesia was used for all patients At the end the surgery , before the artroscope was removed the following solutions were administerd in 20 ml of normal saline. Group I:(n:20) 20 ml normal saline, Group II:(n:20) 10mg sufentanil, Group III:(n:20) 2 mg morphine. Awaken time of the patients was estimated as time 0 and Visual Analog Scale (VAS) scores were assesed. IV PCA (Patient Controlled Analgesia) was given as tramadol. The PCA deliveries at 30 min, 2 hours, 12 hours and 24 hours and total tramadol requirements for 24 hours were noted. Result: VAS scores were significantly lower in group II(p< 0.05). The consumption of tramadol at 30 min was also lower in group II when compared to group I and group III (p<0.05). Intraarticular sufentanil significantly reduced the postoperative consumption of analgesics (p<0.05). Conclusion: As a result we concluded that intraarticular sufentanil using in artroscopic knee procedures is simple, effective, safe and well tolerated analgesic techinique. This study showed that the onset of analgesia was faster and stronger with intraarticular sufentanil.

Özet

Amaç: Bu çalışmada intraartiküler sufentanil ve morfinin postoperatif ağrı ve analjezik kullanımı üzerine olan etkilerinin araştırılması amaçlandı. Gereç ve Yöntem: Artroskopik diz cerrahisi geçirecek 60 olgu üç gruba ayrıldı. Hastalara standart anestezi uygulandı. Operasyon sonunda artroskop çekilmeden, ilaçlar toplam verilecek mayi 20 cc olacak şekilde serum fizyolojik ile sulandırılarak, Grup I’de 20 cc izotonik (n:20), Grup II’de 10 mg sufentanil (n:20), Grup III’de 2mg morfin (n:20) intraartiküler uygulandı. Hastaların uyandıkları saat 0. dk kabul edilerek VAS’ları değerlendirildi. Tramadol 1 mg/kg yükleme, 20 mg bolus ve 7 dk kilitli kalma süresi olacak şekilde hasta kontrollü analjezi (HKA) ile uygulandı. Bu andan itibaren 30. dk, 2.saat, 12. saat ve 24. saat larda hastaların HKA istekleri ve bir günlük tramadol tüketimleri kaydedildi. Bulgular: Sufentanil grubunda 0. dk VAS değerleri diğer gruplara göre anlamlı derecede düşüktü (p< 0.05). 30. dk kullanılan tramadol miktarı Grup II’de Grup I ve III’e göre anlamlı derecede azdı (p<0.05). ‹ntraartiküler verilen sufentanilin postoperatif tramadol kullanımını azalttıgı gözlendi. Sonuç: Sonuç olarak; intraartiküler sufentanil kullanımı artroskopik diz cerrahisinde kolay uygulanan, efektif, güvenilir ve iyi tolere edilen bir analjezik tekniktir. Bu çalışmada intraartiküler sufentanil ile etki başlangıcının daha kısa ve güçlü olduğu gösterilmiştir.

🔖

Cite This Article

REİSLİ, R., TUNCER, S., YEL, M., SARKILAR, G., EROL, A., ÇİÇEK, F., OTELCİOĞLU, Ş. (2008). The effects of intraarticular administration of sufentanil, morphine and plasebo on postoperative pain and analgesic requirements. Selçuk Tıp Dergisi, Cilt: 24 - Sayı: 3, 139–143. https://ajindex.com/articles/319159

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Heard SO, Edwards WT, Ferrari D, Hanna D, Wong PD, Liland A et al. Analgesic effect of intraarticular bupivacaine or morphine after artroscopic knee surgery: a randomised, prospective, double blind study. Anesth Analg 1992; 74: 822-6
  2. Joshi GP, McCarroll SM, O’Brien TM, Lenane P. Intraarticular analgesia following knee arthroscopy. Anesth Analg 1993; 76: 333-6
  3. Jorish JL, Dubner R, Hargreaves KM. Opioid Analgesia at periferal sites: a target for opioids released during stres and inflammation. Anesth Analg 1987; 66: 1277-81
  4. Stein C. Peripheral mechanisms of opioid analgesia. Anesth Analg 1993;76:182-91
  5. Khoury GF, Chen AC, Garland DE, Stein C. Intrarticular morphine, bupivacaine, and morphine/ bupivacaine for pain control after knee videoarthroscopy. Anesthesiology 1992; 77: 263-6
  6. Vranken JH, Kris CP, Vissers CP, Jongh R, Heylen R. Intraarticular sufentanil administration facilitates recovery after day-case knee arthroscopy. Anesth Analg 2001; 92: 625-8
  7. Lyons B, Lohan D, Flynn CG, Joshi GP, O’Brien TM, McCarroll M. Intra-articular analgesia for arthroscopic menisectomy. Br J Anaesth. 1995;5: 552-5
  8. De Andres J, Valia JC, Barrea l, Colomina R. Intraarticular analgesia after arthroscopic knee surgery: comparison of three different regimens.Eur J Anaesthesiol 1998;15: 10-5
  9. Rosseland LA, Stubhaug A, Skoglund A, Breivik H. Intraarticular morphine for pain relief after knee artroscopy. Arthroscopy 2001;17:477-80
  10. Kazemi AP, Rezazadeh S, Gharacheh HR. Pain relief after arthroscopic knee surgery- intraarticular sufentanil vs morphine. Middle East J Anesthesiol 2004; 17:1099-112
  11. Joshi GP, McCarroll SM, Cooney CM, Blunnie WP, O’Brien TM, Lawerence AJ. Intra-articular morphine for pain relief after knee arthroscopy. J Bone Joint Surgery (Br) 1992; 74: 749-51
  12. Henderson RC, Campion ER, DeMasi RA, Taft TN. Postartroscopy analgesia with bupivacaine: a prospective, randomised, blinded evaluation. Am J Sports Med 1990:18: 614-7
  13. Haddox JD, Weisman SL, Denson DD, Hord AH, Hammonds WD. Analgesic effects of intraarticular morphine after knee surgery. New Eng J Med 1992;329: 895
  14. Niemi L, Pitkanen M, Tuominen M, Bjorkenheim JM, Rosenberg PH. Intraarticular morphine for pain relief after knee artroscopy performed under regional anaesthesia. Acta Anaesth Scan 1994; 38: 402-5
  15. Stein C, Comissel K, Haimerl E, Yassouridisn A,Lehrberger K, Herz A et al. Analgesic effect of intraraticular morphine after artroscopic knee surgery.