Journals / Solunum / 2014 / Cilt: 16 - Sayı: 1

Clinical Utility of Red Blood Cell Distribution Width Parameter in Patients with Hemodynamically Stable Acute Pulmonary Embolism

Journal
Solunum
Pages
27–30
DOI
—
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Red cell distribution width values of the moderate-risk group were significantly higher than those of the low-risk group (14.77±0.54 vs. 14.09±0.43; p=0.036, respectively).Conclusion: Analysis of RDW values can help to determine the low and moderate risk levels of hemodynamically stable patients with acute PE

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Objective & Hypothesis:Objective: Patients with acute pulmonary embolism (PE) presenting with persistent hypotension or shock are considered to be high-risk, while hemodynamically stable patients with acute PE are classified as low- or moderate-risk, depending on their right ventricular dysfunction and/or levels of biomarkers indicating myocardial injury.
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Key Findings & Data:Methods: All patients diagnosed with acute PE in our hospital between 2008 and 2010 were retrospectively included in the study.
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Conclusion & Impact:Red cell distribution width values of the moderate-risk group were significantly higher than those of the low-risk group (14.77±0.54 vs. 14.09±0.43; p=0.036, respectively).Conclusion: Analysis of RDW values can help to determine the low and moderate risk levels of hemodynamically stable patients with acute PE
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Patients with acute pulmonary embolism (PE) presenting with persistent hypotension or shock are considered to be high-risk, while hemodynamically stable patients with acute PE are classified as low- or moderate-risk, depending on their right ventricular dysfunction and/or levels of biomarkers indicating myocardial injury. In this study, we assessed the clinical benefits of knowing the red cell distribution width (RDW) parameter in patients with hemodynamically stable acute PE. Methods: All patients diagnosed with acute PE in our hospital between 2008 and 2010 were retrospectively included in the study. Patients with hypotension, a history of malignancy, heart failure, and/or anemia were excluded. Patients with normotensive acute PE were divided into either a low- or moderate-risk group. This classification was made according to echocardiographic right ventricular dysfunction, positive troponin T, and the level of NT-proBNP. Red cell distribution width values of low and moderate acute PE risk groups were compared.Results: Thirty-two patients were assessed as moderate-risk and 34 patients were low-risk PE. Red cell distribution width values of the moderate-risk group were significantly higher than those of the low-risk group (14.77±0.54 vs. 14.09±0.43; p=0.036, respectively).Conclusion: Analysis of RDW values can help to determine the low and moderate risk levels of hemodynamically stable patients with acute PE

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Cite This Article

PAZARLI, A. C., BEKAR, L. (2014). Clinical Utility of Red Blood Cell Distribution Width Parameter in Patients with Hemodynamically Stable Acute Pulmonary Embolism. Solunum, Cilt: 16 - Sayı: 1, 27–30. https://ajindex.com/articles/314511

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References (13)

  1. Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galiè N, Pruszczyk P, et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the task force for the diagnosis and management of acute pulmonary embolism of the european society of cardiology (ESC). Eur Heart J 2008
  2. [CrossRef] Konstantinides S. Pulmonary embolism: impact of right ventricular dys- function. Curr Opin Cardiol 2005
  3. [CrossRef] Kucher N, Rossi E, De Rosa M, Goldhaber SZ. Massive pulmonary embo- lism. Circulation 2006
  4. [CrossRef] Kreit JW. The impact of right ventricular dysfunction on the prognosis and therapy of normotensive patients with pulmonary embolism. Chest 2004
  5. [CrossRef] Becattini C, Vedovati MC, Agnelli G. Prognostic value of troponins in acute pulmonary embolism: a meta-analysis. Circulation 2007
  6. [CrossRef] Kucher N, Goldhaber SZ. Cardiac biomarkers for risk stratification of pa- tients with acute pulmonary embolism. Circulation 2003
  7. [CrossRef] Puls M, Dellas C, Lankeit M, Olschewski M, Binder L, Geibel A, et al. Heart- type fatty acid-binding protein permits early risk stratification of pulmo- nary embolism. Eur Heart J 2007
  8. [CrossRef] Karnad A, Poskitt TR. The automated complete blood cell count. Use of the red blood cell volume distribution width and mean platelet volume in evaluating anemia and thrombocytopenia. Arch Intern Med 1985
  9. [CrossRef] Felker GM, Allen LA, Pocock SJ, Shaw LK, McMurray JJ, Pfeffer MA, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardi- ol 2007
  10. [CrossRef] Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation 2008
  11. [CrossRef] Fukuta H, Ohte N, Mukai S, Saeki T, Asada K, Wakami K, et al. Elevated plasma levels of B-type natriuretic peptide but not C-reactive protein are associated with higher red cell distribution width in patients with coro- nary artery disease. Int Heart J 2009
  12. [CrossRef] Hampole CV, Mehrotra AK, Thenappan T, Gomberg-Maitland M, Shah SJ. Usefulness of red cell distribution width as a prognostic marker in pul- monary hypertension. Am J Cardiol 2009
  13. [CrossRef] Dabbah S, Hammerman H, Markiewicz W, Aronson D. Relation between red cell dis