Journals / Mikrobiyoloji Bülteni / 2010 / Cilt: 44 - Sayı: 1

Post-operative bacteremia caused by multidrug-resistant Aerococcus viridans in a patient with gali bladder cancer

Safra kesesi kanseri olan bir hastada operasyon sonrası gelişen çok ilaca dirençli Aerococcus viridans bakteriyemisi

Pages
123–126
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, A.viridans should be suspected as an opportunistic pathogen in immuno-compromised patients and these patients should be treated according to the antibiotic susceptibility test results.

📌 3 Key Takeaways

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Objective & Hypothesis:Aerococcus viridans is a gram-positive, catalase and oxidase negative, microaerophylic and non-mo-tile coccus which is rarely associated with human infections such as endocarditis, meningitis, artritis and bacteremia.
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Key Findings & Data:We report a case of bacteremia due to A.viridans in a 61-years-old man with malignant qa|| bladder neoplasm.
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Conclusion & Impact:In conclusion, A.viridans should be suspected as an opportunistic pathogen in immuno-compromised patients and these patients should be treated according to the antibiotic susceptibility test results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aerococcus viridans is a gram-positive, catalase and oxidase negative, microaerophylic and non-mo-tile coccus which is rarely associated with human infections such as endocarditis, meningitis, artritis and bacteremia. We report a case of bacteremia due to A.viridans in a 61-years-old man with malignant qa|| bladder neoplasm. The patient underwent a surgical operation and on the 5th day of operation he had severe abdominal pain, vomiting, high fever and discharge from operation site. He was transferred to intensive care unit and blood cultures were obtained. Piperacillin-tazobactam was initiated as empirical therapy. Blood cultures performed in Bactec system (Becton Dickinson, USA) yielded catalase negative gram-positive cocci in tetrads. The isolate was pyrrolidonyl aminopeptidase (PYR) positive and produced alfa-hemolysis on sheep blood agar. These cocci were identified as A.viridons by Vitek 2 Compact System (BioMerieux, France) and identification was confirmed by using mini API System (BioMerieux, France) Antibiotic susceptibility testing performed with Kirby-Bauer disk diffusion method revealed that the isolate was susceptible to trimethoprim-sulfamethoxazole, tigecycline and vancomycin and resistant to penicillin, ampicillin, piperacillin-tazobactam, ceftriaxone, erythromycin, clindamycin and amikacin. The patient was successfully treated with vancomycin (2 x 1 g/day) and completely recovered without complication. In conclusion, A.viridans should be suspected as an opportunistic pathogen in immuno-compromised patients and these patients should be treated according to the antibiotic susceptibility test results.

Özet

Aerococcus viridans, gram-pozitif, katalaz ve oksidaz negatif, mikroaerofilik, hareketsiz bir koktur. Klinikte nadiren endokardit, menenjit, artrit ve bakteriyemi gibi farklı enfeksiyonlara neden olmaktadır. Bu raporda safra yolu malign neoplazmı nedeniyle öpere edilen 61 yaşında erkek hastada, A.viridans'm neden olduğu nadir bir bakteriyemi olgusu sunulmaktadır. Cerrahi operasyon geçiren ve 5. günde şiddetli karın ağrısı, kusma, yüksek ateş ve operasyon yerinden akıntısı olan hasta yoğun bakım ünitesine yatırılmıştır. Hastadan kan kültürleri alındıktan sonra ampirik olarak piperasilin-tazobaktam tedavisi başlanmıştır. Kan kültüründe (Bactec, Becton Dickinson, ABD) üreyen gram-pozitif kok morfolojisindeki katalaz negatif bakteri Vitek 2 Compact Sistem (BioMerieux, Fransa) ile A.viridans olarak tanımlanmıştır, izolatın Gram ile boyanmasında, tetrat yapan koklar görülmüş, koyun kanlı ağarda alfa-hemolitik koloniler saptanmış ve PYR (pyrrolidonyl aminopeptidase; Oxoid Ltd, İngiltere) testi pozitif bulunmuştur. A.viridans tanısı ayrıca mini API (BioMerieux, Fransa) sistemi ile de doğrulanmıştır. Kirby-Bauer disk difüzyon metodu ile yapılan antibiyotik duyarlılık testinde, izolatın trimetoprim-sülfametoksazol, tigesiklin ve vankomisine duyarlı; penisilin, ampisilin, piperasilin-tazobaktam, seftriakson, eritromisin, klindamisin ve amikasine dirençli olduğu tespit edilmiştir. Olgu, vankomisin (2 x 1 g/gün) ile başarıyla tedavi edilmiş ve komplikas-yonsuz olarak iyileşmiştir. Sonuç olarak, A.viridans'in özellikle immünyetmezliği olan hastalarda nadiren de olsa fırsatçı enfeksiyon etkeni olabileceği akılda tutulmalı ve antibiyotik duyarlılık testlerine göre tedavi uygulanmalıdır.

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Cite This Article

KORUK, S. T., BAYRAKTAR, M., ÖZGÖNÜL, A., TÜMER, S. (2010). Post-operative bacteremia caused by multidrug-resistant Aerococcus viridans in a patient with gali bladder cancer. Mikrobiyoloji Bülteni, Cilt: 44 - Sayı: 1, 123–126. https://ajindex.com/articles/298869

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