Journals / Solunum / 2008 / Cilt: 10 - Sayı: 3

The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients

Astımlı hastalarda obezite ile demografik özellikler, hastalık şiddeti ve atopi arasındaki ilişki

Journal
Solunum
Pages
163–167
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The causative relation between obesity and severity of asthma needs to be clarified with new and more detailed studies.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: In this study we aimed to evaluate the relationship between obesity and gender, age, education status, atopy and severity of disease in asthma patients.
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Key Findings & Data:MATERIALS-METHOD: Asthmatics diagnosed in our chest diseases clinic (261 patients) were enrolled to study, and their BMI (kg/m2) were analyzed.
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Conclusion & Impact:The causative relation between obesity and severity of asthma needs to be clarified with new and more detailed studies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yaş faktörü · Obezite · Hastalık ciddiyet indeksi

Abstract

AIM: In this study we aimed to evaluate the relationship between obesity and gender, age, education status, atopy and severity of disease in asthma patients. MATERIALS-METHOD: Asthmatics diagnosed in our chest diseases clinic (261 patients) were enrolled to study, and their BMI (kg/m2) were analyzed. RESULTS: The mean age of asthmatic patients (195 female, 66 male) was 48.4 ± 16.2. Frequency of obesity in female asthmatics was higher than in male asthmatics (in females 44%, in males 23%; p<0.05). In female asthmatics older than 50 years, and in those education level was primary school or lower, frequency of obesity was higher (p<0.001). There was no relationship between obesity and atopy (p>0.05). Severity of disease was found to be correlated with the increase in the frequency of obesity (p<0.001). Also in all patients there was linear relationship in spearman correlation between BMI and asthma severity (r = 0.326, p<0.001) and age (r = 0.361, p<0.001). A negative correlation between BMI and FVC value (r = -0.325, p<0.001) was detected. In the multivariate logistic regression analysis, risk factors for obesity were found to be as follows: Female asthmatics older than 50 years [odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.2?4.0], education level of primary school or lower (OR = 2.8, 95% CI) = 1.4?5.5, moderate persistent asthma (OR = 5.1, 95% CI = 1.3?19.4), and severe persistent asthma (OR = 5.1, 95% CI = 1.3?21.6). CONCLUSION: In this study, frequency of obesity in female asthmatics was higher in lower educational level and in age older than 50 years. Severity of disease correlated with frequency of obesity. The causative relation between obesity and severity of asthma needs to be clarified with new and more detailed studies.

Özet

AMAÇ: Bu çalışmada astımlı hastalarda obezite ile cinsiyet, yaş, eğitim durumu, atopi ve hastalık şiddeti arasındaki ilişkiyi incelemeyi amaçladık. GEREÇ-YÖNTEM: Göğüs Hastalıkları polikliniğimizde astım tanısı konulan 261 hasta çalışmaya alındı. Hastaların vücut kitle indeksi (VKİ) (kg/m2) hesaplandı. BULGULAR: Bu çalışmadaki astımlıların (195 kadın, 66 erkek) yaş ortalaması 48.4 ± 16.2 idi. Kadın hastalarda erkek hastalara göre obezite sıklığı daha fazla idi (Kadınlarda %44, erkeklerde %23, p= 0.003). Elli yaşın üzerinde ve ilkokul ve daha düşük eğitimli kadın astımlılarda obezite sıklığı daha fazla idi (p 0.05). Hastalık şiddeti arttıkça obezite sıklığının arttığı saptandı (p<0.001). Astımlı hastalarda spearman korelasyon katsayısında VKİ ile astım şiddeti (r = 0.326, p<0.001) ve yaş (r = 0.361, p<0.001) arasında doğrusal ilişki saptandı. VKİ ile FVC değeri arasında ise negatif ilişki (r = -0.325, p<0.001) saptandı. Multivariate lojistik regresyon analizinde obezite için risk faktörleri şu şekilde bulundu. Elli yaşın üzerinde [odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.2?4.0], ilkokul ve daha düşük seviyede eğitimli (OR = 2.8, 95% CI = 1.4?5.5), orta persistan astımlı (OR = 5.1, 95% CI = 1.3?19.4) ve ileri persistan astımlı olmak (OR = 5.1, 95% CI = 1.3?21.6). SONUÇ: Bu çalışmada özellikle düşük eğitimli ve 50 yaş üzerindeki kadın astımlılarda obezite sıklığı daha fazla saptandı. Astım şiddeti arttıkça obezite sıklığı da artmaktaydı. Astım şiddeti ile obezite arasındaki nedensel ilişkinin açıklanabilmesi için daha detaylı çalışmalar yararlı olacaktır.

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Cite This Article

TALAY, F., KURT, B. (2008). The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients. Solunum, Cilt: 10 - Sayı: 3, 163–167. https://ajindex.com/articles/314442

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