Journals / Solunum / 2015 / Cilt: 17 - Sayı: 2

Farklı Bir OSAS Klinik Tipi: REM İlişkili OSAS

A Different Clinical Type of OSAS: REM-Related OSAS

Journal
Solunum
Pages
92–97
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Similarities between groups in age, body mass index, and concomitant disease suggest that REM-related OSAS is a different clinical type of OSAS, rather than the early phase of OSAS

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Rapid eye movement (REM) is an entity in which the collapsibility of upper respiratory tract increases.
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Key Findings & Data:Patients with an initial diagnosis of sleep-related breathing disorders were later diagnosed to have OSAS based on an apnea-hypopnea index (AHI) of >=5 and were divided into the following two groups: patients with AHINREM of <5 and AHIREM/AHINREM of >2 whose REM recordings were obtained for at least 30 min were defined as having "REM-related OSAS," and those who did not meet this description were defined as having "non-REM-related OSAS." Results: A total of 329 patients with a mean age of 51±10 years were included in the study.
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Conclusion & Impact:Conclusion: Similarities between groups in age, body mass index, and concomitant disease suggest that REM-related OSAS is a different clinical type of OSAS, rather than the early phase of OSAS
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Rapid eye movement (REM) is an entity in which the collapsibility of upper respiratory tract increases. Different opinions have been proposed with regard to the definition of REM-related obstructive sleep apnea syndrome (OSAS). Some authors consider REM-related OSAS as the first presentation, and others consider it as a different clinical type of OSAS. We aimed to compare the clinical and polysomnographic findings of REM-related and non-REM-related OSAS patients to test whether REM-related OSAS is a different clinical type OSAS or the manifestation of early stage or the onset of OSAS. Methods: The study had a retrospective design. Patients with an initial diagnosis of sleep-related breathing disorders were later diagnosed to have OSAS based on an apnea-hypopnea index (AHI) of >=5 and were divided into the following two groups: patients with AHINREM of <5 and AHIREM/AHINREM of >2 whose REM recordings were obtained for at least 30 min were defined as having "REM-related OSAS," and those who did not meet this description were defined as having "non-REM-related OSAS." Results: A total of 329 patients with a mean age of 51±10 years were included in the study. Thirty-five (10.6%) patients with OSAS were REM-related and 294 (89.4%) were non-REM-related. Age, body mass index, smoking status, and concomitant diseases were comparable between groups (p>0.05). In REM-related patients, AHI was lower, REM duration was longer, and mean oxygen saturations were comparatively higher (p<0.05). Conclusion: Similarities between groups in age, body mass index, and concomitant disease suggest that REM-related OSAS is a different clinical type of OSAS, rather than the early phase of OSAS

Özet

Amaç: Uykuda hızlı göz hareketlerinin görüldüğü (Rapid Eye Movement) REM dönemi, faringeal kas aktivitesinin azalarak üst solunum yolu kollapsının belirgin arttığı, obstrüktif solunumsal olayların sıklığı ve süresinin arttığı, oksijen desatürasyonunun daha fazla görüldüğü bir dönemdir. REM ilişkili obstrüktif uyku apne sendromu (obstructive sleep apnea syndrome, OSAS), varlığı ve tanımlanması konusunda farklı görüşlerin ileri sürüldüğü, kimilerince OSAS'ın başlangıç prezentasyonu, kimile- rince farklı bir OSAS klinik tipi olarak sınıflandırılmaktadır. Bu çalışmada REM ilişkili olan ve olmayan OSAS'lı olguların, klinik ve polisomnografi (PSG) özelliklerinin karşılaştırılarak, REM ilişkili OSAS'ın farklı bir OSAS klinik tipi mi, OSAS öncüsü mü olduğu yönünde yargıya varılması amaçlanmıştır. Yöntemler: Çalışma retrospektif olarak yapıldı. Uykuda solunum bozukluğu ön tanısı ile PSG yapılan, apne-hipopne indeksi (AHİ) >= 5 tespit edilerek OSAS tanısı konu- lan olgular iki gruba ayrıldı: AHİNREM 2 olan ve en az 30 dakika süreyle REM kaydı elde edilen olgular ''REM ilişkili OSAS'', bu tanıma uymayanlar ''REM ilişkili olmayan OSAS'' olarak sınıflandırıldı. Bulgular: Yaş ortalaması 51 ± 10 yıl olan 329 olgu çalışmaya alındı. Olguların 35 (%10,6)'i REM ilişkili, 294 (%89,4)'ü REM ilişkili olmayan gruptaydı. Yaş, beden kitle indeksi, sigara öyküsü, ek hastalıklar açısından gruplar benzerdi (p>0,05). REM ilişkili olgularda AHİ daha düşük, REM, NREM Evre 3 süresi daha uzun, ortalama oksijen saturasyonu daha yüksekti (p<0,05). Sonuç: Çalışmamızda grupların yaş, beden kitle indeksi, ek hastalık görülme oranının benzer tespit edilmesi; REM ilişkili OSAS'ın, OSAS'ın erken dönemi veya öncüsü olmaktan çok, farklı bir OSAS klinik tipi olduğunu düşündürmektedir.

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Cite This Article

KÖSEOĞLU, H. İ., KANBAY, A., DEMİR, O. (2015). Farklı Bir OSAS Klinik Tipi: REM İlişkili OSAS. Solunum, Cilt: 17 - Sayı: 2, 92–97. https://ajindex.com/articles/314256

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