Journals / Respiratory Case Reports / 2015 / Cilt: 4 - Sayı: 2

İmmunitesi Sağlam Genç Bir Hastada Beklenmedik Sebebe Bağlı Diffüz Alveoler Hemoraji; Herpes Simplex Tip-1 İlişkili Pnömoni

An Unexpected Cause of Diffuse Alveolar Hemorrhage in an lmmunocompetent Young Patient: Herpes Simplex Type 1 Related Pneumonia

Pages
101–104
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that the current case is a rare disease of HSV-1 lead- ing to DAH

📌 3 Key Takeaways

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Objective & Hypothesis:An 18-year-old man was admitted to the hospital with the complaints of dyspnea, cough and hemopty- sis.
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Key Findings & Data:Laboratory tests revealed a leukocyt count of 21.700/mm3, hemoglobulin level of 6.80 g/dL, hematocrit of 23.2%, CRP of 5.46 mg/dl, and HSV-1 IgM was positive.
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Conclusion & Impact:We think that the current case is a rare disease of HSV-1 lead- ing to DAH
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

An 18-year-old man was admitted to the hospital with the complaints of dyspnea, cough and hemopty- sis. The physical examination revealed, herpes labials on the lower lip and crackles in the middle and lower regions of both lungs. Laboratory tests revealed a leukocyt count of 21.700/mm3, hemoglobulin level of 6.80 g/dL, hematocrit of 23.2%, CRP of 5.46 mg/dl, and HSV-1 IgM was positive. The thorax CT revealed bilateral and diffuse ground glass appear- ance and interlobuler septal thickening on both pul- monary paranchymal areas. Active bleeding was observed in the entire tracheobronchial system by bronchoscopy. Microscopic images showed hemo- siderin-loaded macrophages. We diagnosed HSV-1 related pneumonia and diffuse alveolar hemorrhage (DAH). We treated the patient with acyclovir, cortico- steroid, erythrocyte suspension, cryoprecipitate, and tranexamic acid. The patient improved dramatically. Finally, while HSV-1 related pneumonia is usually seen in immunocompromised hosts and critically ill patients, in the present case, a healthy immunocom- petent man was infected with HSV-1. Following medi- cation, the patient was completely healed. We think that the current case is a rare disease of HSV-1 lead- ing to DAH

Özet

On sekiz yaşında erkek hasta nefes darlığı, öksürük, kanlı balgam şikayetiyle hastanemize başvurdu. Fizik bakıda vital bulguları normaldi. Alt dudakta herpes labialis ve akciğerler orta-alt bölgede inspiratuar raller mevcuttu. Laboratuvarında lökosit 21 .7OO/mm3, hemoglobin 6,80 g/dL, hematokrit %23,2, CRP 5,46mg/dl ve viral panelinde HSV-1 lgM pozitifti. Toraks BT'de her iki akciğerde diffüz buzlu cam opasitesi, interlobuler septal kalınlaşmalar görülmekteydi. Fiberoptik bronkoskopide trakeobron- şial sistemde diffüz eritem ve kanama saptandı. Bronkoalveoler lavajda hemosiderin yüklü makrofajlar görüldü. HSV-l'e bağlı pnömoni ve diffüz alveoler hemoraji (DAH) düşünülen hastaya acyclovir, kortikosteroid, eritrosit süspansiyonu, taze donmuş plazma ve tranexamik asit başlandı. Tedaviye dramatik cevap gelişti. Sonuç olarak, HSV-1 pnömonisinin sıklıkla immün suprese ve yoğun bakım hastalarında görüldüğü bilinmesine karşın olgumuzda immünitesi normal, genç bir hastada HSV-l'e bağlı pnömoni ve DAH kliniğinin geliştiğini görmekteyiz. Bu olgunun HSV-l'e bağlı gelişen, DAH patolojisiyle seyreden ve seyrek görülen bir olgu olduğu kanısındayız.

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Cite This Article

KARATAŞ, M., ÇINARKA, H., KAYHAN, S., GÜMÜŞ, A., BEDİR, R., ÖZYURT, S., ŞAHİN, Ü. (2015). İmmunitesi Sağlam Genç Bir Hastada Beklenmedik Sebebe Bağlı Diffüz Alveoler Hemoraji; Herpes Simplex Tip-1 İlişkili Pnömoni. Respiratory Case Reports, Cilt: 4 - Sayı: 2, 101–104. https://ajindex.com/articles/302528

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