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Journals / SSK Tepecik Eğitim Hastanesi Dergisi / 2004 / Cilt: 14 - Sayı: 1

A rare cause of intracranial hemorrhage in newborn: Hemophilia A

Yenidoğanda intrakraniyal kanamanın nadir bir nedeni: Hemofili A

Nalan KARABIYIK
Zafer SALCIOĞLU
Sibel ÖZBEK
Sultan KAVUNCUOĞLU
Leyla BAYGIN
Pages
57–60
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Besides the hemorrhagic disease of newborn congenital factor deficiencies, although rare, should be kept in mind as a cause of intracranial hemorrhage in term neonates

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Intracranial hemorrhages are rarely seen in term neonates.
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Key Findings & Data:Factor VIII level was detected as 2.5% and the patient was diagnosed as hemophilia A.
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Conclusion & Impact:Besides the hemorrhagic disease of newborn congenital factor deficiencies, although rare, should be kept in mind as a cause of intracranial hemorrhage in term neonates
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Süt çocuğu · yenidoğan · Kafa içi kanamalar

Abstract

Intracranial hemorrhages are rarely seen in term neonates. A term male baby who is delivered spontaneously as the first child of a healthy mother and a father who had a convulsion at his sixth hour of postnatal life is presented. On physical examination, bulging anterior fontanelle was noticed. On cranial ultrasonography intraventricular hemorrhage and ventricular dilatation were detected. Hemorrhage in subarachnoid region and right posteriocerebral tissue were seen on cranial CT. Prothrombin time was normal, whereas activated partial thromboplastin time was prolonged. Factor VIII level was detected as 2.5% and the patient was diagnosed as hemophilia A. After the replacement therapy with concentrated factor VIII the patient was discharged on his 23rd day of hospitalization. Besides the hemorrhagic disease of newborn congenital factor deficiencies, although rare, should be kept in mind as a cause of intracranial hemorrhage in term neonates

Özet

İntrakraniyal kanama, term yenidoğanlarda ender görülen, mortalite ve morbiditenin yüksek olduğu bir klinik durumdur. Bu makalede; zamanında, vajinal yoldan komplikasyonsuz ve ailenin ilk bebeği olarak doğan postnatal 6. saatinde geçirdiği konvülziyon nedeni ile çekilen kraniyal ultrasonografisinde intraventriküler kanama ve ventriküllerde genişleme, tomografide subaraknoid bölgede ve sağ posterior serebral doku içinde kanama tespit edilen erkek olgu protrombin zamanının normal, aktive parsiyel tromboplastin zamanının uzun, faktör VIII düzeyinin %2.5 bulunması nedeni ile hemofili A tanısı alarak sunulmuştur. Faktör VIII replasmanı yapılan olgu yatışının 23. gününde salah ile taburcu edilmiştir. Term yenidoğanlarda, yenidoğanın hemorajik hastalığı yanısıra hemofilinin de ender olarak intrakraniyal kanamaya neden olabileceği, erken tanı ve replasman tedavisinin hayati önem taşıdığı vurgulanmıştır.

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Cite This Article

KARABIYIK, N., SALCIOĞLU, Z., ÖZBEK, S., KAVUNCUOĞLU, S., BAYGIN, L. (2004). A rare cause of intracranial hemorrhage in newborn: Hemophilia A. SSK Tepecik Eğitim Hastanesi Dergisi, Cilt: 14 - Sayı: 1, 57–60. https://ajindex.com/articles/312819

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