Journals / Mikrobiyoloji Bülteni / 2005 / Cilt: 39 - Sayı: 1

A case with fever of unknow origin during treatment for malaria: Multi-drug resistant Salmonella typhi infection

Sıtma tedavisi alan bir olguda nedeni bilinmeyen ateş: Çok ilaca dirençli Salmonella typhı enfeksiyonu

Pages
83–87
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient was treated successfully witrj ciprofloxacin for 14 days.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Typhoid fever is an acute infectious disease caused by Salmonella serotype Typhi, leading to endemic or epidemic outbreaks in tropical/ subtropical countries (especially in India, Southeast Asia, Central and South Africa).
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Key Findings & Data:In this report, a 27 years old male patient with malaria has been presented.
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Conclusion & Impact:The patient was treated successfully witrj ciprofloxacin for 14 days.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İlaç direnci · Nedeni bilinmeyen ateş · Salmonella enfeksiyonları

Abstract

Typhoid fever is an acute infectious disease caused by Salmonella serotype Typhi, leading to endemic or epidemic outbreaks in tropical/ subtropical countries (especially in India, Southeast Asia, Central and South Africa). In this report, a 27 years old male patient with malaria has been presented. The patient was diagnosed to have malaria while working in Afghanistan, and received malaria treatment since one month. He admitted to our hospital because of still continuing high fever, and other complaints (weight loss, night sweats, weakness, anorexia). His fever was 39.5°C at admission, and blood smears were negative for Plasmodium sp. On the third day of admission, rosespots were detected on the skin of the abdomen and chest, and group agglutination tests gave positive results for S. Typhi O (titer: 1/800), and S. Typhi H (titer: 1/3200). Blood cultures revealed growth of Salmonella enterica serotip Typhi. The isolate was found to be resistant to ampicillin, chloramphenicol, tetracyclin and trimethoprim-sulfamethoxazole, and sensitive to ciprofloxacin. The patient was treated successfully witrj ciprofloxacin for 14 days.

Özet

Tifo, Salmonella serotip Typhi'nin neden olduğu akut enfeksiyöz bir hastalık olup, tropikal/subtropikal bölgelerde (özellikle Hindistan, Güneydoğu Asya, Orta ve Güney Afrika) endemi ve epidemilere yol açmaktadır. Bu yazıda, Afganistan'da görev yaptığı sırada sıtma tanısı konularak son bir aydır tedavi alan ancak ateşinin düşmemesi ve şikayetlerinin (kilo kaybı, gece terlemesi, halsizlik, iştansızlık) devam etmesi nedeniyle ülkeye dönerek hastanemize başvuran 27 yaşında bir erkek hasta sunulmaktadır. Başvuru sırasında hastanın ateşi 39.5°C olarak saptanmış ve kan yaymalarında Plasmodium sp. görülmemiştir. Başvurunun üçüncü gününde karın ve göğüste taş rozeler belirlenmiş, yapılan grup aglütinasyonunda S. Typhi O 1/800, S. Typhi H 1/3200 titrelerde pozitif bulunmuştur. Ateşli dönemde alınan kan kültürlerinde üreyen izolatlar, Salmonella enterica serotip Typhi olarak tanımlanmıştır. Disk difüzyon yöntemiyle izolatın ampisilin, kloramfenikol, tetrasiklin ve trimetoprim-sulfametoksazole dirençli, siprofloksasine duyarlı olduğu gözlenmiş ve olgu 14 günlük siprofloksasin tedavisi ile düzelmiştir.

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Cite This Article

AKIN, K., YAVUZDEMİR, Ş., CESUR, S., LEVENT, B., ESEN, B., WILLKE, A. (2005). A case with fever of unknow origin during treatment for malaria: Multi-drug resistant Salmonella typhi infection. Mikrobiyoloji Bülteni, Cilt: 39 - Sayı: 1, 83–87. https://ajindex.com/articles/299011

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