Journals / Mikrobiyoloji Bülteni / 2008 / Cilt: 42 - Sayı: 4

Mediterranean spotted fever due to contact with dog-tick

Köpek kenesi ile temas sonrasında gelişen Akdeniz benekli ateşi

Pages
701–706
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Indirect immunofluorescence assay (IFA) for Rickettsia yielded negative result in the serum sample collected on admission day, however, it was found positive at 1/512 titer in the serum sample collected 10 days after admission.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Mediterranean spotted fever (MSF) is one of the tick-borne rickettsial infections caused by Rickettsia conorii.
📊
Key Findings & Data:In this case report, a 16-years-old male patient who was diagnosed as MSF after an exposure to dog-tick in Bartin province (located at middle Black Sea region of Turkey) has been presented.
💡
Conclusion & Impact:Indirect immunofluorescence assay (IFA) for Rickettsia yielded negative result in the serum sample collected on admission day, however, it was found positive at 1/512 titer in the serum sample collected 10 days after admission.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Rickettsia conorii · Ergen · Arachnid Vektörler

Abstract

Mediterranean spotted fever (MSF) is one of the tick-borne rickettsial infections caused by Rickettsia conorii. It is transmitted to humans by brown dog ticks (Rhipicephalus sanguineus). In this case report, a 16-years-old male patient who was diagnosed as MSF after an exposure to dog-tick in Bartin province (located at middle Black Sea region of Turkey) has been presented. His history revealed that, five days before admission to the hospital (on June, 2007) he had cleaned dog-ticks from his dog, and after 12 hours he found a stucked tick on his leg and he took it out right away with a tweezer. High fever, headache and generalized maculopapular rash including soles and palms and a black-colored lesion at the tick bite site developed three days later. In clinical examination, there was a black escar circled with a red-purple colored halo in front of the right tibia at the site of the tick bite showing high similarity to "tache noire" which was specific to MSF. Indirect immunofluorescence assay (IFA) for Rickettsia yielded negative result in the serum sample collected on admission day, however, it was found positive at 1/512 titer in the serum sample collected 10 days after admission. The patient has recovered completely without any complication after 10 days of doxycycline therapy. The aim of this presentation is to point out that MSF should be considered for the differential diagnosis of a patient with a history of tick bite, fever, maculopapular rash, headache, myalgia, arthralgia and especially with black escar during summer months in our country where the incidence of tick-borne infections has been increasing since recent years.

Özet

Akdeniz benekli ateşi (ABA), Rickettsia conorii'nin etken olduğu kene ile bulaşan riketsiya enfeksiyonlarından biridir. Etken insanlara genellikle enfekte kahverengi köpek keneleri (Rhipicephalus sanguineus) aracılığıyla bulaşır. Bu yazıda Bartın ilinde köpek kenesi ile temas sonrasında ABA gelişen 16 yaşında bir erkek hasta sunulmaktadır. 2007 yılı Haziran ayında hastanemize başvuran olgunun öyküsünden, beş gün önce köpeğinin kenelerini temizlediği, bundan yaklaşık 12 saat sonra bacağına bir kenenin yapıştığını fark ettiği ve keneyi bacağından cımbızla uzaklaştırdığı öğrenilmiştir. Yaklaşık üç gün sonra, olguda yüksek ateş, baş ağrısı, el ve ayak tabanları da dahil olmak üzere tüm vücutta yaygın döküntü ve bacakta kenenin ısırdığı bölgede siyah renkli bir lezyon ortaya çıkmıştır. Fizik incelemede sağ bacak ön yüzünde kenenin ısırdığı alanda saptanan ortası siyah ve çevresinde mor bir halka bulunan lezyon, ABA'ya özgül olan "tache noire" ile uyumlu bulunmuştur. Olgunun ilk başvurusunda ve başvurudan 10 gün sonra alınan serum örneklerinde çalışılan Rickettsia indirekt immünofloresan antikor (İFA) testi ilk serumda negatif, ikinci serumda ise 1/512 dilüsyonda pozitif olarak saptanmıştır. Olgu, 10 günlük doksisiklin tedavisi ile herhangi bir komplikasyon olmaksızın iyileşmiştir. Bu olgu ile, özellikle son yıllarda kene ile ilişkili enfeksiyon insidansının artış gösterdiği ülkemizde, yaz mevsiminde yüksek ateş, makülopapüler döküntü, baş ağrısı, miyalji, artralji şikayetleri ve kene ısırığı öyküsü olan, özellikle ısırık bölgesinde siyah renkli es-kar gelişen olguların ayırıcı tanısında ABA'nın düşünülmesi gerektiğinin vurgulanması amaçlanmıştır.

🔖

Cite This Article

ÖZTOPRAK, N., ÇELEBİ, G., AYDEMİR, H., PİŞKİN, N., BEKTAŞ, S., KOCA, R., KULOĞLU, H. F. (2008). Mediterranean spotted fever due to contact with dog-tick. Mikrobiyoloji Bülteni, Cilt: 42 - Sayı: 4, 701–706. https://ajindex.com/articles/299630

References (1)

  1. Jensenius M, Fournier PE, Raoult D. Tick-borne rickettsioses in international travelers. Int J Infect Dis 2004; 8: 1 39-46. 2.Cascio A, Jaria C. Epidemiology and clinical features of Mediterranean spotted fever in Italy. Parassitologia 2006;48:131-3. 3.Mert A, Ozaras R, Tabak F, Bilir M, Ozturk R. Mediterranean spotted fever: a review of fifteen cases. J Dermatol 2006; 33: 103-7. 4.Kuloglu F, Rolain JM, Fournier PE, Akata F, Tuğrul M, Raoult D. First isolation of Rickettsia conorii from humans in the Trakya (European) region of Turkey. Eur J Clin Microbiol Infect Dis 2004; 23: 609-14. 5.Raoult D, Tissot-Dupont H, Caraco P, Brouqui P, Drancourt M, Charrel C. Mediterranean spotted fever in Marseille: descriptive epidemiology and the influence of climatic factors. Eur J Epidemiol 1992; 8: 192-7. 6.Colomba C, Saporito L, Polara VF, Rubino R, Titone L. Mediterranean spotted fever: clinical and laboratory characteristics of 415 Sicilian children. BMC Infect Dis 2006; 6: 60. 7.Mumcuoglu KY, Frish K, Sarov B, et al. Ecological studies on the brown dog tick Rhipicephalus sanguineus (Acari: Ixodidae) in southern Israel and its relationship to spotted fever group rickettsiae. J Med Entomol 1993; 30": 114-21. 8.Raoult D, Dupont HT, Chicheportiche C, et al. Mediterranean spotted fever in Marseille, France: correlation between prevalence of hospitalized patients, seroepidemiology, and prevalence of infected ticks in three different areas. Am J Trop Med Hyg 1993; 48: 249-56. 9.Azad AF, Beard CB. Rickettsial pathogens and their arthropod vectors. Emerg Infect Dis 1998; 4: 179-86. 10.Brouqui P, Bacellar F, Baranton G, et al. Guidelines for the diagnosis of tick-borne bacterial diseases in Europe. Clin Microbiol Infect 2004; 10: 1108-32. 11.Chipp E, Digby S. Rickettsia: an unusual cause of sepsis in the emergency department. Emerg Med J 2006; 23: e60.