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Journals / SSK Tepecik Eğitim Hastanesi Dergisi / 2003 / Cilt: 13 - Sayı: 2

A rare type of diabetes mellitus in childhood

Çocukluk çağında ender görülen bir diyabet tipi

Ebru ÖZERKAN
Şule CAN
BAYRAM ÖZHAN
MUHAMMET ALİ KANIK
Ali Rahmi BAKİLER
Pages
105–108
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A moderate decrease in insulin responses to both intravenous glucose tolerance test (IVGTT) and glucagon stimulation test, history of diabetes within the family and no evidence of diabetic complications for ten years without any therapy led us to the possibility of MODY 2 diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Type I diabetes mellitus is the most common form of childhood and adolescent diabetes.
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Key Findings & Data:However, there is an increasing incidence of type 2 diabetes mellitus and subtypes.
💡
Conclusion & Impact:A moderate decrease in insulin responses to both intravenous glucose tolerance test (IVGTT) and glucagon stimulation test, history of diabetes within the family and no evidence of diabetic complications for ten years without any therapy led us to the possibility of MODY 2 diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kadın · İnsülin · Çocuk

Abstract

Type I diabetes mellitus is the most common form of childhood and adolescent diabetes. However, there is an increasing incidence of type 2 diabetes mellitus and subtypes. Maturity Onset Diabetes of Young (MODY) is a relatively prevalent form of these diabetes subgroups. Here, we have reported a patient who had been thought as having MODY 2, with a diabetes started at 2.5 months old. When she had a honeymoon within 4 months of insulin therapy, insulin was stopped and the family had not revisited the hospital again for ten years, because she had no complaint of diabetes. At the second admission at 10 years of age for an inguinal lymphadenomegaly, her blood glucose was measured 407 mg/dl during routine check-up and she was hospitalised again for a research about the type of this diabetes. A moderate decrease in insulin responses to both intravenous glucose tolerance test (IVGTT) and glucagon stimulation test, history of diabetes within the family and no evidence of diabetic complications for ten years without any therapy led us to the possibility of MODY 2 diagnosis.

Özet

Tip l diyabetes mellitus, çocukluk ve adolesan döneminin en sık görülen diyabet tipidir. Ancak, son yıllarda, bu yaş grubunda tip 2 diyabet ve alt grupları da artan sıklıkta tanımlanmaya başlamıştır. Gençlerin Erişkin Tipi Diyabeti (MODY) bunlardan biridir. Bu yazıda, ilk kez 2.5 aylık iken diyabet tanısı almış olan ue MODY 2 tanısı düşünülen bir olgu seyrek görülmesi nedeniyle sunulmuştur. Olgumuz, insulin tedavisi ile 4 ay içinde remisyona girmiş ue sonraki 10 yıl boyunca yakınması olmaması üzerine kontrollere gelmemiş olup, inguinal lenfodenomegali yakınmasıyla başvurduğu sırada ölçülen açlık kan şekerinin 407 mg/dl bulunması nedeniyle hospitalize edilerek diyabet tipi araştırılmıştır. Glukagon uyarısı ve intravenöz glukoz testi sırasında orta derecede yetersiz insulin yanıtı alınması, ailede diyabet öyküsünün varlığı ve diyabetin 10 yıldır komplikasyonsuz seyretmesi nedeni ile olgumuzda MODY 2 tanısı düşünülmüştür.

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Cite This Article

ÖZERKAN, E., CAN, Ş., ÖZHAN, B., KANIK, M. A., BAKİLER, A. R. (2003). A rare type of diabetes mellitus in childhood. SSK Tepecik Eğitim Hastanesi Dergisi, Cilt: 13 - Sayı: 2, 105–108. https://ajindex.com/articles/312832

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