Journals / SSK Tepecik Eğitim Hastanesi Dergisi / 1995 / Cilt: 5 - Sayı: 2

Preventive effects of antiosteoporotic treatment in rheumatoid arthritis treated with low-dose steroids

Düşük doz steroid tedavisi uygulanan romatoid artritli olgularda, antiosteporotik sağaltımın koruyucu etkisi

Pages
172–177
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We concluded that low dose steroid treatment could result in osteoporosis and anti-osteoporotic agents such as calcium, vitamin- D, anabolic steroids and calcitonin could be useful in maintaining bone density.

📌 3 Key Takeaways

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Objective & Hypothesis:This study was carried out to see vvhether low dose steroid treatment causes osteoporosis in rheumatoid artritis and to determine the effect of various treatment agents on preventing osteoporosis which is due to the use of low dose steroids.
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Key Findings & Data:This study was performed in 4 groups each of which consisted of 10 rheumatoid arthrit pa-tients.
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Conclusion & Impact:We concluded that low dose steroid treatment could result in osteoporosis and anti-osteoporotic agents such as calcium, vitamin- D, anabolic steroids and calcitonin could be useful in maintaining bone density.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study was carried out to see vvhether low dose steroid treatment causes osteoporosis in rheumatoid artritis and to determine the effect of various treatment agents on preventing osteoporosis which is due to the use of low dose steroids. This study was performed in 4 groups each of which consisted of 10 rheumatoid arthrit pa-tients. Group I: Tt is the control group and only NSAI was used in this group, Group 2- in this group low dose steroid (6mg/ d prednisolone) treatment was given, Group 3: in this group, in addition to low dose steroid treatment calcium, D- vitamin, an¬abolic and calcitonin were given, Group 4: Calcitonin was given in addition to treatment given in group 3. Bone mineral density of ali cases was measured using dual photon absorptiometer before treatment and on the third month of the treatment. We concluded that low dose steroid treatment could result in osteoporosis and anti-osteoporotic agents such as calcium, vitamin- D, anabolic steroids and calcitonin could be useful in maintaining bone density.

Özet

Bu çalışma, romatoid artritte, düşük doz steroid tedavisinin osteoporoz gelişimi üzerindeki etkisini görmek ve değişik tedavi edici ajanların düşük doz steroid kullanılımına bağlı osteopo-rozu önlemede ne kadar etkin olduğunu saptamak amacıyla yapılmıştır.Çalışma, her biri 10 romatoid artritli olguyu içeren 4 grupta yürütülmüştür. 1. Grup: kontrol grubu olup, yalnız non steroid anti inflamatuar, 2. Grup: Düşük doz steroid tedavisi (6mg/ g metilprednisolone) 3. Grup: Düşük doz steroide ek olarak kalsiyum, D- vitamini ve anabolizan, 4. Grup: Grup 3' te ki tedaviye kalsitonin eklendi, Tüm olguların, çalışma öncesi ve 3 aylık tedavi sonrasmda Dual Foton Absorbsiyometresi ile kemik mineral dansitesi ölçüldü. Sonuç olarak, düşük doz steroid tedavisi ile osteoporozun gelişebildiği ve kalsiyum, D- vita¬mini, anabolizan ve kalsitonin gibi antiosteoporotik ajanların, kemik yoğunluğunu korumada yararlı olduğu kanısma varıldı. Ancak bu konuda daha geniş serili ve daha uzun süreli çalışmaların yapılması gerekmektedir.

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Cite This Article

KIYICI, İ., ÖZMEN, B., DOĞANAVŞARGİL, E., KOÇANOĞULLARI, H., OKSEL, F., İNAL, V., GÜMÜŞDİŞ, G. (1995). Preventive effects of antiosteoporotic treatment in rheumatoid arthritis treated with low-dose steroids. SSK Tepecik Eğitim Hastanesi Dergisi, Cilt: 5 - Sayı: 2, 172–177. https://ajindex.com/articles/312839