Journals / Solunum / 2014 / Cilt: 16 - Sayı: 2

Akut Akciğer Hasarı Deney Modeller Emine Yılmaz Sipahi1

Experimental Models of Acute Lung Injury

Journal
Solunum
Pages
69–77
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After mentioning the reasons and physiopathology of ARDS briefly, the purpose of this review is to summarise the most common experimental animal models and the features of these models.

📌 3 Key Takeaways

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Objective & Hypothesis:Although many various models have been improved in order to form human features of Acute Respiratory Distress Syndrome (ARDS) in animals, there is no single animal model that satisfactorily exhibits all of the histopathological components of human ARDS.
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Key Findings & Data:Therefore, when choosing an ARDS animal model, it is important to consider the ARDS key property to be tested as a study hypothesis and choose the most appropriate model that can display that property.
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Conclusion & Impact:After mentioning the reasons and physiopathology of ARDS briefly, the purpose of this review is to summarise the most common experimental animal models and the features of these models.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although many various models have been improved in order to form human features of Acute Respiratory Distress Syndrome (ARDS) in animals, there is no single animal model that satisfactorily exhibits all of the histopathological components of human ARDS. Therefore, when choosing an ARDS animal model, it is important to consider the ARDS key property to be tested as a study hypothesis and choose the most appropriate model that can display that property. After mentioning the reasons and physiopathology of ARDS briefly, the purpose of this review is to summarise the most common experimental animal models and the features of these models.

Özet

Hayvanlarda insan Akut respiratuar distres sendromu (ARDS) özelliklerini oluşturmaya yönelik olarak çok sayıda farklı modeller geliştirilmiştir, fakat insan ARDS'sindeki histopatolojik bileşenlerin tümünü tatminkar düzeyde sergileyen tek bir hayvan modeli yoktur. Bu yüzden bir ARDS hayvan modelini seçerken, çalışma hipotezi olarak test edilecek olan ARDS anahtar özelliğini dikkate almak ve sonra o özellikleri sergileyebilecek en uygun modeli oluşturmak önemlidir. Bu derlemenin amacı, ARDS'nin nedenlerine ve fizyopatolojisine kısaca değindikten sonra, en çok kullanılan deneysel hayvan modellerini ve bu modellerin özelliklerini özetlemektir.

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Cite This Article

SİPAHİ, E. Y., ATALAY, F. (2014). Akut Akciğer Hasarı Deney Modeller Emine Yılmaz Sipahi1. Solunum, Cilt: 16 - Sayı: 2, 69–77. https://ajindex.com/articles/314314

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