Journals / Mikrobiyoloji Bülteni / 2005 / Cilt: 39 - Sayı: 3

Evaluation of species distribution of yeasts isolated from intensive care units during the four years period

Yoğun bakım ünitelerinden dört yıllık dönemde izole edilen mayaların tür dağılımının değerlendirilmesi

Pages
309–318
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

It was concluded that C.albicans has still been the most frequent species among yeast isolates of ICU's in our hospital; however, the incidence of non-albicans species like C.glabrata and C.tropicalis has increased.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to evaluate the distributions of yeast species according to the years and to detect the emerging pathogens in intensive care units (ICU).
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Key Findings & Data:For this purpose, yeast isolation rates were detected retrospectively, in the following time periods: Period I: April-December 2001; period II: January-December 2002; period III: January-December 2003; period IV: January-December 2004.
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Conclusion & Impact:It was concluded that C.albicans has still been the most frequent species among yeast isolates of ICU's in our hospital; however, the incidence of non-albicans species like C.glabrata and C.tropicalis has increased.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Çapraz enfeksiyon · Görülme sıklığı · Trichosporon

Abstract

The aim of this study was to evaluate the distributions of yeast species according to the years and to detect the emerging pathogens in intensive care units (ICU). For this purpose, yeast isolation rates were detected retrospectively, in the following time periods: Period I: April-December 2001; period II: January-December 2002; period III: January-December 2003; period IV: January-December 2004. A total of 490 yeast isolates recovered from 462 clinical specimens obtained from 360 different ICU patients were investigated during these periods. Urine (62.1%), blood (13.6%) and tracheal aspirate (8.7%) samples were detected as the most common specimens. Of these isolates, 53.3% were identified as Candida albicans, 14.5% as C.tropicalis, 12.2% as C.glabrata, 6.5% as C.parapsilosis, 4.5% as Trichosporon spp., 3.9% as C.kefyr, 1.6% as C.krusei, 1.4% as Geotrichum candidum and 2.1% as other Candida species. The isolation rates of C.albicans in the periods of I to IV were found as 47.7%, 55.5%, 41.7% and 62.4%, respectively. The decrease between the second and third periods, and increase between third and fourth periods were statistically significant (x2=4.15, p=0.04 and x2=8.32, p=0.004). C.glabrata was the second most common species in the first and second periods (14.8% and 15.5%, respectively), followed by C.tropicalis (12.5% and 10.0%, respectively), however this array has changed in the third and fourth periods (C.tropicalis was the second with the rates of 16.7% and 16.8%, while C.glabrata placed in the third line with the rates of 14.8% and 7.6%, respectively). It was concluded that C.albicans has still been the most frequent species among yeast isolates of ICU's in our hospital; however, the incidence of non-albicans species like C.glabrata and C.tropicalis has increased.

Özet

Yoğun bakım ünitelerinde (YBÜ) maya türlerinin dağılımını yıllara göre değerlendirmek ve yeni ortaya çıkan patojenleri saptamak amacıyla gerçekleştirdiğimiz bu çalışmada, dört döneme ayrılan zaman aralıklarında (Dönem I: Nisan-Aralık 2001; dönem II: Ocak-Aralık 2002; dönem III: Ocak-Aralık 2003; dönem IV: Ocak-Aralık 2004) yapılan izolasyonlar retrospektif olarak değerlendirilmiştir. Bu amaçla, 360 farklı YBÜ hastasına ait 462 klinik örnekten izole edilen toplam 490 maya susu incelenmiştir. En sık görülen üç örnek türü idrar (%62.1), kan (%13.6) ve trakeal aspirat (%8.7) olarak belirlenmiştir. Candida izolatlarının tür dağılımları şu şekilde bulunmuştur: C.albicans %53.3, C.tropicafis %14.5, C.glabrata %12.2, C.parapsilosis %6.5, Trichosporon spp. %4.5, C.kefyr %3.9, C.krusei %1.6, Geotrichum candid um %1.4 ve diğer maya türleri %2.1. C.albicans izolasyon oranı I. dönemde %47.7, II. dönemde %55.5, III. dönemde %41.7 ve IV. dönemde %61.4 olarak gözlenmiştir. Bu tür için, dönem II ile III arasındaki azalma ve dönem III ile dönem IV arasındaki artış istatistiksel olarak anlamlı bulunmuştur (x2=4.15, p=0.04 ve x2=8.32, p=0.004). C.tropicalis, dönem I ve H'de sırasıyla %12.5 ve %10.0 oranlarıyla en sık izole edilen üçüncü ve dönem III ile IV'de en sık izole edilen ikinci tür (sırasıyla %16.7 ve %16.8) olmuştur. C.glabrata dönem I ve H'de en sık izole edilen ikinci (sırasıyla %14.8 ve %15.5), C.tropicalis ise (sırasıyla %12.5 ve %10.0) üçüncü tür olurken; dönem III ve IV'de C.tropicalis ikinci sıraya (sırasıyla %16.7 ve %16.8) yükselmiş, C.glabrata ise bu dönemlerde üçüncü sırayş (sırasıyla %14.8 ve %7.6) gerilemiştir. Sonuç olarak, hastanemiz YBÜ maya izolatları arasında C.albicans'm halen en sık izole edilen tür olduğu, ancak C.glabrata ve C.tropicalis gibi albicans dışı türlerin insidanslarında da artış olduğu kanısına varılmıştır.

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Cite This Article

ERGON, M. C., YÜCESOY, M. (2005). Evaluation of species distribution of yeasts isolated from intensive care units during the four years period. Mikrobiyoloji Bülteni, Cilt: 39 - Sayı: 3, 309–318. https://ajindex.com/articles/299650

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References (14)

  1. Fridkin SK, Jarvis WR: Epidemiology of nosocomial fungal infections. Clin Microbiol Rev 1996, 9: 499-511
  2. Beck-Sague CM, Jarvis WR: The National Nosocomial Infections Surveillance System: Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. J Infect Dis 1993, 167: 1247-1251
  3. Pfaller MA, Jones RN, Doern GV, et al: Bloodstream infections due to Candida species: SENTRY antimicrobial surveillance program in North America and Latin America, 1997-1998. Antimicrob Agents Chemother 2000, 44: 747-751
  4. Fridkin SK, Welbel SF, Weinstein RA: Magnitude and prevention of nosocomial infections in the intensive care unit. Infect Dis Clin North Am 1997, 11: 479-496
  5. Hazen KC, Howell SA: Candida, Cryptococcus and other yeasts of medical importance, p. 1693-1711. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH (eds), Manual of Clinical Microbiology. 2003, 8th ed. Amer Soc Microb, Washington DC
  6. Sheehan DJ, Espinel-lngroff A, Moore LS, Webb CD: Antifungal susceptibility testing of yeasts: A brief overview. Clin Infect Dis 1993, 17 (Suppl 2): 494-500
  7. Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC: The Color Atlas and Textbook of Diagnostic Microbiology, p. 983-1069. 1997, 5th ed. Lippincott Company, Philadelphia
  8. Larone DH: Medically Important Fungi: A Guide to Identification, p. 111-143. 2002, 4th ed. Amer Soc Microb, Washington DC
  9. Pfaller MA, Messer SA, Houston A, et al: National epidemiology of mycoses survey: A multicenter study of strain variation and antifungal susceptibility among isolates of Candida species. Diagn Microbiol Infect Dis 1998, 31: 289-296
  10. St-Germain G, Laverdiere M, Pelletier R, et al: Prevalence and antifungal susceptibility of 442 Candida isolates from blood and other normally sterile sites: Results of a 2-year (1996 to 1998) multicenter surveillance study in Quebec, Canada. J Clin Microbiol 2001, 39: 949-953
  11. Güleç S, Karadenizli AY, Bingöl R: Çeşitli klinik örneklerden izole edilen mayaların identifikasyonu
  12. Ulusal Mantar Hastalıkları ve Klinik Mikoloji Kongresi, 4-6 Mayıs 1999, izmir. Tutanaklar, s: 268
  13. Saygan S, Mutlu G, Saygan M ve ark: Çeşitli klinik örneklerden izole edilen Candida türlerinin dağılımı ve antifungal duyarlılıkları. Candida Mikrobiyolojisi ve infeksiyonları Simpozyumu, 21-22 Haziran 2002, Eskişehir. Tutanaklar, s: 194
  14. Çayırlı A, Süzük S, Balaban N, Coşkun S, Bodur H: Klinik örneklerden izole edilen Candida türl