Journals / Mikrobiyoloji Bülteni / 2005 / Cilt: 39 - Sayı: 4

Prospective evaluation of blood cultures in Medical Faculty Hospital of Blacksea Technical University

Karadeniz Teknik Üniversitesi Tıp Fakültesi Hastanesinde kan kültürlerinin prospektif olarak değerlendirilmesi

Pages
455–464
DOI
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Methicillin resistance of S.aureus isolates was determined as 54% in hospital acquired blood stream infections and 25% in community acquired blood stream infections.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, the rate of blood culture contamination, bacterial pathogens and their antimicrobial susceptibilities causing nosocomial and community acquired bloodstream infections were investigated prospectively during the period February 2003 to February 2004.
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Key Findings & Data:In the study period, among the 5994 blood culture samples obtained from 3114 patients, 1091 (18%) yielded positive results.
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Conclusion & Impact:Methicillin resistance of S.aureus isolates was determined as 54% in hospital acquired blood stream infections and 25% in community acquired blood stream infections.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Bakteriler · Streptococcal enfeksiyonlar · Staphylococcus aureus

Abstract

In this study, the rate of blood culture contamination, bacterial pathogens and their antimicrobial susceptibilities causing nosocomial and community acquired bloodstream infections were investigated prospectively during the period February 2003 to February 2004. In the study period, among the 5994 blood culture samples obtained from 3114 patients, 1091 (18%) yielded positive results. Seventy-four of them (1.2%) were evaluated as false positive, 514 (9%) were pseudobacteremia or contamination. According to patients' clinical features, 503 (8%) blood culture samples were associated with blood stream infections, and 358 of them (71%) were primary episodes. Twohundred and ninetyfour of primary episodes (82%) were hospital acquired and 64 were community acquired bloodstream infections. Staphylococcus aureus was the most frequently isolated agent in the hospital and community acquired bloodstream infections at the rates of 16% and 20%, respectively. In hospital acquired blood stream infections, Escherichia coli (9%) and Pseudomonas aeruginosa (8%); in community acquired bloodstream infections Streptococcus spp (17%) and E.coli (15%) were the other most frequently isolated bacterial agents. Methicillin resistance of S.aureus isolates was determined as 54% in hospital acquired blood stream infections and 25% in community acquired blood stream infections.

Özet

Bu çalışmada, Şubat 2003-Şubat 2004 tarihleri arasında hastanemiz kan kültürlerindeki kontaminasyon oranı, hastane ve toplum kaynaklı kan dolaşımı enfeksiyonlarında (KDİ) etken patojenler ve antimikrobiyal duyarlılıklarının prospektif olarak araştırılması hedeflenmiştir. Çalışma periyodunda, 3114 hastaya ait 5994 kan kültürü örneği değerlendirilmiş olup, 1091 (%18) kan kültürü örneğinde üreme saptanmıştır. Bunların 74'ü (%1.2) yalancı pozitif, 514'ü (%9) psödobakteremi ya da kontaminasyon olarak kabul edilmiştir. Hastaların klinik özelliklerine göre, KDİ ile uyumlu bulunan 503 (%8) kan kültürü örneğinin 358'i (%71) primer epizod olup, bunların 294'ü (%82) hastane kaynaklı, 64'ü (%18) ise toplum kaynaklı olarak değerlendirilmiştir. Hastane ve toplum kaynaklı KDİ'lerde sırası ile %16 ve %20 oranında en sık etken olarak Staphylococcus aureus saptanmıştır. Hastane kaynaklı KDİ'lerde Escherichia coli %9, Pseudomonas aeruginosa %8, toplum kaynaklı KDİ'lerde ise Streptococcus spp %17, E.coli %15 en sık izole edilen diğer bakteriyel ajanlardır. S.aureus izolatlarında metisilin direnci hastane kaynaklı KDİ'lerde %54 iken toplum kaynaklı KDİ'lerde %25 olarak saptanmıştır.

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Cite This Article

SUCU, N., ÇAYLAN, R., AYDIN, K., YILMAZ, G., BOZ, A. G., KÖKSAL, İ. (2005). Prospective evaluation of blood cultures in Medical Faculty Hospital of Blacksea Technical University. Mikrobiyoloji Bülteni, Cilt: 39 - Sayı: 4, 455–464. https://ajindex.com/articles/299398

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